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Sofia Origanti

saint louis university

H指数:10

被引数:478

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Mechanism of RPA phosphocode priming and tuning by CDK1/WEE1 signaling circuit

RPA磷酸化密码的CDK1/WEE1信号通路介导的启动与调控机制

Nature Communications

IF15.7

2025-12-090

OAAI

Sequestration of ribosomal subunits as inactive 80S by targeting eIF6 limits mitotic exit and cancer progression

NUCLEIC ACIDS RESEARCH

IF13.1

2024-12-270

OAAI

Partial wrapping of single-stranded DNA by replication protein A and modulation through phosphorylation

NUCLEIC ACIDS RESEARCH

IF13.1

2024-07-110

OAAI

Targeting eIF6 to modulate ribosomal subunit association dynamics in cancers

CANCER RESEARCH

IF16.6

2024-03-220

PRE

An Aurora B-RPA signaling axis secures chromosome segregation fidelity

NATURE COMMUNICATIONS

IF15.7

2023-05-256

OAAI

Targeting the eIF6 and 60S ribosomal subunit interaction interface in cancers

CANCER RESEARCH

IF16.6

2023-04-040

PRE

Site-specific labeling of SBDS to monitor interactions with the 60S ribosomal subunit

IF4.3

2023-03-012

OAAI

Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit

NUCLEIC ACIDS RESEARCH

IF13.1

2023-01-183

OAAI

The flexible N-terminus of BchL autoinhibits activity through interaction with its [4Fe-4S] cluster and released upon ATP binding

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-016

OAAI

Regulation of eukaryotic translation initiation factor 6 dynamics through multisite phosphorylation by GSK3

GSK3通过多位点磷酸化调控真核翻译起始因子6动力学

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-09-019

OAAI

Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

NUCLEIC ACIDS RESEARCH

IF13.1

2017-07-1238

OAAI

Destabilization of the ornithine decarboxylase mRNA transcript by the RNA-binding protein tristetraprolin

RNA结合蛋白tristetranprolin对鸟氨酸脱羧酶mRNA转录物的去稳定化

IF2.4

2016-05-195

OA

Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells

在正常和肿瘤细胞的DNA损伤反应中，Chk1抑制与p53和/或p21丢失的合成致死率

IF7.3

2012-03-1966

OAAI

Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells

BIOCHEMICAL JOURNAL

IF4.3

2012-01-2732

OAAI

Ras transformation of RIE-1 cells activates cap-independent translation of ornithine decarboxylase: Regulation by the Raf/MEK/ERK and phosphatidylinositol 3-kinase pathways

CANCER RESEARCH

IF16.6

2007-05-1744

OAAI

Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis

IF2.9

2006-01-0740

OAAI