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林

林秀坤 (Xiukun Lin)

chinese academy of sciences

H指数:39

被引数:4,867

个人简介

教授、博士生导师。1996年获中国医学科学院、中国协和医科大学博士学位；1996年至2002年在美国耶鲁大学作为博士后助理教授从事抗肿瘤机理研究；2003年回国，在海洋研究所任研究员；2016年进入西南医科大学。参入编写英文专著多部，获中国国内外发明专利18项，发表SCI论文近百篇。现承担国家自然科学基金课题、国家创新药物重大专项课题等多项国家级研究课题。

教育背景

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工作经历

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荣誉奖项

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Recent progress of protein kinase inhibitors derived from marine peptides for developing anticancer gents (vol 124 ,111411 , 2024)

CELLULAR SIGNALLING

IF3.7

2024-12-010

PRE

Recent progress of protein kinase inhibitors derived from marine peptides for developing anticancer agents

海洋肽衍生的蛋白激酶抑制剂用于开发抗癌药物的最新进展

CELLULAR SIGNALLING

IF3.7

2024-12-011

PRE

Hypnea musciformis Seaweed Extract Protected Human Mesenchymal Stem Cells From Oxidative Stress Through NRF2 Activation

FOOD SCIENCE & NUTRITION

IF3.8

2024-11-270

OA

LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines

CELL DEATH & DISEASE

IF9.6

2023-10-165

OAAI

Transcriptome and proteome analysis reveals the anti-cancer properties of Hypnea musciformis marine macroalga extract in liver and intestinal cancer cells

IF4.3

2023-07-319

OAAI

Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair

BIOENGINEERING & TRANSLATIONAL MEDICINE

IF5.7

2023-03-288

OAAI

Alpinia katsumadai Hayata induces growth inhibition and autophagy-related apoptosis by regulating the AMPK and Akt/mTOR/p70S6K signaling pathways in cancer cells

ONCOLOGY REPORTS

IF3.9

2022-06-2013

OAAI

Targeting NQO1/GPX4-mediated ferroptosis by plumbagin suppresses in vitro and in vivo glioma growth

BRITISH JOURNAL OF CANCER

IF6.8

2022-04-0865

OA

Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis

PHYTOTHERAPY RESEARCH

IF6.3

2021-11-3030

PRE

Protein kinases as therapeutic targets to develop anticancer drugs with natural alkaloids

FRONTIERS IN BIOSCIENCE-LANDMARK

IF3.1

2021-11-304

OA

Marine Bromophenol Bis(2,3,6-Tribromo-4,5-Dihydroxybenzyl)ether Inhibits Angiogenesis in Human Umbilical Vein Endothelial Cells and Reduces Vasculogenic Mimicry in Human Lung Cancer A549 Cells

IF5.4

2021-11-169

OAAI

Cucurbitacin mediated regulation of deregulated oncogenic signaling cascades and non-coding RNAs in different cancers: Spotlight on JAK/ STAT, Wnt/β-catenin, mTOR, TRAIL-mediated pathways

SEMINARS IN CANCER BIOLOGY

IF15.7

2021-08-0126

PREAI

Exosomes-coated bcl-2 siRNA inhibits the growth of digestive system tumors both in vitro and in vivo

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2020-10-0150

PREAI

Progress of Bromophenols in Marine Algae from 2011 to 2020: Structure, Bioactivities, and Applications

IF5.4

2020-08-0435

OAAI

A tropomyosin-like Meretrix meretrix Linnaeus polypeptide inhibits the proliferation and metastasis of glioma cells via microtubule polymerization and FAK/Akt/MMPs signaling

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2020-02-0116

PREAI

Teratogenic jervine increases the activity of doxorubicin in MCF-7/ADR cells by inhibiting ABCB1

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2019-09-017

OAAI

Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway

PHYTOTHERAPY RESEARCH

IF6.3

2019-04-1634

PREAI

Regulation of signaling pathways by β-elemene in cancer progression and metastasis

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2019-03-2526

PREAI

Active components of Alpinia katsumadai-induced cell apoptosis and autophagy in human pancreatic cancer cells

CANCER RESEARCH

IF16.6

2018-07-010

PRE

Cloning, expression and purification of Cionasavignyi polypeptide CS5931 and its antitumor activity

CANCER RESEARCH

IF16.6

2018-07-010

PRE