Karine G. Le Roch - Publications, H-index & Citations

Karine G. Le Roch

University of California

49H指数

224论文数

8.6K被引数

收录论文 71

发表时间

A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis 不同的疟原虫NEK4是驱动减数分裂早期事件的关键调节剂

Nature Communications

IF15.7

2026-05-12

OAAI

Ryuji Yanase; Molly Hair; Mohammad Zeeshan; David J. P. Ferguson; Declan Brady; Carla Pasquarello; Andrew Bottrill; Suhani Bhanvadia; Armund Neal; Eelco C. Tromer; Karine G. Le Roch; Alexandre Hainard; Anthony A. Holder; Sue Vaughan; David S. Guttery; Rita Tewari

Host-cell dependent epigenetic profiles associated with survival outcomes in T. gondii infection 宿主细胞依赖的表观遗传谱与弓形虫感染生存结局的关联

Epigenetics & Chromatin

IF3.5

2026-05-05

OAAI

Loic Ciampossin; Arzu Ulu; Todd Lenz; Zehao Li; Steven Abel; Sandeep Srivastava; Michael White; Emma Wilson; Karine G. Le Roch

Babesia hegotelforum sp. nov., a zoonotic Babesia species previously referred to as Babesia sp. MO1 巴贝斯虫新种Babesia hegotelforum sp. nov.，一种先前被称为Babesia sp. MO1的人畜共患巴贝斯虫。

Emerging Microbes and Infections

IF7.5

2026-03-06

OAAI

Pallavi Singh; Karel Estrada; Luis Miguel Gonzalez; Ricardo Grande; Sergio Sánchez-Prieto; Emmanuel Cornillot; Omar Harb; Alejandro Sanchez-Flores; Estrella Montero; Karine G. Le Roch; Stefano Lonardi; Choukri Ben Mamoun

Plasmodium ARK1 regulates spindle formation during atypical mitosis and forms a divergent chromosomal passenger complex 疟原虫ARK1调控非典型有丝分裂过程中的纺锤体形成，并形成一种分化的染色体乘客复合物。

Nature Communications

IF15.7

2026-02-26

OAAI

Annu Nagar; Ryuji Yanase; Mohammad Zeeshan; David J. P. Ferguson; Steven Abel; Sarah L. Pashley; Akancha Mishra; Anthonius Eze; Edward Rea; Declan Brady; Andrew R. Bottrill; Sue Vaughan; Karine G. Le Roch; David S. Guttery; Anthony A. Holder; Eelco C. Tromer; Pushkar Sharma; Rita Tewari

ASPred: identification of antigen apecific B-cell receptors from single V(D)J sequences using large language models ASPred: 使用大型语言模型从单个V(D)J序列中鉴定抗原特异性b细胞受体

JOURNAL OF IMMUNOLOGY

IF3.4

2025-11-01

PREAI

Paco, Karen; Mendivil, Mariana Paco; Zhang, Zihao; Roman, Isabel Condori; Zebardast, Sanaz; Olatoyinbo, Peace O.; Alam, Rashid M.; Davila Ojeda, Christian; Patel, Dhruv; Felix, Jonathan; Yang, Tristan; Bin Ashraf, Faisal; Lay, Jordan; Tolstorukov, Ilya; Le Roch, Karine; Sazinsky, Matthew H.; Hernandez, Jeniffer; Lonardi, Stefano; Barroso da Silva, Fernando L.; Ray, Animesh

A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites 药物重定位方法揭示了恶性疟原虫休眠子中可靶向的表观遗传通路

ELIFE

IF0

2025-09-30

PREAI

Maher, Steven P.; Bakowski, Malina A.; Vantaux, Amelie; Flannery, Erika L.; Andolina, Chiara; Gupta, Mohit; Antonova-Koch, Yevgeniya; Argomaniz, Magdalena; Cabrera-Mora, Monica; Campo, Brice; Chao, Alexander T.; Chatterjee, Arnab K.; Cheng, Wayne T.; Chuenchob, Vorada; Cooper, Caitlin A.; Cottier, Karissa; Galinski, Mary R.; Harupa-Chung, Anke; Ji, Hana; Joseph, Sean B.; Lenz, Todd; Lonardi, Stefano; Matheson, Jessica; Mikolajczak, Sebastian A.; Moeller, Timothy; Orban, Agnes; Padin-Irizarry, Vivian; Pan, Kastin; Peneau, Julie; Prudhomme, Jacques; Roesch, Camille; Ruberto, Anthony; Sabnis, Saniya S.; Saney, Celia L.; Sattabongkot, Jetsumon; Sereshki, Saleh; Suriyakan, Sangrawee; Ubalee, Ratawan; Wang, Yinsheng; Wasisakun, Praphan; Yin, Jiekai; Popovici, Jean; McNamara, Case W.; Joyner, Chester; Nosten, Francois H.; Witkowski, Benoit; Le Roch, Karine G.; Kyle, Dennis E.

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-10-16

OAAI

Barnes, Griffin L.; Magann, Nicholas L.; Perrotta, Daniele; Hormann, Fabian M.; Fernandez, Sebastian; Vydyam, Pratap; Choi, Jae-Yeon; Prudhomme, Jacques; Neal, Armund; Le Roch, Karine G.; Ben Mamoun, Choukri; Vanderwal, Christopher D.

The Toxoplasma gondii F-Box Protein L2 Functions as a Repressor of Stage Specific Gene Expression

PLOS PATHOGENS

IF4.9

2024-05-30

OAAI

Baptista, Carlos G.; Hosking, Sarah; Gas-Pascual, Elisabet; Ciampossine, Loic; Abel, Steven; Hakimi, Mohamed-Ali; Jeffers, Victoria; Le Roch, Karine; West, Christopher M.; Blader, Ira J.

Proteome-Wide Identification of RNA-dependent proteins and an emerging role for RNAs in Plasmodium falciparum protein complexes

NATURE COMMUNICATIONS

IF15.7

2024-02-14

OAAI

Hollin, Thomas; Abel, Steven; Banks, Charles; Hristov, Borislav; Prudhomme, Jacques; Hales, Kianna; Florens, Laurence; Stafford Noble, William; Le Roch, Karine G.

An ex vivo model of Toxoplasma recrudescence reveals developmental plasticity of the bradyzoite stage

MBIO

IF4.7

2023-10-31

OAAI

Vizcarra, Edward A.; Goerner, Amber L.; Ulu, Arzu; Hong, David D.; Bergersen, Kristina V.; Talavera, Michael A.; Le Roch, Karine; Wilson, Emma H.; White, Michael W.

Epigenetic Regulation and Chromatin Remodeling in Malaria Parasites

ANNUAL REVIEW OF MICROBIOLOGY

IF9.9

2023-09-15

OAAI

Hollin, Thomas; Chahine, Zeinab; Le Roch, Karine G.

Plasmodium ARK2 and EB1 drive unconventional spindle dynamics, during chromosome segregation in sexual transmission stages

NATURE COMMUNICATIONS

IF15.7

2023-09-13

OAAI

Zeeshan, Mohammad; Rea, Edward; Abel, Steven; Vukusic, Kruno; Markus, Robert; Brady, Declan; Eze, Antonius; Rashpa, Ravish; Balestra, Aurelia C.; Bottrill, Andrew R.; Brochet, Mathieu; Guttery, David S.; Tolic, Iva M.; Holder, Anthony A.; Le Roch, Karine G.; Tromer, Eelco C.; Tewari, Rita

Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum

NATURE COMMUNICATIONS

IF15.7

2023-08-22

OAAI

Batugedara, Gayani; Lu, Xueqing M.; Hristov, Borislav; Abel, Steven; Chahine, Zeinab; Hollin, Thomas; Williams, Desiree; Wang, Tina; Cort, Anthony; Lenz, Todd; Thompson, Trevor A.; Prudhomme, Jacques; Tripathi, Abhai K.; Xu, Guoyue; Cudini, Juliana; Dogga, Sunil; Lawniczak, Mara; Noble, William Stafford; Sinnis, Photini; Le Roch, Karine G.

The role of long noncoding RNAs in malaria parasites

Trends in Parasitology

IF6.6

2023-07-01

OAAI

Thompson, Trevor A.; Chahine, Zeinab; Le Roch, Karine G.

Small RNA sequencing of field Culex mosquitoes identifies patterns of viral infection and the mosquito immune response

SCIENTIFIC REPORTS

IF3.9

2023-06-30

OAAI

Abel, Steven M. M.; Hong, Zhenchen; Williams, Desiree; Ireri, Sally; Brown, Michelle Q. Q.; Su, Tianyun; Hung, Kim Y. Y.; Henke, Jennifer A. A.; Barton, John P. P.; Le Roch, Karine G. G.

An Enantiospecific Synthesis of Isoneoamphilectane Confirms Its Strained Tricyclic Structure

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-02-02

OAAI

Dwulet, Natalie C.; Chahine, Zeinab; Le Roch, Karine G.; Vanderwal, Christopher D.

Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum

NATURE COMMUNICATIONS

IF15.7

2022-03-11

OAAI

Hollin, Thomas; Abel, Steven; Falla, Alejandra; Pasaje, Charisse Flerida A.; Bhatia, Anil; Hur, Manhoi; Kirkwood, Jay S.; Saraf, Anita; Prudhomme, Jacques; De Souza, Amancio; Florens, Laurence; Niles, Jacquin C.; Le Roch, Karine G.

A newly characterized malaria antigen on erythrocyte and merozoite surfaces induces parasite inhibitory antibodies

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-08-03

OAAI

Michelow, Ian C.; Park, Sangshin; Tsai, Shu-Whei; Rayta, Bonnie; Pasaje, Charisse Flerida A.; Nelson, Sara; Early, Angela M.; Frosch, Anne P.; Ayodo, George; Raj, Dipak K.; Nixon, Christina E.; Nixon, Christian P.; Pond-Tor, Sunthorn; Friedman, Jennifer F.; Fried, Michal; Duffy, Patrick E.; Le Roch, Karine G.; Niles, Jacquin C.; Kurtis, Jonathan D.

Third-generation sequencing revises the molecular karyotype for Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants

GENOME RESEARCH

IF5.5

2021-04-27

OAAI

Xia, Jing; Venkat, Aarthi; Bainbridge, Rachel E.; Reese, Michael L.; Le Roch, Karine G.; Ay, Ferhat; Boyle, Jon P.

Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins apicomplexans或RAP蛋白中丰富的RNA结合域的鉴定和系统发育分析

MICROBIAL GENOMICS

IF4

2021-03-01

OAAI

Hollin, Thomas; Jaroszewski, Lukasz; Stajich, Jason E.; Godzik, Adam; Le Roch, Karine G.

研究方向