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J

J.S. Brunzelle

northwestern university
H指数:43
被引数:7,642

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荣誉奖项

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TONSL/TONSOKU binding to histone H3.1 is required for DNA repair

TONSL/TONSOKU与组蛋白H3.1的结合对于DNA修复是必需的

Science Advances
IF12.5
2026-10-160
OA
Hossein Davarinejad; Cloé Laflamme; Bianca Dupont; Sydney Lunde-Ingrey; Marcelo Muñoz; Monika Joshi; Sabina Sarvan; Hailey R. Graham; Alex Ross; Joseph S. Brunzelle; Élise G. Lavoie; Emilio I. Alarcon; Joey G. Sheff; Amélie Fradet-Turcotte; Jean-François Couture
S-Adenosylhomocysteine Analogs Selectively Suppress Pan-Coronavirus Replication by Inhibition of nsp14 Methyltransferase

S-腺苷同型半胱氨酸类似物通过抑制nsp14甲基转移酶选择性抑制泛冠状病毒复制

ACS Medicinal Chemistry Letters
IF4
2025-11-050
PRE
Monica Rosas-Lemus; Sudhakar Athe; George Minasov; Jason A. Pattie; Joseph S. Brunzelle; Irene Chau; Fengling Li; Masoud Vedadi; Heng Ma; Arvind Ramanathan; Mark E. Becker; Thomas J. Hope; Hazem Abdelkarim; Patrick Grudzien; Vadim Gaponenko; Jeffrey E. Montgomery; Raymond E. Moellering; Viresh H. Rawal; Karla J. F. Satchell
Bench to Bedside Using the iSAFE Discovery and Development Platform for CNS Protein Kinase Inhibitors: A Phase 2 Clinical Asset Example

从实验室到临床应用：利用iSAFE发现和开发平台研发中枢神经系统蛋白激酶抑制剂——以一项II期临床项目为例

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
2025-03-010
PRE
Roy, Saktimayee M.; Shuvalova, Ludmilla; Minasov, George; Brunzelle, Joseph S.; Pelletier, Jeffrey C.; Arancio, Ottavio; Watterson, Daniel Martin
Torsional twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

SARS-CoV和SARS-CoV-2 SUD-N和SUD-M结构域的扭转扭曲

PROTEIN SCIENCE
IF5.2
2025-02-190
OAAI
Rosas-Lemus, Monica; Minasov, George; Brunzelle, Joseph S.; Taha, Taha Y.; Lemak, Sofia; Yin, Shaohui; Shuvalova, Ludmilla; Rosecrans, Julia; Khanna, Kanika; Seifert, H. Steven; Savchenko, Alexei; Stogios, Peter J.; Ott, Melanie; Satchell, Karla J. F.
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors
ACS INFECTIOUS DISEASES
IF3.8
2023-09-207
OA
Inniss, Nicole L.; Kozic, Jan; Li, Fengling; Rosas-Lemus, Monica; Minasov, George; Rybacek, Jiri; Zhu, Yingjie; Pohl, Radek; Shuvalova, Ludmilla; Rulisek, Lubomir; Brunzelle, Joseph S.; Bednarova, Lucie; Stefek, Milan; Kormanik, Jan Michael; Andris, Erik; Sebestik, Jaroslav; Li, Alice Shi Ming; Brown, Peter J.; Schmitz, Uli; Saikatendu, Kumar; Chang, Edcon; Nencka, Radim; Vedadi, Masoud; Satchell, Karla J. F.
Cytochrome c lysine acetylation regulates cellular respiration and cell death in ischemic skeletal muscle
NATURE COMMUNICATIONS
IF15.7
2023-07-137
OAAI
Morse, Paul T.; Perez-Mejias, Gonzalo; Wan, Junmei; Turner, Alice A.; Marquez, Inmaculada; Kalpage, Hasini A.; Vaishnav, Asmita; Zurek, Matthew P.; Huettemann, Philipp P.; Kim, Katherine; Arroum, Tasnim; de la Rosa, Miguel A.; Chowdhury, Dipanwita Dutta; Lee, Icksoo; Brunzelle, Joseph S.; Sanderson, Thomas H.; Malek, Moh H.; Meierhofer, David; Edwards, Brian F. P.; Diaz-Moreno, Irene; Huettemann, Maik
Structure of an AMPK complex in an inactive, ATP-bound state

处于无活性，ATP结合状态的AMPK复合物的结构

Science
IF45.8
2021-01-010
OA
Yan Yan; Somnath Mukherjee; Kaleeckal G. Harikumar; Timothy S. Strutzenberg; X. Edward Zhou; Kelly M. Suino-Powell; Ting-Hai Xu; Ryan D. Sheldon; Jared A. Lamp; J.S. Brunzelle; Katarzyna Radziwon; Abigail E. Ellis; Scott J. Novick; Irving E. Vega; Russell G. Jones; Laurence J. Miller; H. Eric Xu; Patrick R. Griffin; Anthony A. Kossiakoff; Karsten Melcher

研究方向

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G
G. Minasov
H 指数:38论文数:523被引数:5,112
J
Jean‐François Couture
H 指数:25论文数:47被引数:2,807
K
Karsten Melcher
H 指数:61论文数:214被引数:1.6万
H
H. Eric Xu
H 指数:100论文数:632被引数:4.0万
M
Mónica Rosas‐Lemus
H 指数:16论文数:57被引数:955
L
L. Shuvalova
H 指数:19论文数:336被引数:1,208
K
K.J.F. Satchell
H 指数:44论文数:301被引数:5,329
W
W.F. Anderson
H 指数:59论文数:817被引数:1.2万
X
X. Edward Zhou
H 指数:45论文数:140被引数:1.0万
S
Sabina Sarvan
H 指数:9论文数:35被引数:367