William M. Shafer - Publications, H-index & Citations

William M. Shafer

Atlanta VA Medical Center

59H指数

263论文数

1.2W被引数

收录论文 69

发表时间

Activity of Corallopyronin A Against ESKAPEE Pathogens: Potential and Translational Implications 珊瑚珊瑚菌素A对ESKAPEE病原体的活性：潜力和转化意义

Antibiotics-Basel

IF4.6

2026-08-16

OAAI

Jennifer M. Colquhoun; Kara W. Marshall; Miriam Grosse; Birthe Sandargo; Kenneth Pfarr; Andrea Schiefer; Achim Hoerauf; William M. Shafer; Philip N. Rather

The impact of dynamic mucosal baseline immune states on C. muridarum and N. gonorrhoeae infection outcomes in a murine menstruation model

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Vidal, Paola; Varunghese, Richa S.; Cendoya, Sofia Rose; Shafer, William Maurice; Swaims Kohlmeier, Alison

Structural and functional diversity of Resistance-Nodulation-Division (RND) efflux pump transporters with implications for antimicrobial resistance

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

IF7.8

2024-09-26

PREAI

Kavanaugh, Logan G.; Dey, Debayan; Shafer, William M.; Conn, Graeme L.

Experimental genital tract infection demonstrates Neisseria gonorrhoeae MtrCDE efflux pump is not required for in vivo human infection and identifies gonococcal colonization bottleneck

PLOS PATHOGENS

IF4.9

2024-09-25

OAAI

Waltmann, Andreea; Balthazar, Jacqueline T.; Begum, Afrin A.; Hua, Nancy; Jerse, Ann E.; Shafer, William M.; Hobbs, Marcia M.; Duncan, Joseph A.

Transcriptional responses of Neisseria gonorrhoeae to glucose and lactate: implications for resistance to oxidative damage and biofilm formation

MBIO

IF4.7

2024-08-14

OAAI

Ayala, Julio C.; Balthazar, Jacqueline T.; Shafer, William M.

A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase (vol 12, pg e00560, 2024)一种基于实验室的预测途径，用于发展淋病奈瑟菌对细菌RNA聚合酶抑制剂corallopyronin A的高水平抗性 (vol 12，pg e00560，2024)

MICROBIOLOGY SPECTRUM

IF3.8

2024-08-06

OAAI

Balthazar, Jacqueline T.; Golparian, Daniel; Unemo, Magnus; Read, Timothy D.; Grosse, Miriam; Stadler, Marc; Pfarr, Kenneth; Schiefer, Andrea; Hoerauf, Achim; Edwards, Jennifer L.; Vassylyev, Dmitry G.; Shafer, William M.

A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase 基于实验室的预测途径，用于发展淋病奈瑟菌对细菌RNA聚合酶抑制剂corallopyronin A的高水平抗性

MICROBIOLOGY SPECTRUM

IF3.8

2024-06-04

OAAI

Ensuring a sustained workforce to combat antibiotic resistance in the 21st century: the critical need for training the next-gen of scientists at the pre-doctoral level

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-04-19

PREAI

Shafer, William M.; Conn, Graeme L.

Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

NATURE COMMUNICATIONS

IF15.7

2024-02-07

OAAI

Hooks, Grace M.; Ayala, Julio C.; Holley, Concerta L.; Dhulipala, Vijaya; Beggs, Grace A.; Perfect, John R.; Schumacher, Maria A.; Shafer, William M.; Brennan, Richard G.

Transcriptional activation of ompA in Neisseria gonorrhoeae mediated by the XRE family member protein NceR XRE家族成员蛋白NceR介导的淋病奈瑟菌中ompA的转录激活

MBIO

IF4.7

2023-06-30

OAAI

Holley, Concerta L. L.; Dhulipala, Vijaya; Maurakis, Stavaros A. A.; Greenawalt, Ashley Nicole; Read, Timothy D. D.; Cornelissen, Cynthia N. N.; Shafer, William M. M.

High-level in vitro resistance to gentamicin acquired in a stepwise manner in Neisseria gonorrhoeae

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

IF3.6

2023-05-30

PREAI

Golparian, Daniel; Jacobsson, Susanne; Holley, Concerta L.; Shafer, William M.; Unemo, Magnus

Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

MICROBIOLOGY SPECTRUM

IF3.8

2022-10-26

OAAI

Lyu, Meinan; Ayala, Julio C.; Chirakos, Isabella; Su, Chih-Chia; Shafer, William M.; Yu, Edward W.

Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A

MSPHERE

IF3.1

2022-10-26

OAAI

Edwards, Jennifer L.; Balthazar, Jacqueline T.; Esposito, Danillo L. A.; Ayala, Julio C.; Schiefer, Andrea; Pfarr, Kenneth; Hoerauf, Achim; Alt, Silke; Hesterkamp, Thomas; Grosse, Miriam; Stadler, Marc; Golparian, Daniel; Unemo, Magnus; Read, Timothy D.; Shafer, William M.

A Single Amino Acid Substitution in Elongation Factor G Can Confer Low-Level Gentamicin Resistance in Neisseria gonorrhoeae 延伸因子G中的单个氨基酸取代可赋予淋病奈瑟氏球菌低水平的庆大霉素抗性

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2022-05-17

OAAI

Holley, Concerta L.; Dhulipala, Vijaya; Balthazar, Jacqueline T.; Le Van, Adriana; Begum, Afrin A.; Chen, Shao-Chun; Read, Timothy D.; Matoga, Mitch; Hoffman, Irving F.; Golparian, Daniel; Unemo, Magnus; Jerse, Ann E.; Shafer, William M.

Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess a mtrR Promoter Mutation That Decreases Antibiotic Susceptibility

MBIO

IF4.7

2022-04-26

OAAI

Ayala, Julio C.; Schmerer, Matthew W.; Kersh, Ellen N.; Unemo, Magnus; Shafer, William M.

Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations

NUCLEIC ACIDS RESEARCH

IF13.1

2021-03-30

OAAI

Beggs, Grace A.; Ayala, Julio C.; Kavanaugh, Logan G.; Read, Timothy D.; Hooks, Grace M.; Schumacher, Maria A.; Shafer, William M.; Brennan, Richard G.

The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae

PLOS PATHOGENS

IF4.9

2020-12-08

OAAI

Leduc, Isabelle; Connolly, Kristie L.; Begum, Afrin; Underwood, Knashka; Darnell, Stephen; Shafer, William M.; Balthazar, Jacqueline T.; Macintyre, Andrew N.; Sempowski, Gregory D.; Duncan, Joseph A.; Little, Marguerite B.; Rahman, Nazia; Garges, Eric C.; Jerse, Ann E.

Drug Targeting a Gonococcal Virulence Factor Exploits Host Antimicrobial Peptides in Clearance of Infection

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2020-07-21

OAAI

Shafer, William M.

Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance

MBIO

IF4.7

2020-06-30

OAAI

Lyu, Meinan; Moseng, Mitchell A.; Reimche, Jennifer L.; Holley, Concerta L.; Dhulipala, Vijaya; Su, Chih-Chia; Shafer, William M.; Yu, Edward W.