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M

Michal Hocek

Czech Academy of Sciences

54H指数
612论文数
1.0W被引数
收录论文 156
发表时间
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Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases2,6-二取代和2,6,9-三取代7-脱氮嘌呤碱基的合成与生物活性
errChemMedChem
IF3.4
err2026-09-07
err0
errOAAI
errUgnė Šinkevičiūtė; Kateřina Burgetová Ječmeňová; Soňa Gurská; Lenka Poštová Slavětínská; Vincent Baran; Pavel Polishchuk; Petr Džubák; Michal Hocek; Marián Hajdúch; Michal Tichý
err分享
err收藏
Biotin- and Chloroalkane-Modified Nucleotides for Dual Display of Proteins on DNA Through Streptavidin and Halotag Binding生物素-和氯代烷烃修饰的核苷酸通过链霉亲和素和Halotag结合实现蛋白质的双展示
errAngewandte Chemie-International Edition
IF16.9
err2026-08-28
err0
errOAAI
errGiammarco Liuni; Lenka Poštová Slavětínská; Miroslav Hájek; Veronika Raindlová; Michal Hocek
err分享
err收藏
Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries从过表达的含双核苷碱基修饰的DNA文库中快速单轮筛选靶向胰岛素受体的超修饰适配体
errNature Communications
IF15.7
err2026-05-27
err0
errOAAI
errPablo Alberto Franco-Urquijo; Marek Ondruš; Jaroslav Kurfürst; Jana Škerlová; Irena Selicharová; Lucie Mužíková Čechová; Hana Šváchová; Alena Semerádtová; Anatolij Filimoněnko; Adéla Fejfarová; Jiří Homola; Tomáš Kouba; Michal Hocek
err分享
err收藏
Hydrophobic alkyl-linked base-modified pyrimidine and 7-deazapurine 2′-deoxyribonucleoside phosphoramidites: synthesis and application in solid-phase synthesis of modified and hypermodified oligonucleotides疏水烷基连接的碱基修饰嘧啶和7-脱氮嘌呤2′-脱氧核糖核苷磷酰胺酯：合成及其在固相合成修饰和超修饰寡核苷酸中的应用
errRSC Adv.
IF0
err2025-12-09
err0
errOAAI
errIvana Jestřábová; Lucie Bednárová; Lenka Poštová Slavětínská; Michal Hocek
err分享
err收藏
Potent Competitive Inhibitors of Ecto-5′-nucleotidase (CD73) based on 6-(Het)aryl-7-deazapurine Ribonucleoside 5′-O-Bisphosphonates
errACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
IF3.7
err2025-12-01
err0
PREAI
errSinkeviciute, Ugne; Simova, Magdalena; Stanik, Radek; Postova Slavetinska, Lenka; Blazkova, Kristyna; Sacha, Pavel; Lepsik, Martin; Rezac, Jan; Konvalinka, Jan; Ormsby, Tereza; Tichy, Michal; Hocek, Michal
err分享
err收藏
Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability; Translation; and CRISPR-Cas9 Cleavage酶促合成含5-甲基-或5-乙基嘧啶或取代7-脱氮嘌呤的修饰RNA及其修饰对稳定性、翻译和CRISPR-Cas9切割的影响
errACS Chemical Biology
IF3.8
err2025-11-05
err0
errOAAI
errTania Sanchez-Quirante; Erika Kužmová; Miguel Riopedre-Fernandez; Sebastian Golojuch; Pavel Vopálenský; Veronika Raindlová; Afaf H. El-Sagheer; Tom Brown; Michal Hocek
err分享
err收藏
Super-Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation超分辨率兼容的DNA标记技术揭示分化过程中染色质的移动性和组织结构变化
errAdvanced Science
IF14.1
err2025-09-09
err0
errOAAI
errMaruthi K. Pabba; Miroslav Kuba; Tomáš Kraus; Kerem Celikay; Janis Meyer; Sunil Kumar Pradhan; Andreas Maiser; Hartmann Harz; Heinrich Leonhardt; Karl Rohr; Michal Hocek; M. Cristina Cardoso
err分享
err收藏
Versatile Enzymatic Approach for Truncation, Labeling, and Mutation of Nucleobase-Modified Aptamers Demonstrated on Indole-Modified β-Conglutin Aptamer
errCHEMBIOCHEM
IF2.8
err2025-09-01
err1
errOAAI
errOndrus, Marek; Franco-Urquijo, Pablo Alberto; Lerga, Teresa Mairal; Muzikova Cechova, Lucie; Bermudo Redondo, M. Carmen; O'Sullivan, Ciara K.; Hocek, Michal
err分享
err收藏
Identification of 6-Aryl-7-Deazapurine Ribonucleoside Phosphonates as Inhibitors of Ecto-5′-Nucleotidase (CD73)鉴定6-芳基-7-脱氮嘌呤核糖核苷磷酸酯作为外源性5'-核苷酸酶(CD73)的抑制剂
errACS Pharmacology & Translational Science
IF3.7
err2025-07-17
err0
errOAAI
errMagdalena Šímová; Tereza Ormsby; Ugnė Šinkevičiu̅tė; Lucia Sirotová Veselovská; Kateřina Čermáková; Martin Hadzima; Lenka Bartoň; Jana Staňurová; Anežka Kramná; Pavel Šácha; Michal Tichý; Michal Hocek; Jan Konvalinka; Kristyna Blazkova
err分享
err收藏
Synthesis of 2-Substituted Adenosine Triphosphate Derivatives and their use in Enzymatic Synthesis and Postsynthetic Labelling of RNA2-取代腺苷三磷酸衍生物的合成及其在酶促RNA合成和合成后标记中的应用
errCHEMBIOCHEM
IF2.8
err2025-05-21
err0
PREAI
errSinkeviciute, Ugne; Sanchez-Quirante, Tania; Rozankova, Samanta; Slavetinska, Lenka Postova; Raindlova, Veronika; Hocek, Michal
err分享
err收藏
Enzymatic synthesis of reactive RNA probes containing squaramate-linked cytidine or adenosine for bioconjugations and cross-linking with lysine-containing peptides and proteins酶促合成含有方酸连接的胞苷或腺苷的反应性RNA探针，用于与含赖氨酸的肽和蛋白质进行生物缀合和交联
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2025-01-02
err0
errOAAI
errIvancova, Ivana; Quirante, Tania Sanchez; Ondrus, Marek; Pohl, Radek; Vlkova, Marta; Zilecka, Eva; Boura, Evzen; Hocek, Michal
err分享
err收藏
Using environment-sensitive tetramethylated thiophene-BODIPY fluorophores in DNA probes for studying effector-induced conformational changes of protein-DNA complexes
errRSC CHEMICAL BIOLOGY
IF3.1
err2025-01-01
err0
errOAAI
errSoltysova, Marketa; Guixens-Gallardo, Pedro; Sieglova, Irena; Soldanova, Anna; Krejcirikova, Veronika; Fabry, Milan; Brynda, Jiri; Khoroshyy, Petro; Hocek, Michal; Rezacova, Pavlina
err分享
err收藏
Bacteriophage-related epigenetic natural and non-natural pyrimidine nucleotides and their influence on transcription with T7 RNA polymerase
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2024-11-09
err2
errOAAI
errGracias, Filip; Pohl, Radek; Sykorova, Veronika; Hocek, Michal
err分享
err收藏
Glyco-DNA: Enzymatic Synthesis of Base-Modified and Hypermodified DNA Displaying up to Four Different Monosaccharide Units in the Major Groove
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2024-08-02
err3
errOAAI
errKromer, Matous; Slavetinska, Lenka Postova; Hocek, Michal
err分享
err收藏
Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases (vol 15, 3054, 2023)
errNATURE COMMUNICATIONS
IF15.7
err2024-05-17
err0
errOAAI
errBrunderova, Maria; Havlicek, Vojtech; Matyasovsky, Jan; Pohl, Radek; Postova Slavetinska, Lenka; Kromer, Matous; Hocek, Michal
err分享
err收藏
Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides
errACS OMEGA
IF4.3
err2024-04-27
err0
errOAAI
errFleuti, Marianne; Sanchez-Quirante, Tania; Postova Slavetinska, Lenka; Tloustova, Eva; Tichy, Michal; Gurska, Sona; Dzubak, Petr; Hajduch, Marian; Hocek, Michal
err分享
err收藏
Expedient production of site specifically nucleobase-labelled or hypermodified RNA with engineered thermophilic DNA polymerases
errNATURE COMMUNICATIONS
IF15.7
err2024-04-09
err5
errOAAI
errBrunderova, Maria; Havlicek, Vojtech; Matyasovsky, Jan; Pohl, Radek; Postova Slavetinska, Lenka; Kromer, Matous; Hocek, Michal
err分享
err收藏
Superanionic DNA: enzymatic synthesis of hypermodified DNA bearing four different anionic substituents at all four nucleobases
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-10-23
err6
errOAAI
errKuprikova, Natalia; Ondrus, Marek; Bednarova, Lucie; Riopedre-Fernandez, Miguel; Slavetinska, Lenka Postova; Sykorova, Veronika; Hocek, Michal
err分享
err收藏
Arylethynyl- or Alkynyl-Linked Pyrimidine and 7-Deazapurine 2′-Deoxyribonucleoside 3′-Phosphoramidites for Chemical Synthesis of Hypermodified Hydrophobic Oligonucleotides芳乙炔基或炔基连接的嘧啶和7-脱氮嘌呤2'-脱氧核糖核苷3'-亚磷酰胺用于超修饰的疏水性寡核苷酸的化学合成
errACS OMEGA
IF4.3
err2023-10-12
err1
errOAAI
errJestrabova, Ivana; Slavetinska, Lenka Postova; Hocek, Michal
err分享
err收藏
Normalized Multipotential Redox Coding of DNA Bases for Determination of Total Nucleotide Composition
errANALYTICAL CHEMISTRY
IF6.7
err2023-08-14
err2
errOAAI
errKodr, David; Ortiz, Mayreli; Sykorova, Veronika; Yenice, Cansu Pinar; Lesnikowski, Zbigniew J.; O'Sullivan, Ciara K.; Hocek, Michal
err分享
err收藏

研究方向

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