José M. Lluch - Publications, H-index & Citations

José M. Lluch

Autonomous University of Barcelona

43H指数

332论文数

6.9K被引数

收录论文 96

发表时间

Omega-3 DHA as a blank canvas: A molecular approximation to how lipid mediators modulate LGR6 in inflammation resolution Omega-3 DHA作为空白画布：脂质介质如何调节LGR6以促进炎症消退的分子近似研究

Protein Science

IF5.2

2026-05-20

OAAI

Álex Pérez-Sánchez; Mireia Garcia-Viloca; Àngels González-Lafont; José M. Lluch

Photoswitchable COX-2-Selective Inhibitors as Light-Regulated Anti-Inflammatory Agents 光开关COX-2选择性抑制剂作为光调控抗炎剂

Journal of the American Chemical Society

IF15.6

2026-04-01

OAAI

Morales, Amanda; Cruz, Alejandro; Perez-Sanchez, Alex; D'Avino, Danilo; Galassi, Gaia; Milano, Erica Ginevra; Bernareggi, Irene; Arenos-Bach, Carla; Grazioso, Giovanni; Alibes, Ramon; Hernando, Jordi; Gorostiza, Pau; Rossi, Antonietta; Pistocchi, Anna; Matera, Carlo; Busque, Felix; Gonzalez-Lafont, Angels; Lluch, Jose M.

Exploring allosteric properties of mammalian ALOX15: octyl (N-(4-(benzofuran-2-yl)-2-methoxyphenyl)sulfamoyl)- and octyl (N-(4-(1H-indol-2-yl)-2-methoxyphenyl)sulfamoyl)carbamates as ALOX inhibitors 探索哺乳动物ALOX15的别构特性：辛基(N-(4-(2-苯并呋喃基)-2-甲氧基苯基)磺酰胺基)-和辛基(N-(4-(1H-吲哚-2-基)-2-甲氧基苯基)磺酰胺基)氨基甲酸酯作为ALOX抑制剂

RSC Adv.

IF4.6

2025-09-22

OAAI

Viktor Gavrilyuk; Alejandro Cruz; Vladislav Aksenov; Danila Nurgaliev; Alexander Zhuravlev; Alexey Golovanov; José M. Lluch; Hartmut Kuhn; Igor Ivanov; Àngels González-Lafont

Effect of Leaving Centrosymmetric Character on Spectral Properties in Mono-, Bi-, and Triphotonic Absorption Spectroscopies

ACS OMEGA

IF4.3

2024-09-25

OAAI

Gelabert, Ricard; Moreno, Miquel; Lluch, Jose M.

Theoretical Study of the Arachidonic Acid Conversion into Leukotriene A4 Catalyzed by Human 5-Lipoxygenase: Hydroperoxidation and Epoxidation Mechanisms and Arachidonic Acid Active Site Access

ACS CATALYSIS

IF13.1

2023-12-29

OAAI

Cruz, Alejandro; Gonzalez-Lafont, Angels; Lluch, Jose M.

Three-Photon Infrared Stimulation of Endogenous Neuroreceptors in Vivo

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2023-11-20

OAAI

Sortino, Rosalba; Cunquero, Marina; Castro-Olvera, Gustavo; Gelabert, Ricard; Moreno, Miquel; Riefolo, Fabio; Matera, Carlo; Fernandez-Castillo, Noelia; Agnetta, Luca; Decker, Michael; Lluch, Jose M.; Hernando, Jordi; Loza-Alvarez, Pablo; Gorostiza, Pau

Different Structures-Similar Effect: Do Substituted 5-(4-Methoxyphenyl)-1H-indoles and 5-(4-Methoxyphenyl)-1H-imidazoles Represent a Common Pharmacophore for Substrate Selective Inhibition of Linoleate Oxygenase Activity of ALOX15?

MOLECULES

IF4.6

2023-07-14

OAAI

Zhuravlev, Alexander; Cruz, Alejandro; Aksenov, Vladislav; Golovanov, Alexey; Lluch, Jose M.; Kuhn, Hartmut; Gonzalez-Lafont, Angels; Ivanov, Igor

Molecular Insights into the Regulation of 3-Phosphoinositide-Dependent Protein Kinase 1: Modeling the Interaction between the Kinase and the Pleckstrin Homology Domains

ACS OMEGA

IF4.3

2022-07-15

OAAI

Garcia-Viloca, Mireia; Bayascas, Jose Ramon; Lluch, Jose M.; Gonzalez-Lafont, Angels

N-Substituted 5-(1H-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs: Mechanism of Action

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-01-25

OAAI

Golovanov, Alexey; Zhuravlev, Alexander; Cruz, Alejandro; Aksenov, Vladislav; Shafiullina, Rania; Kakularam, Kumar R.; Lluch, Jose M.; Kuhn, Hartmut; Gonzalez-Lafont, Angels; Ivanov, Igor

A role of Gln596 in fine-tuning mammalian ALOX15 specificity, protein stability and allosteric properties

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

IF3.3

2020-07-01

PREAI

Cruz, Alejandro; Di Venere, Almerinda; Mei, Giampiero; Zhuravlev, Alexander; Golovanov, Alexey; Stehling, Sabine; Heydeck, Dagmar; Lluch, Jose M.; Gonzalez-Lafont, Angels; Kuhn, Hartmut; Ivanov, Igor

Understanding the Molecular Details of the Mechanism That Governs the Oxidation of Arachidonic Acid Catalyzed by Aspirin-Acetylated Cyclooxygenase-2

ACS CATALYSIS

IF13.1

2019-11-18

PREAI

Cebrian-Prats, Anna; Gonzalez-Lafont, Angels; Lluch, Jose M.

Mutations of Triad Determinants Changes the Substrate Alignment at the Catalytic Center of Human ALOX5

ACS CHEMICAL BIOLOGY

IF3.8

2019-10-30

PREAI

Iyanov, Igor; Golovanov, Alexey B.; Ferretti, Cristian; Canyelles-Nino, Miguel; Heydeck, Dagmar; Stehling, Sabine; Lluch, Jose M.; Gonzalez-Lafont, Angels; Kuehn, Hartmut

Discovery of processive catalysis by an exo-hydrolase with a pocket-shaped active site

NATURE COMMUNICATIONS

IF15.7

2019-05-20

OAAI

Streltsov, Victor A.; Luang, Sukanya; Peisley, Alys; Varghese, Joseph N.; Cairns, James R. Ketudat; Fort, Sebastien; Hijnen, Marcel; Tvaroska, Igor; Arda, Ana; Jimenez-Barbero, Jesus; Alfonso-Prieto, Mercedes; Rovira, Carme; Mendoza, Fernanda; Tiessler-Sala, Laura; Sanchez-Aparicio, Jose-Emilio; Rodriguez-Guerra, Jaime; Lluch, Jose M.; Marechal, Jean-Didier; Masgrau, Laura; Hrmova, Maria

Synthetic Photoswitchable Neurotransmitters Based on Bridged Azobenzenes

ORGANIC LETTERS

IF5

2019-05-09

OAAI

Cabre, Gisela; Garrido-Charles, Aida; Gonzalez-Lafont, Angels; Moormann, Widukind; Langbehn, Daniel; Egea, David; Lluch, Jose M.; Herges, Rainer; Alibes, Ramon; Busque, Felix; Gorostiza, Pau; Hernando, Jordi

Comparing Hydrolysis and Transglycosylation Reactions Catalyzed by Thermus thermophilus β-Glycosidase. A Combined MD and QM/MM Study

FRONTIERS IN CHEMISTRY

IF4.2

2019-04-10

OAAI

Romero-Tellez, Sonia; Lluch, Jose M.; Gonzalez-Lafont, Angels; Masgrau, Laura

Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation 合理设计的偶氮苯光开关用于有效的双光子神经元激发

NATURE COMMUNICATIONS

IF15.7

2019-02-22

OAAI

Cabre, Gisela; Garrido-Charles, Aida; Moreno, Miguel; Bosch, Miguel; Porta-de-la-Riva, Montserrat; Krieg, Michael; Gascon-Moya, Marta; Camarero, Nuria; Gelabert, Ricard; Lluch, Jose M.; Busque, Felix; Hernando, Jordi; Gorostiza, Pau; Alibes, Ramon

Unraveling the Molecular Details of the Complete Mechanism That Governs the Synthesis of Prostaglandin G2 Catalyzed by Cyclooxygenase-2

ACS OMEGA

IF4.3

2019-01-25

OAAI

Cebrian-Prats, Anna; Gonzalez-Lafont, Angels; Lluch, Jose M.

Mutagenesis of Sequence Determinants of Truncated Porcine ALOX15 Induces Changes in the Reaction Specificity by Altering the Catalytic Mechanism of Initial Hydrogen Abstraction

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2017-12-14

PREAI

Saura, Patricia; Kaganer, Ilya; Heydeck, Dagmar; Lluch, Jose M.; Kuehn, Hartmut; Gonzalez-Lafont, Angels

Understanding the Molecular Mechanism of the Ala-versus-Gly Concept Controlling the Product Specificity in Reactions Catalyzed by Lipoxygenases: A Combined Molecular Dynamics and QM/MM Study of Coral 8R-Lipoxygenase

ACS CATALYSIS

IF13.1

2017-06-23

OAAI

Saura, Patricia; Suardiaz, Reynier; Masgrau, Laura; Gonzalez-Lafont, Angels; Rosta, Edina; Lluch, Jose M.

Evolutionary alteration of ALOX15 specificity optimizes the biosynthesis of antiinflammatory and proresolving lipoxins (vol 113, pg E4266, 2016)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-11-21

OAAI

Adel, Susan; Karst, Felix; Gonzalez-Lafont, Angels; Pekarova, Maria; Saura, Patricia; Masgrau, Laura; Lluch, Jose M.; Stehling, Sabine; Horn, Thomas; Kuhn, Hartmut; Heydeck, Dagmar

研究方向