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黄河 封面图

黄河 (He Huang)

State Key Laboratory of Chemical Biology

50H指数
213论文数
1.4W被引数
收录论文 93
发表时间
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Integrative multi-omics of esophageal squamous cell carcinoma reveals immune alterations and lactylation-driven mechanisms in metastatic progression食管鳞状细胞癌的整合多组学分析揭示了转移进展中的免疫改变及乳酰化驱动的机制
errMolecular Cancer
IF33.9
err2026-07-28
err0
errOAAI
errYanan Pang; Ye Gao; Guobin Liu; Jingxiang Zhao; Han Lin; Yilin Wang; Lei Xin; Wei Wang; Yan Bian; Yunfei Jiao; Qiuxin Li; Zengjun Li; Zhaoshen Li; He Huang; Luowei Wang
err分享
err收藏
Lysine pyruvylation couples glycolytic flux to epigenetic regulation赖氨酸丙酮酰化将糖酵解流量与表观遗传调控相偶联
errNature Metabolism
IF20.8
err2026-07-03
err0
PREAI
errXiaohan Song; Panpan Peng; Haonan Zheng; Yanan Zheng; Qianjing Wang; Yu Ge; Doudou Tan; Lu Chen; Xinbo Wang; He Huang
err分享
err收藏
Comprehensive Proteomic Profiling Reveals Molecular Mechanisms Mediating Chemoradiotherapy Efficacy in Lung Cancer综合蛋白质组学分析揭示介导肺癌放化疗疗效的分子机制
errJournal of Proteome Research
IF3.6
err2026-06-02
err0
PREAI
errWeiwei Ouyang; Yixuan Wang; Jianghua Yang; Dongdong Cao; Qianjing Wang; Yuxi Luo; Chuan Tian; He Huang; Xinbo Wang
err分享
err收藏
Lactylome Reprogramming Mediates Therapeutic Response and Adaptation to Neoadjuvant Chemotherapy in Esophageal Squamous Cell CarcinomaLactylome重编程介导了食管鳞状细胞癌对新辅助化疗的治疗反应和适应性。
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2026-04-01
err0
errOAAI
errPanpan Peng; Xinyi Cen; Tianxiao Wang; Shuang Wei; Xinbo Wang; Xuelian Ren; Cong Yan; Yongjun Zhu; Qian Niu; Lu Chen; Qi Mei; Xiansheng Liu; Qunyi Li; He Huang
err分享
err收藏
Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation有效和选择性的LSD1抑制剂DC551040揭示了AML的有希望的联合治疗，并深入了解表观遗传失调
errSignal Transduction and Targeted Therapy
IF52.7
err2026-03-23
err0
errOAAI
errJiang Wang; Hanlin Wang; Runhua Du; Chunpu Li; Mingbo Su; Shuni Wang; Weijuan Kan; Guobin Liu; Yu Zhang; Xiaobei Hu; Feng Gao; Gaoya Xu; Cong Li; Wei Zhu; Yunfei Ye; Li Sheng; Yuqiang Shi; Yingying Shao; Jiangzhou Song; Yuxian Wang; Bo Wang; Yubo Zhou; He Huang; Jia Li; Hong Liu
err分享
err收藏
Covalent capture and genetic code expansion enables chemoproteomic profiling and functional characterization of lysine acetoacetylation共价捕获和遗传密码扩展实现了乙酰乙酸化赖氨酸的化学生物学谱分析和功能表征
errScience Advances
IF12.5
err2026-02-20
err0
errOAAI
errXiaohan Song; Yuhan Lu; Xinlong Guo; Yanan Zheng; He Huang
err分享
err收藏
Chemical Proteomic Profiling of Lysine Benzoylation赖氨酸苯甲酰化的化学蛋白质组学分析
errJournal of Proteome Research
IF3.6
err2026-02-04
err0
PREAI
errXiaohan Song; Yuhan Lu; Panpan Peng; Binjing Chen; He Huang
err分享
err收藏
Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells定量蛋白质组学揭示了赖氨酸乳酰化在来那度胺耐药性中的作用机制（多发性骨髓瘤细胞）
errACS Chemical Biology
IF3.8
err2025-07-01
err0
PREAI
errXinlong Guo; Xuelian Ren; Cong Yan; He Huang
err分享
err收藏
SQSTM1/p62 Orchestrates Skin Aging via USP7 DegradationSQSTM1/p62 通过 USP7 降解调控皮肤衰老
errAGING CELL
IF7.1
err2025-05-08
err0
errOAAI
errChen, L; Wang, XP; Wang, YC; Yao, QX; Liu, YY; Zhu, YC; Huang, H; Yang, HD; Yang, Y; He, Y; Qiang, L
err分享
err收藏
Deciphering the Metabolic Impact and Clinical Relevance of N-Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling通过全面的糖组蛋白组学分析，解读N-糖基化在结直肠癌中的代谢影响和临床相关性。
errADVANCED SCIENCE
IF14.1
err2025-04-26
err0
errOAAI
errLiu, GB; Chen, L; Zhao, JX; Jiang, Y; Guo, YR; Mao, X; Ren, XL; Liu, K; Mei, Q; Li, QY; Huang, H
err分享
err收藏
Asymmetric macrocyclization enabled by Rh(III)-catalyzed C-H activation: Enantioenriched macrocyclic inhibitor of Zika virus infectionRh(III) 催化的c-h活化实现的不对称大环化: 寨卡病毒感染的对映体富集大环抑制剂
errCHINESE CHEMICAL LETTERS
IF8.9
err2024-11-01
err1
PREAI
errChen, Chao; Yu, Wenwen; Huang, Guangen; Ren, Xuelian; Chen, Xiangli; Li, Yixin; Liang, Shenggui; Xu, Mengmeng; Zheng, Mingyue; Yang, Yaxi; Huang, He; Tang, Wei; Zhou, Bing
err分享
err收藏
Controlled Reversible N-Terminal Modification of Peptides and Proteins肽和蛋白质的受控可逆N末端修饰
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-08-15
err1
PREAI
errLin, Zeng; Liu, Bo; Lu, Mengru; Wang, Yongqin; Ren, Xuelian; Liu, Zhaoxi; Luo, Caili; Shi, Wei; Zou, Xiangman; Song, Xiaohan; Tang, Feng; Huang, He; Huang, Wei
err分享
err收藏
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-06-24
err2
PREAI
errLou, Jianfeng; Zhou, Qianqian; Lyu, Xilin; Cen, Xinyi; Liu, Chen; Yan, Ziqin; Li, Yan; Tang, Haotian; Liu, Qiupei; Ding, Jian; Lu, Ye; Huang, He; Xie, Hua; Zhao, Yujun
err分享
err收藏
Exploring the Molecular Therapeutic Mechanisms of Gemcitabine through Quantitative Proteomics
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2024-06-04
err1
PREAI
errJiang, Yue; Ren, Xuelian; Zhao, Jing; Liu, Guobin; Liu, Fangfang; Guo, Xinlong; Hao, Ming; Liu, Hong; Liu, Kun; Huang, He
err分享
err收藏
Exploring the mechanism of contact-dependent cell-cell communication on chemosensitivity based on single-cell high-throughput drug screening platform
errTALANTA
IF6.1
err2024-06-01
err0
PREAI
errJiang, Yue; Ren, Xuelian; Liu, Guobin; Chen, Shulei; Hao, Ming; Deng, Xinran; Huang, He; Liu, Kun
err分享
err收藏
Quantitative Proteomics Reveal the Role of Matrine in Regulating Lipid Metabolism
errACS OMEGA
IF4.3
err2024-05-29
err1
errOAAI
errFeng, Huixu; Liu, Guobin; Li, Luhan; Ren, Xuelian; Jiang, Yue; Hou, Wanting; Liu, Ruilong; Liu, Kun; Liu, Hong; Huang, He
err分享
err收藏
Advancing In-Depth N-Terminomics Detection with a Cleavable 2-Pyridinecarboxyaldehyde Probe
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-02-29
err3
PREAI
errSong, Xiaohan; Ren, Xuelian; Mei, Qi; Liu, Hong; Huang, He
err分享
err收藏
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-18
err3
PREAI
errRao, Danni; Yang, Tao; Feng, Huixu; An, Qi; Zhang, Shaofeng; Yu, Jinghua; Ren, Xuelian; Diao, Xingxing; Huang, He; Tang, Wei; Xu, Shilin
err分享
err收藏
HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation
errCELL DISCOVERY
IF12.5
err2023-08-15
err17
errOAAI
errLi, Jialun; Lu, Lu; Liu, Lingling; Ren, Xuelian; Chen, Jiwei; Yin, Xingzhi; Xiao, Yanhui; Li, Jiwen; Wei, Gang; Huang, He; Wei, Wei; Wong, Jiemin
err分享
err收藏
Identification of Histone Lysine Acetoacetylation as a Dynamic Post-Translational Modification Regulated by HBO1组蛋白赖氨酸乙酰乙酰化作为HBO1调控的动态翻译后修饰的鉴定
errADVANCED SCIENCE
IF14.1
err2023-06-29
err8
errOAAI
errGao, Yan; Sheng, Xinlei; Tan, Doudou; Kim, SunJoo; Choi, Soyoung; Paudel, Sanjita; Lee, Taeho; Yan, Cong; Tan, Minjia; Kim, Kyu Min; Cho, Sam Seok; Ki, Sung Hwan; Huang, He; Zhao, Yingming; Lee, Sangkyu
err分享
err收藏

研究方向

蛋白质新型翻译后修饰关键调控因子疾病演进机制代谢调节天然产物化学
合作学者
合作期刊
C
C. David Allis
H 指数: 164 · 论文数: 433
R
Robert G. Roeder
H 指数: 162 · 论文数: 679
李
李永舫 (Yongfang Li)
H 指数: 155 · 论文数: 1.4K
P
Paolo Sassone‐Corsi
H 指数: 132 · 论文数: 543
樊
樊嘉 (Jia Fan)
H 指数: 126 · 论文数: 1.5K
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