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Discontinuous EBOV RNA synthesis events in patients with Ebola virus disease and their relationship to viral load and outcome of infection 埃博拉病毒病患者的间断性EBOV RNA合成事件及其与病毒载量和感染结局的关系 Dong, Xiaofeng; Garcia-Dorival, Isabel; Rickett, Natasha Y.; Bosworth, Andrew; Smither, Sophie; Dowall, Stuart; Carroll, Miles W.; Matthews, David A.; Laws, Thomas R.; Digard, Paul; Hiscox, Julian A. 分享 收藏
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A Novel Toolkit of SARS-CoV-2 Sub-Genomic Replicons for Efficient Antiviral Screening SARS-CoV-2亚基因组复制子的新型工具包,用于高效抗病毒筛选 Erdmann, Maximilian; Wing, Peter A. C.; Webb, Isobel; Kavanagh Williamson, Maia; Jearanaiwitayakul, Tuksin; Sullivan, Edward; Bazire, James; Shytaj, Iart Luca; Mckeating, Jane A.; Matthews, David A.; Davidson, Andrew D. 分享 收藏
Using minor variant genomes and machine learning to study the genome biology of SARS-CoV-2 over time 利用微小变异基因组与机器学习研究SARS-CoV-2随时间的基因组生物学 Dong, Xiaofeng; Matthews, David A.; Gallo, Giulia; Donovan-Banfield, I'ah; Goldswain, Hannah; Macgill, Tracy; Myers, Todd; Orr, Robert; Bailey, Dalan; Carroll, Miles W.; Hiscox, Julian A. 分享 收藏
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Current landscape of drug approvals for genitourinary (GU) cancers in North America and Europe 当前北美和欧洲泌尿生殖系统(GU)癌症药物审批的现状 Tapia, J. C.; Gavira, J.; Matthews, D.; Santoni, M.; Young, M. N.; Blondel, L.; Flippot, R.; Frazer, R.; Anguera, G.; Rey, J. P. Maroto 分享 收藏
Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19 Clark, Jordan J.; Penrice-Randal, Rebekah; Sharma, Parul; Dong, Xiaofeng; Pennington, Shaun H.; Marriott, Amy E.; Colombo, Stefano; Davidson, Andrew; Kavanagh Williamson, Maia; Matthews, David A.; Turtle, Lance; Prince, Tessa; Hughes, Grant L.; Patterson, Edward I.; Shawli, Ghada; Mega, Daniele F.; Subramaniam, Krishanthi; Sharp, Jo; Turner, Joseph D.; Biagini, Giancarlo A.; Owen, Andrew; Kipar, Anja; Hiscox, Julian A.; Stewart, James P. 分享 收藏
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Voluntary risk mitigation behaviour can reduce impact of SARS-CoV-2: a real-time modelling study of the January 2022 Omicron wave in England Brooks-Pollock, Ellen; Northstone, Kate; Pellis, Lorenzo; Scarabel, Francesca; Thomas, Amy; Nixon, Emily; Matthews, David A.; Bowyer, Vicky; Garcia, Maria Paz; Steves, Claire J.; Timpson, Nicholas J.; Danon, Leon 分享 收藏
Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication Yaron, Tomer M.; Heaton, Brook E.; Levy, Tyler M.; Johnson, Jared L.; Jordan, Tristan X.; Cohen, Benjamin M.; Kerelsky, Alexander; Lin, Ting-Yu; Liberatore, Katarina M.; Bulaon, Danielle K.; Nest, Samantha J. Van; Koundouros, Nikos; Kastenhuber, Edward R.; Mercadante, Marisa N.; Shobana-Ganesh, Kripa; He, Long; Schwartz, Robert E.; Chen, Shuibing; Weinstein, Harel; Elemento, Olivier; Piskounova, Elena; Nilsson-Payant, Benjamin E.; Lee, Gina; Trimarco, Joseph D.; Burke, Kaitlyn N.; Hamele, Cait E.; Chaparian, Ryan R.; Harding, Alfred T.; Tata, Aleksandra; Zhu, Xinyu; Tata, Purushothama Rao; Smith, Clare M.; Possemato, Anthony P.; Tkachev, Sasha L.; V. Hornbeck, Peter; Beausoleil, Sean A.; Anand, Shankara K.; Aguet, Francois; Getz, Gad; Davidson, Andrew D.; Heesom, Kate; Kavanagh-Williamson, Maia; Matthews, David A.; tenOever, Benjamin R.; Cantley, Lewis C.; Blenis, John; Heaton, Nicholas S. 分享 收藏
Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers 使用LeTRS分析细胞培养,动物模型和临床样品中SARS-CoV-2已知和新的亚基因组mrna,这是一种用于识别独特序列标识符的生物信息学工具 Dong, Xiaofeng; Penrice-Randal, Rebekah; Goldswain, Hannah; Prince, Tessa; Randle, Nadine; Donovan-Banfield, I'ah; Salguero, Francisco J.; Tree, Julia; Vamos, Ecaterina; Nelson, Charlotte; Clark, Jordan; Ryan, Yan; Stewart, James P.; Semple, Malcolm G.; Baillie, J. Kenneth; Openshaw, Peter J. M.; Turtle, Lance; Matthews, David A.; Carroll, Miles W.; Darby, Alistair C.; Hiscox, Julian A. 分享 收藏
Nanopore ReCappable sequencing maps SARS-CoV-2 5′ capping sites and provides new insights into the structure of sgRNAs 纳米孔可重新检测测序图SARS-CoV-2 5' 加帽位点,并为sgrna的结构提供了新的见解 Ugolini, Camilla; Mulroney, Logan; Leger, Adrien; Castelli, Matteo; Criscuolo, Elena; Williamson, Maia Kavanagh; Davidson, Andrew D.; Almuqrin, Abdulaziz; Giambruno, Roberto; Jain, Miten; Frige, Gianmaria; Olsen, Hugh; Tzertzinis, George; Schildkraut, Ira; Wulf, Madalee G.; Correa, Ivan R.; Ettwiller, Laurence; Clementi, Nicola; Clementi, Massimo; Mancini, Nicasio; Birney, Ewan; Akeson, Mark; Nicassio, Francesco; Matthews, David A.; Leonardi, Tommaso 分享 收藏
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2 Gupta, Kapil; Toelzer, Christine; Williamson, Maia Kavanagh; Shoemark, Deborah K.; Oliveira, A. Sofia F.; Matthews, David A.; Almuqrin, Abdulaziz; Staufer, Oskar; Yadav, Sathish K. N.; Borucu, Ufuk; Garzoni, Frederic; Fitzgerald, Daniel; Spatz, Joachim; Mulholland, Adrian J.; Davidson, Andrew D.; Schaffitzel, Christiane; Berger, Imre 分享 收藏
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction Khan, Hataf; Winstone, Helena; Jimenez-Guardeno, Jose M.; Graham, Carl; Doores, Katie J.; Goujon, Caroline; Matthews, David A.; Davidson, Andrew D.; Rihn, Suzannah J.; Palmarini, Massimo; Neil, Stuart J. D.; Malim, Michael H. 分享 收藏
Amplicon and Metagenomic Analysis of Middle East Respiratory Syndrome (MERS) Coronavirus and the Microbiome in Patients with Severe MERS 重度MERS患者中东呼吸综合征冠状病毒和微生物组的扩增子和宏基因组分析 Aljabr, Waleed; Alruwaili, Muhannad; Penrice-Randal, Rebekah; Alrezaihi, Abdulrahman; Harrison, Abbie Jasmine; Ryan, Yan; Bentley, Eleanor; Jones, Benjamin; Alhatlani, Bader Y.; AlShahrani, Dayel; Mahmood, Zana; Rickett, Natasha Y.; Alosaimi, Bandar; Naeem, Asif; Alamri, Saad; Alsran, Hadel; Hamed, Maaweya E.; Dong, Xiaofeng; Assiri, Abdullah M.; Alrasheed, Abdullah R.; Hamza, Muaawia; Carroll, Miles W.; Gemmell, Matthew; Darby, Alistair; Donovan-Banfield, I'ah; Stewart, James P.; Matthews, David A.; Davidson, Andrew D.; Hiscox, Julian A. 分享 收藏
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Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care Bosworth, Andrew; Rickett, Natasha Y.; Dong, Xiaofeng; Ng, Lisa F. P.; Garcia-Dorival, Isabel; Matthews, David A.; Fletcher, Tom; Jacobs, Michael; Thomson, Emma C.; Carroll, Miles W.; Hiscox, Julian A. 分享 收藏
Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism 基于扩增子的新型冠状病毒肺炎患者鼻咽拭子SARS-CoV-2检测和测序,并鉴定病毒基因组中编码干扰素拮抗蛋白的缺失 Moore, Shona C.; Penrice-Randal, Rebekah; Alruwaili, Muhannad; Randle, Nadine; Armstrong, Stuart; Hartley, Catherine; Haldenby, Sam; Dong, Xiaofeng; Alrezaihi, Abdulrahman; Almsaud, Mai; Bentley, Eleanor; Clark, Jordan; Garcia-Dorival, Isabel; Gilmore, Paul; Han, Ximeng; Jones, Benjamin; Luu, Lisa; Sharma, Parul; Shawli, Ghada; Sun, Yani; Zhao, Qin; Pullan, Steven T.; Carter, Daniel P.; Bewley, Kevin; Dunning, Jake; Zhou, En-min; Solomon, Tom; Beadsworth, Michael; Cruise, James; Crook, Derrick W.; Matthews, David A.; Davidson, Andrew D.; Mahmood, Zana; Aljabr, Waleed; Druce, Julian; Vipond, Richard; Ng, Lisa; Renia, Laurent; Openshaw, Peter J. M.; Baillie, J. Kenneth; Carroll, Miles W.; Stewart, James; Darby, Alistair; Semple, Malcolm; Turtle, Lance; Hiscox, Julian A. 分享 收藏