George K. Christophides - Publications, H-index & Citations

George K. Christophides

imperial college london

62H指数

210论文数

1.6W被引数

收录论文 67

发表时间

Oocyst: knowns and unknowns about the lengthiest life stage of the malaria parasite 疟原虫最长生活史阶段：已知与未知

Open Biology

IF3.6

2026-04-22

PREAI

Bailey, Alexander J.; Vlachou, Dina; Christophides, George K.

Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania 具有基因驱动能力的蚊子抑制坦桑尼亚患者来源的疟疾

Nature

IF48.5

2025-12-10

OAAI

Tibebu Habtewold; Dickson Wilson Lwetoijera; Astrid Hoermann; Rajabu Mashauri; Fatuma Matwewe; Rehema Mwanga; Prisca Kweyamba; Gilbert Maganga; Beatrice Philip Magani; Rachel Mtama; Moze Ally Mahonje; Mgeni Mohamed Tambwe; Felista Tarimo; Pratima R. Chennuri; Julia A. Cai; Giuseppe Del Corsano; Paolo Capriotti; Peter Sasse; Jason Moore; Douglas Hudson; Alphaxard Manjurano; Brian Tarimo; Dina Vlachou; Sarah Moore; Nikolai Windbichler; George K. Christophides

The nanosd integral gene drive enables population modification of the malaria vector Anopheles gambiae 纳米SD整合基因驱动系统使疟疾媒介按蚊（Anopheles gambiae）的种群改造成为可能。

G3-GENES GENOMES GENETICS

IF2.2

2025-11-01

OAAI

Yen, Pei-Shi; Verkuijl, Sebald A. N. R.; Capriotti, Paolo; Del Corsano, Giuseppe; Yee, Calvin Kim Guan; Hoermann, Astrid; Inghilterra, Maria Grazia; Aramburu-Gonzalez, Irati; Khan, Moeez A.; Vlachou, Dina; Christophides, George K.; Windbichler, Nikolai

Nanobody-mediated targeting of Plasmodium falciparum PfPIMMS43 can block malaria transmission in mosquitoes 纳米抗体介导的Plasmodium falciparum PfPIMMS43靶向作用可以阻断蚊媒疟疾传播

COMMUNICATIONS BIOLOGY

IF5.1

2025-04-30

OAAI

Ukegbu, Chiamaka Valerie; Mohamed, Mgeni; Hoermann, Astrid; Qin, Yuyan; Kweyamba, Prisca A.; Lwetoijera, Dickson Wilson; Windbichler, Nikolai; Moore, Sarah; Christophides, George K.; Vlachou, Dina

A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184 一种用于疟疾控制的抑制-改造基因驱动系统，靶向高度保守的RNA基因mir-184

NATURE COMMUNICATIONS

IF15.7

2025-04-25

OAAI

Verkuijl, Sebald A. N.; Del Corsano, Giuseppe; Capriotti, Paolo; Yen, Pei-Shi; Inghilterra, Maria Grazia; Selvaraj, Prashanth; Hoermann, Astrid; Martinez-Sanchez, Aida; Ukegbu, Chiamaka Valerie; Kebede, Temesgen M.; Vlachou, Dina; Christophides, George K.; Windbichler, Nikolai

Malaria vectors with leaky guts Vector biology 疟疾媒介具有渗漏性肠道媒介生物学

NATURE MICROBIOLOGY

IF19.4

2025-03-20

PREAI

Christophides, George K.

Immune interactions between mosquitoes and microbes during midgut colonization

CURRENT OPINION IN INSECT SCIENCE

IF4.8

2024-06-01

OAAI

Cai, Julia A.; Christophides, George K.

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023 VEuPathDB: 真核病原体，载体和宿主生物信息学资源中心2023年

NUCLEIC ACIDS RESEARCH

IF13.1

2023-11-11

OAAI

Alvarez-Jarreta, Jorge; Amos, Beatrice; Aurrecoechea, Cristina; Bah, Saikou; Barba, Matthieu; Barreto, Ana; Basenko, Evelina Y.; Belnap, Robert; Blevins, Ann; Boehme, Ulrike; Brestelli, John; Brown, Stuart; Callan, Danielle; Campbell, Lahcen, I; Christophides, George K.; Crouch, Kathryn; Davison, Helen R.; Debarry, Jeremy D.; Demko, Richard; Doherty, Ryan; Duan, Yikun; Dundore, Walter; Dyer, Sarah; Falke, Dave; Fischer, Steve; Gajria, Bindu; Galdi, Daniel; Giraldo-Calderon, Gloria, I; Harb, Omar S.; Harper, Elizabeth; Helb, Danica; Howington, Connor; Hu, Sufen; Humphrey, Jay; Iodice, John; Jones, Andrew; Judkins, John; Kelly, Sarah A.; Kissinger, Jessica C.; Kittur, Nupur; Kwon, Dae Kun; Lamoureux, Kristopher; Li, Wei; Lodha, Disha; Maccallum, Robert M.; Maslen, Gareth; Mcdowell, Mary Ann; Myers, Jeremy; Nural, Mustafa Veysi; Roos, David S.; Rund, Samuel S. C.; Shanmugasundram, Achchuthan; Sitnik, Vasily; Spruill, Drew; Starns, David; Tomko, Sheena Shah; Wang, Haiming; Warrenfeltz, Susanne; Wieck, Robert; Wilkinson, Paul A.; Zheng, Jie

Intracellular Plasmodium aquaporin 2 is important for sporozoite production in the mosquito vector and malaria transmission 胞内疟原虫水通道蛋白2对蚊媒中的子孢子产生和疟疾传播很重要

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-10-26

OAAI

Bailey, Alexander J.; Ukegbu, Chiamaka Valerie; Giorgalli, Maria; Besson, Tanguy Rene Balthazar; Christophides, George K.; Vlachou, Dina

Climate change and human health in the Eastern Mediterranean and middle east: Literature review, research priorities and policy suggestions

ENVIRONMENTAL RESEARCH

IF7.7

2023-01-01

OAAI

Neira, Marco; Erguler, Kamil; Ahmady-Birgani, Hesam; AL-Hmoud, Nisreen DaifAllah; Fears, Robin; Gogos, Charalambos; Hobbhahn, Nina; Koliou, Maria; Kostrikis, Leondios G.; Lelieveld, Jos; Majeed, Azeem; Paz, Shlomit; Rudich, Yinon; Saad-Hussein, Amal; Shaheen, Mohammed; Tobias, Aurelio; Christophides, George

Gene drive mosquitoes can aid malaria elimination by retarding Plasmodium sporogonic development

SCIENCE ADVANCES

IF12.5

2022-09-23

OAAI

Hoermann, Astrid; Habtewold, Tibebu; Selvaraj, Prashanth; Del Corsano, Giuseppe; Capriotti, Paolo; Inghilterra, Maria Grazia; Kebede, Temesgen M.; Christophides, George K.; Windbichler, Nikolai

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

NUCLEIC ACIDS RESEARCH

IF13.1

2021-10-28

247

OAAI

Amos, Beatrice; Aurrecoechea, Cristina; Barba, Matthieu; Barreto, Ana; Basenko, Evelina Y.; Bazant, Wojciech; Belnap, Robert; Blevins, Ann S.; Bohme, Ulrike; Brestelli, John; Brunk, Brian P.; Caddick, Mark; Callan, Danielle; Campbell, Lahcen; Christensen, Mikkel B.; Christophides, George K.; Crouch, Kathryn; Davis, Kristina; DeBarry, Jeremy; Doherty, Ryan; Duan, Yikun; Dunn, Michael; Falke, Dave; Fisher, Steve; Flicek, Paul; Fox, Brett; Gajria, Bindu; Giraldo-Calderon, Gloria, I; Harb, Omar S.; Harper, Elizabeth; Hertz-Fowler, Christiane; Hickman, Mark J.; Howington, Connor; Hu, Sufen; Humphrey, Jay; Iodice, John; Jones, Andrew; Judkins, John; Kelly, Sarah A.; Kissinger, Jessica C.; Kwon, Dae Kun; Lamoureux, Kristopher; Lawson, Daniel; Li, Wei; Lies, Kallie; Lodha, Disha; Long, Jamie; MacCallum, Robert M.; Maslen, Gareth; McDowell, Mary Ann; Nabrzyski, Jaroslaw; Roos, David S.; Rund, Samuel S. C.; Schulman, Stephanie Wever; Shanmugasundram, Achchuthan; Sitnik, Vasily; Spruill, Drew; Starns, David; Stoeckert, Christian J.; Tomko, Sheena Shah; Wang, Haiming; Warrenfeltz, Susanne; Wieck, Robert; Wilkinson, Paul A.; Xu, Lin; Zheng, Jie

Unravelling population structure heterogeneity within the genome of the malaria vector Anopheles gambiae

BMC GENOMICS

IF3.7

2021-06-08

OAAI

Campos, Melina; Rona, Luisa D. P.; Willis, Katie; Christophides, George K.; MacCallum, Robert M.

Anopheles coluzzii stearoyl-CoA desaturase is essential for adult female survival and reproduction upon blood feeding

PLOS PATHOGENS

IF4.9

2021-05-20

OAAI

Ferdous, Zannatul; Fuchs, Silke; Behrends, Volker; Trasanidis, Nikolaos; Waterhouse, Robert M.; Vlachou, Dina; Christophides, George K.

Converting endogenous genes of the malaria mosquito into simple non-autonomous gene drives for pope ion replacement

ELIFE

IF0

2021-04-13

OAAI

Hoermann, Astrid; Tapanelli, Sofia; Capriotti, Paolo; Del Corsano, Giuseppe; Masters, Ellen Kg; Habtewold, Tibebu; Christophides, George K.; Windbichler, Nikolai

Plasmodium oocysts respond with dormancy to crowding and nutritional stress

SCIENTIFIC REPORTS

IF3.9

2021-02-04

OAAI

Habtewold, Tibebu; Sharma, Aayushi A.; Wyer, Claudia A. S.; Masters, Ellen K. G.; Windbichler, Nikolai; Christophides, George K.

Antibiotic Treatment in Anopheles coluzzii Affects Carbon and Nitrogen Metabolism 按蚊的抗生素治疗会影响碳和氮代谢

PATHOGENS

IF3.3

2020-08-21

OAAI

Chabanol, Estelle; Behrends, Volker; Prevot, Ghislaine; Christophides, George K.; Gendrin, Mathilde

Stability of the effect of silencing fibronectin type III domain-protein 1 (FN3D1) gene on Anopheles arabiensis reared under different breeding site conditions

PARASITES & VECTORS

IF3.5

2020-04-19

OAAI

Debalke, Serkadis; Habtewold, Tibebu; Christophides, George K.; Duchateau, Luc

An epigenetic map of malaria parasite development from host to vector

SCIENTIFIC REPORTS

IF3.9

2020-04-14

OAAI

Witmer, Kathrin; Fraschka, Sabine A.; Vlachou, Dina; Bartfai, Richard; Christophides, George K.

PIMMS43 is required for malaria parasite immune evasion and sporogonic development in the mosquito vector PIMMS43是疟原虫免疫逃避和蚊媒孢子发育所必需的

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-03-12

OAAI

Ukegbu, Chiamaka V.; Giorgalli, Maria; Tapanelli, Sofia; Rona, Luisa D. P.; Jaye, Amie; Wyer, Claudia; Angrisano, Fiona; Blagborough, Andrew M.; Christophides, George K.; Vlachou, Dina

研究方向