logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
N

Nicholas Chim

university of california irvine

22H指数
63论文数
1.6K被引数
收录论文 25
发表时间
logo
How custom polymerases are driving innovation in synthetic biology定制聚合酶如何推动合成生物学创新
errCurrent Opinion in Chemical Biology
IF6.1
err2026-04-15
err0
PREAI
errMohammad Hajjar; Alex R. Horton; Victoria A. Maola; Nicholas Chim; John C. Chaput
err分享
err收藏
Xeno-nucleic acids support formation of Ag(I)-mediated duplexes and silver nanoclusters外源核酸支持Ag(I)介导的双链体和银纳米簇的形成
errNucleic Acids Research
IF13.1
err2026-02-27
err0
PREAI
errGuha, Rweetuparna; Bethur, Eshana; Chim, Nicholas; Gupta, Manoj K.; Lin, I-Hsin; Taylor, Rebecca E.; Chaput, John C.; Copp, Stacy M.
err分享
err收藏
Rapid evolution of a highly efficient RNA polymerase by homologous recombination通过同源重组实现高效RNA聚合酶的快速进化
errNature Chemical Biology
IF13.7
err2026-01-07
err0
PREAI
errEsau L. Medina; Victoria A. Maola; Mohammad Hajjar; Grace K. Ko; Ethan J. Ho; Alexandria R. Horton; Nicholas Chim; John C. Chaput
err分享
err收藏
Directed evolution of a TNA polymerase identifies independent paths to fidelity and catalysisTNA聚合酶的定向进化确定了通向保真度和催化作用的独立路径
errNature Communications
IF15.7
err2025-12-19
err0
errOAAI
errMohammad Hajjar; Victoria A. Maola; Joy J. Lee; Manuel J. Holguin; Riley N. Quijano; Kalvin K. Nguyen; Katherine L. Ho; Jenny V. Medina; Elionel Botello-Cornejo; Bhawna Barpuzary; Nicholas Chim; John C. Chaput
err分享
err收藏
Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid
errNUCLEIC ACIDS RESEARCH
IF13.1
err2022-09-17
err4
errOAAI
errHajjar, Mohammad; Chim, Nicholas; Liu, Chao; Herdewijn, Piet; Chaput, John C.
err分享
err收藏
Evolution of Functionally Enhanced α-L-Threofuranosyl Nucleic Acid Aptamers功能增强的 α-l-三呋喃糖基核酸适体的进化
errACS SYNTHETIC BIOLOGY
IF3.9
err2021-11-05
err30
errOAAI
errMcCloskey, Cailen M.; Li, Qingfeng; Yik, Eric J.; Chim, Nicholas; Ngor, Arlene K.; Medina, Esau; Grubisic, Ivan; Keh, Lance Co Ting; Poplin, Ryan; Chaput, John C.
err分享
err收藏
Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2021-10-12
err28
PREAI
errLi, Qingfeng; Maola, Victoria A.; Chim, Nicholas; Hussain, Javeena; Lozoya-Colinas, Adriana; Chaput, John C.
err分享
err收藏
Transliteration of synthetic genetic enzymes
errNUCLEIC ACIDS RESEARCH
IF13.1
err2021-10-11
err0
errOAAI
errWang, Yajun; Liu, Xiaolin; Shehabat, Mouhamad; Chim, Nicholas; Chaput, John C.
err分享
err收藏
Following replicative DNA synthesis by time-resolved X-ray crystallography
errNATURE COMMUNICATIONS
IF15.7
err2021-05-11
err16
errOAAI
errChim, Nicholas; Meza, Roman A.; Trinh, Anh M.; Yang, Kefan; Chaput, John C.
err分享
err收藏
Engineering polymerases for applications in synthetic biology
errQUARTERLY REVIEWS OF BIOPHYSICS
IF5.3
err2020-07-27
err53
errOAAI
errNikoomanzar, Ali; Chim, Nicholas; Yik, Eric J.; Chaput, John C.
err分享
err收藏
Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase作为XNA逆转录酶的天然DNA聚合酶的晶体结构
errNUCLEIC ACIDS RESEARCH
IF13.1
err2019-06-06
err35
errOAAI
errJackson, Lynnette N.; Chim, Nicholas; Shi, Changhua; Chaput, John C.
err分享
err收藏
Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway
errELIFE
IF0
err2018-10-19
err18
errOAAI
errChim, Nicholas; Jackson, Lynnette N.; Trinh, Anh M.; Chaput, John C.
err分享
err收藏
Synthesis of 2′-Deoxy-α-L-threofuranosyl Nucleoside Triphosphates
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2018-07-16
err9
PREAI
errBala, Saikat; Liao, Jen-Yu; Zhang, Li; Tran, Chantel N.; Chim, Nicholas; Chaput, John C.
err分享
err收藏
Structural basis for TNA synthesis by an engineered TNA polymerase
errNATURE COMMUNICATIONS
IF15.7
err2017-11-27
err48
errOAAI
errChim, Nicholas; Shi, Changhua; Sau, Sujay P.; Nikoomanzar, Ali; Chaput, John C.
err分享
err收藏
Heme uptake in bacterial pathogens
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2014-04-01
err122
errOAAI
errContreras, Heidi; Chim, Nicholas; Credali, Alfredo; Goulding, Celia W.
err分享
err收藏
Insights into redox sensing metalloproteins in Mycobacterium tuberculosis
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2014-04-01
err25
errOAAI
errChim, Nicholas; Johnson, Parker M.; Goulding, Celia W.
err分享
err收藏
Structures of Oligomers of a Peptide from β-Amyloid (vol 135, pg 12460, 2013)
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2014-03-04
err0
errOAAI
errPham, Johnny D.; Chim, Nicholas; Goulding, Celia W.; Nowick, James S.
err分享
err收藏
Structures of Oligomers of a Peptide from β-Amyloid
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2013-08-08
err65
errOAAI
errPham, Johnny D.; Chim, Nicholas; Goulding, Celia W.; Nowick, James S.
err分享
err收藏
Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2013-08-07
err60
errOAAI
errOwens, Cedric P.; Chim, Nicholas; Goulding, Celia W.
err分享
err收藏
The Mycobacterium tuberculosis Secreted Protein Rv0203 Transfers Heme to Membrane Proteins MmpL3 and MmpL11
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-07-01
err96
errOAAI
errOwens, Cedric P.; Chim, Nicholas; Graves, Amanda B.; Harmston, Christine A.; Iniguez, Angelina; Contreras, Heidi; Liptak, Matthew D.; Goulding, Celia W.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
M
M.R. Sawaya
H 指数: 94 · 论文数: 631
M
Marcus A. Horwitz
H 指数: 77 · 论文数: 197
P
Piet Herdewijn
H 指数: 73 · 论文数: 1.2K
王亚军 封面图
王亚军 (Yajun Wang)
H 指数: 73 · 论文数: 603
J
Julian P. Whitelegge
H 指数: 72 · 论文数: 437
查看更多