Thomas A. Edwards - Publications, H-index & Citations

Thomas A. Edwards

Larkin University

35H指数

206论文数

4.1K被引数

收录论文 51

发表时间

De novo grafted coiled-coil peptides as p53/hDM2 inhibitors 从头移植的螺旋-螺旋肽作为p53/hDM2抑制剂

rsc chem. biol.

IF0

2026-06-12

OAAI

Freya Spain; Diana Gimenez; Amanda M. Acevedo-Jake; Bram Mylemans; Nikolas J. Brooks; Boguslawa Korona; Danny T. Huang; Thomas A. Edwards; Aneika C. Leney; Laura Itzhaki; Derek N. Woolfson; Andrew J. Wilson

Accessing terapascal pressures on two-stage light-gas guns for high-energy-density research 通过两级轻气炮实现太帕斯卡级压力的高能量密度研究

Journal of Applied Physics

IF2.5

2026-01-14

PREAI

Gorman, M. G.; Burdiak, G. C.; Niasse, N.; Beltran, V.; Doherty, R. L.; Allison, J. R.; Allan, P.; Barker, R. L.; Betney, M.; Bordas, R.; Chapman, D. A.; Doyle, H. W.; Edwards, T.; Escauriza, E.; Guiga, R.; Hawker, N.; Joiner, N.; Kosteletos, T.; Parker, J.; Pecover, J. D.; Pesic, Z.; Read, J. S.; Read, M. P.; Ringrose, T.; Skidmore, J. W.; Ao, T.; Porwitzky, A.; Farfan, B.; Johnson, C.; Hansen, A.; Dolan, D.

Held out wings RNA binding activity in the cytoplasm during early spermatogenesis 在早期精子发生过程中，held out wings蛋白的RNA结合活性存在于细胞质中。

Communications Biology

IF5.1

2026-01-12

OAAI

Michaela Agapiou; Karl Norris; Tayah Hopes; Eilidh Ward; Fruzsina Hobor; Amanda Bretman; Thomas A. Edwards; Julie L. Aspden

The cryoEM structure of the Hendra henipavirus nucleoprotein reveals insights into paramyxoviral nucleocapsid architectures

SCIENTIFIC REPORTS

IF3.9

2024-06-18

OAAI

Passchier, Tim C.; White, Joshua B. R.; Maskell, Daniel P.; Byrne, Matthew J.; Ranson, Neil A.; Edwards, Thomas A.; Barr, John N.

Understanding β-strand mediated protein-protein interactions: tuning binding behaviour of intrinsically disordered sequences by backbone modification

CHEMICAL SCIENCE

IF7.4

2024-01-01

OAAI

Cawood, Emma E.; Baker, Emily; Edwards, Thomas A.; Woolfson, Derek N.; Karamanos, Theodoros K.; Wilson, Andrew J.

The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture

MBIO

IF4.7

2022-08-30

OAAI

Hopkins, Francis R.; Alvarez-Rodriguez, Beatriz; Heath, George R.; Panayi, Kyriakoulla; Hover, Samantha; Edwards, Thomas A.; Barr, John N.; Fontana, Juan

Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci

NUCLEIC ACIDS RESEARCH

IF13.1

2022-02-07

OAAI

Mohamad, Merianne; Nicholson, David; Saha, Chayan Kumar; Hauryliuk, Vasili; Edwards, Thomas A.; Atkinson, Gemma C.; Ranson, Neil A.; O'Neill, Alex J.

Understanding p300-transcription factor interactions using sequence variation and hybridization

RSC CHEMICAL BIOLOGY

IF3.1

2022-01-01

OAAI

Hobor, Fruzsina; Hegedus, Zsofia; Ibarra, Amaurys Avila; Petrovicz, Vencel L.; Bartlett, Gail J.; Sessions, Richard B.; Wilson, Andrew J.; Edwards, Thomas A.

RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site

NATURE COMMUNICATIONS

IF15.7

2021-06-30

OAAI

Haza, Katarzyna Z.; Martin, Heather L.; Rao, Ajinkya; Turner, Amy L.; Saunders, Sophie E.; Petersen, Britta; Tiede, Christian; Tipping, Kevin; Tang, Anna A.; Ajayi, Modupe; Taylor, Thomas; Harvey, Maia; Fishwick, Keri M.; Adams, Thomas L.; Gaule, Thembaninkosi G.; Trinh, Chi H.; Johnson, Matthew; Breeze, Alexander L.; Edwards, Thomas A.; McPherson, Michael J.; Tomlinson, Darren C.

Identification of β-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation

CHEMICAL SCIENCE

IF7.4

2021-01-01

OAAI

Hegedus, Zsofia; Hobor, Fruzsina; Shoemark, Deborah K.; Celis, Sergio; Lian, Lu-Yun; Trinh, Chi H.; Sessions, Richard B.; Edwards, Thomas A.; Wilson, Andrew J.

Query-guided protein-protein interaction inhibitor discovery

CHEMICAL SCIENCE

IF7.4

2021-01-01

OAAI

Celis, Sergio; Hobor, Fruzsina; James, Thomas; Bartlett, Gail J.; Ibarra, Amaurys A.; Shoemark, Deborah K.; Hegedus, Zsofia; Hetherington, Kristina; Woolfson, Derek N.; Sessions, Richard B.; Edwards, Thomas A.; Andrews, David M.; Nelson, Adam; Wilson, Andrew J.

Towards optimizing peptide-based inhibitors of protein-protein interactions: predictive saturation variation scanning (PreSaVS)

RSC CHEMICAL BIOLOGY

IF3.1

2021-01-01

OAAI

Hetherington, Kristina; Dutt, Som; Ibarra, Amaurys A.; Cawood, Emma E.; Hobor, Fruzsina; Woolfson, Derek N.; Edwards, Thomas A.; Nelson, Adam; Sessions, Richard B.; Wilson, Andrew J.

Development of a multiplex assay for antibody detection in serum against pathogens affecting ruminants

TRANSBOUNDARY AND EMERGING DISEASES

IF3

2020-08-29

OAAI

Hoste, Alexis C. R.; Ruiz, Tamara; Fernandez-Pacheco, Paloma; Angel Jimenez-Clavero, Miguel; Djadjovski, Igor; Moreno, Sandra; Brun, Alejandro; Edwards, Thomas A.; Barr, John N.; Rueda, Paloma; Sastre, Patricia

Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric diagnostic tests

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2020-06-03

OAAI

Alvarez-Rodriguez, Beatriz; Tiede, Christian; Hoste, Alexis C. R.; Surtees, Rebecca A.; Trinh, Chi; Slack, Gillian S.; Chamberlain, John; Hewson, Roger; Fresco, Alba; Sastre, Patricia; Tomlinson, Darren C.; Millner, Paul A.; Edwards, Thomas A.; Barr, John N.

Stapled Peptides as HIF-1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2020-05-26

OAAI

Hetherington, Kristina; Hegedus, Zsofia; Edwards, Thomas A.; Sessions, Richard B.; Nelson, Adam; Wilson, Andrew J.

A missense variant in specificity protein 6 (SP6) is associated with amelogenesis imperfecta

HUMAN MOLECULAR GENETICS

IF3.2

2020-03-13

OAAI

Smith, Claire E. L.; Whitehouse, Laura L. E.; Poulter, James A.; Wilkinson Hewitt, Laura; Nadat, Fatima; Jackson, Brian R.; Manfield, Iain W.; Edwards, Thomas A.; Rodd, Helen D.; Inglehearn, Chris F.; Mighell, Alan J.

Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces

ACS CHEMICAL BIOLOGY

IF3.8

2019-09-27

OAAI

Ibarra, Amaurys A.; Bartlett, Gail J.; Hegedus, Zsofia; Dutt, Som; Hobor, Fruzsina; Horner, Katherine A.; Hetherington, Kristina; Spence, Kirstin; Nelson, Adam; Edwards, Thomas A.; Woolfson, Derek N.; Sessions, Richard B.; Wilson, Andrew J.

Tula orthohantavirus nucleocapsid protein is cleaved in infected cells and may sequester activated caspase-3 during persistent infection to suppress apoptosis

JOURNAL OF GENERAL VIROLOGY

IF4.3

2019-08-01

OAAI

Davies, Katherine; Afrough, Babak; Mankouri, Jamet; Hewson, Roger; Edwards, Thomas A.; Barr, John N.

Reply to Rameix-Welti, No Incongruity in Respiratory Syncytial Virus M2-1 Protein Remaining Bound to Viral mRNAs during Their Entire Life Time

MBIO

IF4.7

2019-06-25

OAAI

Edwards, Thomas A.; Barr, John N.

Hazara nairovirus elicits differential induction of apoptosis and nucleocapsid protein cleavage in mammalian and tick cells

JOURNAL OF GENERAL VIROLOGY

IF4.3

2019-03-01

OAAI

Fuller, J.; Surtees, R. A.; Shaw, A. B.; Alvarez-Rodriguez, B.; Slack, G. S.; Bell-Sakyi, Lesley; Mankouri, J.; Edwards, T. A.; Hewson, R.; Barr, J. N.

研究方向