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J

Jane X. Kelly

university of georgia
H指数:27
被引数:3,823

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Potent acridone antimalarial against all three life stages of Plasmodium

针对疟原虫的所有三个生命阶段的有效acridone抗疟药

Nature Communications
IF15.7
2026-04-140
OAAI
Papireddy Kancharla; Rozalia A. Dodean; Yuexin Li; Xiaowei Zhang; Sean Kelly; Jordan Charlton; Angely J. Binauhan; Kimberly Navarrete; Laurize Garcia; Jianbing Mu; Jinghua Lu; Diana Caridha; Michael S. Madejczyk; Xiannu Jin; William E. Dennis; Karl Kudyba; Sharon McEnearney; Patricia J. Lee; Cameron Blount; Jesse DeLuca; Chau Vuong; Kristina Pannone; Hieu T. Dinh; Kennedy Mdaki; Susan Leed; Monica L. Martin; Brandon S. Pybus; Geoffrey C. Chin; Anongruk Chim-Ong; Liwang Cui; Tarrick Qahash; Douglas A. Shoue; Michael T. Ferdig; Frank P. Mockenhaupt; Welmoed van Loon; Jules M. Ndoli; Heather Kudyba; Joel Vega-Rodriguez; Martin Okitwi; Oriana Kreutzfeld; Cristina Docan; Carol Green; Ying Liu; Aaron Agulay; Jon Mirsalis; Sarah N. Farrell; Alexandra S. Probst; Aaron Nilsen; P. Holland Alday; J. Stone Doggett; Geoffrey I. McFadden; Christopher D. Goodman; Flaminia Catteruccia; Philip J. Rosenthal; Michael K. Riscoe; Roland A. Cooper; Alison Roth; Jane X. Kelly
Identification of an Orally Efficacious Imidazo[4,5-c]pyridine-6-Carboxamide Antimalarial with a High Barrier to Resistance

一种具有高耐药性屏障的口服有效咪唑[4,5-c]吡啶-6-甲酰胺类抗疟药鉴定

Journal of Medicinal Chemistry
IF6.8
2026-04-010
PRE
Zhou, Bo; Do Amaral, Leticia S.; Bremers, Emily K.; Haney, Reagan S.; Wardlaw, Lyric A.; Merino, Emilio F.; Li, Yuexin; Buchanan, Mairi; Baud, Delphine; Brand, Stephen; Lee, Marcus C. S.; Kelly, Jane X.; Totrov, Maxim; Cassera, Maria B.; Carlier, Paul R.
Optimization of Prodiginines as Single-Dose Curative Antimalarials

单剂量根治性抗疟药Prodiginines的优化

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-11-010
PRE
Kumar, Amrendra; Li, Yuexin; Zhang, Xiaowei; Gaddam, Mahesh; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Chetree, Ravi; Blount, Cameron; DeLuca, Jesse; Vuong, Chau; Kudyba, Karl; Roncal, Norma; Ashraf, Kutub; Lee, Patricia J.; Pannone, Kristina; Leed, Susan; Dinh, Hieu T.; Mdaki, Kennedy; Navarrete, Kimberly; Charlton, Jordan; Binauhan, Angely J.; Qahash, Tarrick; Kibe, Kevin Mugambi; Shoue, Douglas A.; Checkley, Lisa; Ferdig, Michael T.; Chim-Ong, Anongruk; Cui, Liwang; Orena, Stephen; Byaruhanga, Oswald; Assimwe, Jackson; Tibagambirwa, Innocent; Chithanna, Sivanna; Dodean, Rozalia A.; Legac, Jennifer; Kreutzfeld, Oriana; Rosenthal, Philip J.; Cooper, Roland A.; Reynolds, Kevin A.; Roth, Alison; Kelly, Jane X.; Kancharla, Papireddy
Acridone Prodrugs with Enhanced Dual-Stage Antimalarial Efficacy

双阶段抗疟活性增强的喹诺酮前药

ACS Medicinal Chemistry Letters
IF4
2025-06-060
PRE
Rozalia A. Dodean; Yuexin Li; Xiaowei Zhang; Amrendra Kumar; Sovitj Pou; Rolf W. Winter; Katherine M. Liebman; Lev N. Zakharov; Diana Caridha; Michael S. Madejczyk; Chau Vuong; Jesse DeLuca; Geoffrey Chin; Karl Kudyba; Sharon McEnearney; Xiannu Jin; William E. Dennis; Ravi Chetree; Cameron Blount; Kristina Pannone; Hieu T. Dinh; Kennedy Mdaki; Susan Leed; Patricia J. Lee; Alison Roth; Papireddy Kancharla; Jane X. Kelly
Development of Next-Generation Antimalarial Acridones with Radical Cure Potential

下一代具有自由基治愈潜力的抗疟喹诺酮类化合物的发展

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-04-030
PRE
Dodean, Rozalia A.; Li, Yuexin; Zhang, Xiaowei; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Chetree, Ravi; Kudyba, Karl; Mcenearney, Sharon; Lee, Patricia J.; Blount, Cameron; Deluca, Jesse; Vuong, Chau; Pannone, Kristina; Dinh, Hieu T.; Mdaki, Kennedy; Leed, Susan; Martin, Monica L.; Pybus, Brandon S.; Pou, Sovitj; Winter, Rolf W.; Liebman, Katherine M.; Williams, Rachel; Kumar, Amrendra; Chim-Ong, Anongruk; Cui, Liwang; Orena, Stephen; Assimwe, Jackson; Tibagambirwa, Innocent; Byaruhanga, Oswald; Angutoko, Patrick; Legac, Jennifer; Kreutzfeld, Oriana; Rosenthal, Philip J.; Cooper, Roland A.; Nilsen, Aaron; Riscoe, Michael K.; Roth, Alison; Kancharla, Papireddy; Kelly, Jane X.
Tambjamines as Fast-Acting Multistage Antimalarials
ACS INFECTIOUS DISEASES
IF3.8
2024-11-110
PRE
Kumar, Amrendra; Li, Yuexin; Dodean, Rozalia A.; Roth, Alison; Caridha, Diana; Madejczyk, Michael S.; Jin, Xiannu; Dennis, William E.; Lee, Patricia J.; Pybus, Brandon S.; Martin, Monica; Pannone, Kristina; Dinh, Hieu T.; Blount, Cameron; Chetree, Ravi; Deluca, Jesse; Evans, Martin; Nadeau, Robert; Vuong, Chau; Leed, Susan; Black, Chad; Sousa, Jason; Nolan, Christina; Ceja, Frida G.; Rasmussen, Stephanie A.; Tumwebaze, Patrick K.; Rosenthal, Philip J.; Cooper, Roland A.; Rottmann, Matthias; Orjuela-Sanchez, Pamela; Meister, Stephan; Winzeler, Elizabeth A.; Delves, Michael J.; Matthews, Holly; Baum, Jake; Kirby, Robert W.; Burrows, Jeremy N.; Duffy, James; Peyton, David H.; Reynolds, Kevin A.; Kelly, Jane X.; Kancharla, Papireddy
3-Position Biaryl Endochin-like Quinolones with Enhanced Antimalarial Performance
ACS INFECTIOUS DISEASES
IF3.8
2024-06-110
PRE
Pou, Sovitj; Winter, Rolf W.; Dodean, Rozalia A.; Liebman, Katherine; Li, Yuexin; Mather, Michael W.; Nepal, Binod; Nilsen, Aaron; Handford, Mason J.; Riscoe, Teresa M.; Laxson, Sydney; Kirtley, Payton J.; Aleshnick, Maya; Zakharov, Lev N.; Kelly, Jane X.; Smilkstein, Martin J.; Wilder, Brandon K.; Kortagere, Sandhya; Vaidya, Akhil B.; Alday, P. Holland; Doggett, J. Stone; Riscoe, Michael K.
Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-05-092
OA
Kancharla, Papireddy; Ortiz, Diana; Fargo, Corinne M.; Zhang, Xiaowei; Li, Yuexin; Sanchez, Marco; Kumar, Amrendra; Yeluguri, Monish; Dodean, Rozalia A.; Caridha, Diana; Madejczyk, Michael S.; Martin, Monica; Jin, Xiannu; Blount, Cameron; Chetree, Ravi; Pannone, Kristina; Dinh, Hieu T.; DeLuca, Jesse; Evans, Martin; Nadeau, Robert; Vuong, Chau; Leed, Susan; Dennis, William E.; Roncal, Norma; Pybus, Brandon S.; Lee, Patricia J.; Roth, Alison; Reynolds, Kevin A.; Kelly, Jane X.; Landfear, Scott M.
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-05-118
OAAI
Kancharla, Papireddy; Dodean, Rozalia A.; Li, Yuexin; Pou, Sovitj; Pybus, Brandon; Melendez, Victor; Read, Lisa; Bane, Charles E.; Vesely, Brian; Kreishman-Deitrick, Mara; Black, Chad; Li, Qigui; Sciotti, Richard J.; Olmeda, Raul; Luong, Thu-Lan; Gaona, Heather; Potter, Brittney; Sousa, Jason; Marcsisin, Sean; Caridha, Diana; Xie, Lisa; Chau Vuong; Zeng, Qiang; Zhang, Jing; Zhang, Ping; Lin, Hsiuling; Butler, Kirk; Roncal, Norma; Gaynor-Ohnstad, Lacy; Leed, Susan E.; Nolan, Christina; Ceja, Frida G.; Rasmussen, Stephanie A.; Tumwebaze, Patrick K.; Rosenthal, Philip J.; Mu, Jianbing; Bayles, Brett R.; Cooper, Roland A.; Reynolds, Kevin A.; Smilkstein, Martin J.; Riscoe, Michael K.; Kelly, Jane X.
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-03-1014
OAAI
Dodean, Rozalia A.; Kancharla, Papireddy; Li, Yuexin; Melendez, Victor; Read, Lisa; Bane, Charles E.; Vesely, Brian; Kreishman-Deitrick, Mara; Black, Chad; Li, Qigui; Sciotti, Richard J.; Olmeda, Raul; Thu-Lan Luong; Gaona, Heather; Potter, Brittney; Sousa, Jason; Marcsisin, Sean; Caridha, Diana; Xie, Lisa; Vuong, Chau; Zeng, Qiang; Zhang, Jing; Zhang, Ping; Lin, Hsiuling; Butler, Kirk; Roncal, Norma; Gaynor-Ohnstad, Lacy; Leed, Susan E.; Nolan, Christina; Huezo, Stephanie J.; Rasmussen, Stephanie A.; Stephens, Melissa T.; Tan, John C.; Cooper, Roland A.; Smilkstein, Martin J.; Pou, Sovitj; Winter, Rolf W.; Riscoe, Michael K.; Kelly, Jane X.
Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria
ACS INFECTIOUS DISEASES
IF3.8
2017-09-2741
OAAI
Frueh, Lisa; Li, Yuexin; Mather, Michael W.; Li, Qigui; Pou, Sovitj; Nilsen, Aaron; Winter, Rolf W.; Forquer, Isaac P.; Pershing, April M.; Xie, Lisa H.; Smilkstein, Martin J.; Caridha, Diana; Koop, Dennis R.; Campbell, Robert F.; Sciotti, Richard J.; Kreishman-Deitrick, Mara; Kelly, Jane X.; Vesely, Brian; Vaidya, Akhil B.; Riscoe, Michael K.

研究方向

暂未获取到该数据
M
Michael K. Riscoe
H 指数:39论文数:131被引数:5,721
Y
Yuexin Li
H 指数:36论文数:213被引数:4,509
R
Rozalia A. Dodean
H 指数:16论文数:48被引数:940
P
Papireddy Kancharla
H 指数:13论文数:29被引数:740
R
Rolf W. Winter
H 指数:39论文数:310被引数:4,866
S
Sovitj Pou
H 指数:33论文数:177被引数:5,438
K
Kevin A. Reynolds
H 指数:43论文数:156被引数:5,157
M
Martin J. Smilkstein
H 指数:26论文数:54被引数:4,885
D
Diana Caridha
H 指数:23论文数:61被引数:1,666
A
Aaron Nilsen
H 指数:28论文数:75被引数:2,474