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Philip C. Biggin

south parks road

51H指数
391论文数
8.9K被引数
收录论文 149
发表时间
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Steric control of signaling bias in the immunometabolic receptor GPR84GPR84免疫代谢受体信号偏倚的立体控制
errNature Communications
IF15.7
err2026-09-05
err0
errOAAI
errPinqi Wang; Xuan Zhang; Abdul-Akim Guseinov; Laura Jenkins; Carl von Hallerstein; Jonathan D. Colburn; Rowan Ives; Vincent B. Luscombe; Sara Marsango; Listiana Oktavia; Arun Raja; David R. Greaves; Philip C. Biggin; Graeme Milligan; Cheng Zhang; Irina G. Tikhonova; Angela J. Russell
err分享
err收藏
Author Correction: Structural basis for prostaglandin and drug transport via SLCO2A1作者更正：前列腺素和药物通过SLCO2A1转运的结构基础
errNature Communications
IF15.7
err2026-08-17
err0
errOAAI
errChitra Joshi; Justin C. Deme; Yoshinobu Nakamura; Wei-Tse Hsu; Jonathan D. Goult; Takafumi Kato; Joanne L. Parker; Philip C. Biggin; Susan M. Lea; Takeo Nakanishi; Simon Newstead
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err收藏
Umbrella Sampling Workflows for Fast-Converging PMF Calculations without Artificial WHAM Constraints无人工WHAM约束的快速收敛PMF计算的伞形采样工作流程
errJournal of Chemical Theory and Computation
IF5.5
err2026-05-05
err0
errOAAI
errBjarne Feddersen; Philip C. Biggin
err分享
err收藏
Structural basis for pH-responsive amino acid transport via SLC7A4.SLC7A4介导的pH响应性氨基酸转运的结构基础。
errNature Communications
IF15.7
err2026-03-28
err0
errOAAI
errDimitrios Kolokouris; Anuja Bothra; Takafumi Kato; Yi C. Zeng; Simon Lichtinger; Joanne L. Parker; Philip C. Biggin; Simon Newstead
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err收藏
Structural basis for prostaglandin and drug transport via SLCO2A1SLCO2A1介导前列腺素和药物转运的结构基础
errNature Communications
IF15.7
err2026-03-20
err0
errOAAI
errChitra Joshi; Justin C. Deme; Yoshinobu Nakamura; Wei-Tse Hsu; Jonathan D. Goult; Takafumi Kato; Joanne L. Parker; Philip C. Biggin; Susan M. Lea; Takeo Nakanishi; Simon Newstead
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Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist异构甘氨酸受体域耦合的结构基础由一种非典型别构激动剂揭示
errScience Advances
IF12.5
err2026-02-13
err0
errOAAI
errEric Gibbs; Bjarne Feddersen; Kayla J. Kindig; David Seiferth; Philip C. Biggin; Sudha Chakrapani
err分享
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Developments and challenges in hit progression within fragment-based drug discovery基于片段的药物发现中hit进展的发展与挑战
errNature Communications
IF15.7
err2026-01-31
err0
errOAAI
errHarold Grosjean; Philip C. Biggin
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Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines一种对生物胺具有选择性敏感的异常烟碱乙酰胆碱受体亚型的表征
errCommunications Biology
IF5.1
err2025-12-12
err0
errOAAI
errEleanor L. Mitchell; Emily B. Armstrong; Franco Viscarra; Isabel Bermudez; Philip C. Biggin; James A. Goodchild; Andrew K. Jones
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Can AI-Predicted Complexes Teach Machine Learning to Compute Drug Binding Affinity?AI预测的复合物可以教机器学习来计算药物结合亲和力吗？
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-12-01
err0
PREAI
errHsu, Wei-Tse; Grevtsev, Savva; Herz, Anna M.; Douglas, Thomas; Magarkar, Aniket; Biggin, Philip C.
err分享
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Editorial overview - New Concepts in Drug Discovery (2025)编辑概述 - 新概念药物发现 (2025)
errCurrent Opinion in Structural Biology
IF7
err2025-06-26
err0
PREAI
errPhilip C. Biggin; Roderick E. Hubbard
err分享
err收藏
Narrowing the gap between machine learning scoring functions and free energy perturbation using augmented data使用增强数据缩小机器学习评分函数和自由能扰动之间的差距
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2025-02-08
err0
errOAAI
errValsson, Isak; Warren, Matthew T.; Deane, Charlotte M.; Magarkar, Aniket; Morris, Garrett M.; Biggin, Philip C.
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Discovering chemical structure: general discussion
errFARADAY DISCUSSIONS
IF3.1
err2025-01-01
err0
PREAI
errAspuru-Guzik, Alan; Bechtel, Tim; Bernales, Varinia; Biggin, Philip C.; Bigi, Filippo; Borges Jr, Itamar; Briling, Ksenia R.; Cheung, Joshua; Collins, Christopher M.; Darmawan, Kevion K.; David, Nicholas; Day, Graeme M.; Deringer, Volker L.; Draxl, Claudia; Dyer, Matthew; Eardley-Brunt, Annabel; Evans, Rob; Fairlamb, Ian; Franklin, Barnabas A.; George, Janine; Goulding, Mark; Grundy, Joanna; Hafizi, Roohollah; Hakkennes, Matthijs; Hickey, Niamh; James, Gillian; Juraskova, Veronika; Kalikadien, Adarsh V.; Kapil, Venkat; Kulik, Heather J.; Kumar, Vishank; Kuttner, Christian; Lederbauer, Magdalena; Lou, Yuchen; Mante, Eltjo; Marsh, Liam; Martin, Jennie; Middleton, Clelia; Nematiaram, Tahereh; Pare, Charles W. P.; Pasca, Bianca; Pickard, Chris J.; Ruscic, Branko; Ryder, Matthew R.; Savoie, Brett M.; Sun, Wenhao; Szczypinski, Filip T.; Taniguchi, Takuya; Torrisi, Steven; Vishnoi, Shubham; Walsh, Aron; Wang, Shirui
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Are we fitting data or noise? Analysing the predictive power of commonly used datasets in drug-, materials-, and molecular-discovery
errFARADAY DISCUSSIONS
IF3.1
err2025-01-01
err1
errOAAI
errCrusius, Daniel; Cipcigan, Flaviu; Biggin, Philip C.
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Mechanisms underlying modulation of human GlyRα3 receptors by Zn2+ and pHZn2和pH调节人GlyRα3受体的潜在机制
errSCIENCE ADVANCES
IF12.5
err2024-12-20
err0
PREAI
errKindig, Kayla; Gibbs, Eric; Seiferth, David; Biggin, Philip C.; Chakrapani, Sudha
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Analysis of Glycan Recognition by Concanavalin A Using Absolute Binding Free Energy Calculations
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-10-16
err0
errOAAI
errMusleh, Sondos; Alibay, Irfan; Biggin, Philip C.; Bryce, Richard A.
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Structural basis for antibiotic transport and inhibition in PepT2PepT2中抗生素转运和抑制的结构基础
errNATURE COMMUNICATIONS
IF15.7
err2024-10-09
err0
errOAAI
errParker, Joanne L.; Deme, Justin C.; Lichtinger, Simon M.; Kuteyi, Gabriel; Biggin, Philip C.; Lea, Susan M.; Newstead, Simon
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Exploring the influence of pore shape on conductance and permeation
errBIOPHYSICAL JOURNAL
IF3.1
err2024-09-01
err0
errOAAI
errSeiferth, David; Biggin, Philip C.
err分享
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The mechanism of mammalian proton-coupled peptide transporters哺乳动物质子偶联肽转运体的作用机制
errELIFE
IF0
err2024-07-23
err2
errOAAI
errLichtinger, Simon M.; Parker, Joanne L.; Newstead, Simon; Biggin, Philip C.
err分享
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Automated Absolute Binding Free Energy Calculation Workflow for Drug Discovery
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-07-02
err6
PREAI
errRies, Benjamin; Alibay, Irfan; Anand, Nithishwer Mouroug; Biggin, Philip C.; Magarkar, Aniket
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Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment原核配体门控离子通道glc的cryo-em结构为脂质环境中的门控提供了见识
errNATURE COMMUNICATIONS
IF15.7
err2024-04-05
err2
errOAAI
errBharambe, Nikhil; Li, Zhuowen; Seiferth, David; Balakrishna, Asha Manikkoth; Biggin, Philip C.; Basak, Sandip
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研究方向

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合作期刊
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R
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H 指数: 122 · 论文数: 699
A
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H 指数: 114 · 论文数: 935
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