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乐世敏 封面图

乐世敏 (Shimin Le)

Xiamen University

24H指数
74论文数
1.8K被引数
收录论文 43
发表时间
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Harmonizing Competing Intermediates: A Unified Free Energy Landscape of Protein RNase H
errChinese Physics Letters
IF4.2
err2026-02-01
err0
PREAI
errPing Yu; Zhenyong Xue; Hao Sun; Zhiqi Hou; Zhuwei Zhang; Yang Wang; Shimin Le; Hu Chen
err分享
err收藏
Salt-bridge mediated cooperativity and mechanical stabilization of tandem spectrin repeats盐桥介导的协同性和串联血影蛋白串联重复序列的机械稳定性
errNanoscale Horiz.
IF6.6
err2025-07-21
err0
PREAI
errYanzhong Wang ‡; Yuhang Zhang ‡; Miao Yu; Peng Xiu; Yanwei Jia; Hu Chen; Shimin Le; Jin Qian; Jie Yan
err分享
err收藏
Mechanically weak and highly dynamic state of mechanosensitive titin Ig domains induced by proline isomerization由脯氨酸异构化诱导的机械敏感性肌联蛋白Ig结构域的力学弱和高度动态状态
errNATURE COMMUNICATIONS
IF15.7
err2025-03-20
err0
errOAAI
errWang, Yukai; Ye, Jiaqing; Liu, Xian; Zhang, Zhuwei; Shang, Fei; Qi, Xingyu; Zhang, Yuhang; Du, Jingyi; Sun, Hao; Xu, Jiashu; Chen, Hu; Yu, Miao; Le, Shimin
err分享
err收藏
Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-09-05
err0
errOAAI
errLe, Shimin; Yu, Miao; Fu, Chaoyu; Heier, Jonathon A.; Martin, Sterling; Hardin, Jeff; Yan, Jie
err分享
err收藏
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification
errNATURE COMMUNICATIONS
IF15.7
err2024-07-21
err0
errOAAI
errZhang, Yuhang; Du, Jingyi; Liu, Xian; Shang, Fei; Deng, Yunxin; Ye, Jiaqing; Wang, Yukai; Yan, Jie; Chen, Hu; Yu, Miao; Le, Shimin
err分享
err收藏
Structural domain in the Titin N2B-us region binds to FHL2 in a force-activation dependent manner
errNATURE COMMUNICATIONS
IF15.7
err2024-05-27
err2
errOAAI
errSun, Yuze; Liu, Xuyao; Huang, Wenmao; Le, Shimin; Yan, Jie
err分享
err收藏
Comparative analysis of folding and unfolding dynamics and free-energy landscapes in homologous cold shock proteins with variable thermal stabilities
errPHYSICAL REVIEW RESEARCH
IF4.2
err2024-05-14
err2
errOAAI
errXue, Zhenyong; Sun, Hao; Hong, Haiyan; Zhang, Zhuwei; Zhang, Yuhang; Guo, Zilong; Le, Shimin; Chen, Hu
err分享
err收藏
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein
errAPL BIOENGINEERING
IF4.1
err2024-03-01
err0
errOAAI
errHuang, Wenmao; Liu, Jingzhun; Le, Shimin; Yao, Mingxi; Shi, Yi; Yan, Jie
err分享
err收藏
Mechanical Stabilization of a Bacterial Adhesion Complex
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-09-07
err12
errOAAI
errHuang, Wenmao; Le, Shimin; Sun, Yuze; Lin, Dennis Jingxiong; Yao, Mingxi; Shi, Yi; Yan, Jie
err分享
err收藏
Force-Dependent Interactions between Talin and Full-Length Vinculin
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2021-08-31
err40
errOAAI
errWang, Yinan; Yao, Mingxi; Baker, Karen B.; Gough, Rosemarie E.; Le, Shimin; Goult, Benjamin T.; Yan, Jie
err分享
err收藏
Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-07-01
err34
errOAAI
errGough, Rosemarie E.; Jones, Matthew C.; Zacharchenko, Thomas; Le, Shimin; Yu, Miao; Jacquemet, Guillaume; Muench, Ste P.; Yan, Jie; Humphries, Jonathan D.; Jorgensen, Claus; Humphries, Martin J.; Goult, Benjamin T.
err分享
err收藏
Mechanical instability of adherens junctions overrides intrinsic quiescence of hair follicle stem cells
errDEVELOPMENTAL CELL
IF8.7
err2021-03-01
err13
errOAAI
errBiswas, Ritusree; Banerjee, Avinanda; Lembo, Sergio; Zhao, Zhihai; Lakshmanan, Vairavan; Lim, Ryan; Le, Shimin; Nakasaki, Manando; Kutyavin, Vassily; Wright, Graham; Palakodeti, Dasaradhi; Ross, Robert S.; Jamora, Colin; Vasioukhin, Valeri; Jie, Yan; Raghavan, Srikala
err分享
err收藏
Mechanical regulation of tension-transmission supramolecular linkages
errCURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE
IF13.4
err2021-02-01
err7
PREAI
errLe, Shimin; Yu, Miao; Yan, Jie
err分享
err收藏
Fungal Wound Healing through Instantaneous Protoplasmic Gelation
errCURRENT BIOLOGY
IF7.5
err2021-01-01
err7
errOAAI
errTu Anh Nguyen; Le, Shimin; Lee, Michelle; Fan, Jing-Song; Yang, Daiwen; Yan, Jie; Jedd, Gregory
err分享
err收藏
Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains
errNATURE COMMUNICATIONS
IF15.7
err2020-09-08
err13
errOAAI
errYu, Miao; Zhao, Zhihai; Chen, Zibo; Le, Shimin; Yan, Jie
err分享
err收藏
Mechanical regulation of formin-dependent actin polymerizationformin依赖性肌动蛋白聚合的机械调节
errSEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
IF6
err2020-06-01
err22
PREAI
errLe, Shimin; Yu, Miao; Bershadsky, Alexander; Yan, Jie
err分享
err收藏
Implementing Optogenetic Modulation in Mechanotransduction
errPHYSICAL REVIEW X
IF15.7
err2020-04-01
err14
errOAAI
errYu, Miao; Le, Shimin; Barnett, Samuel; Guo, Zhenhuan; Zhong, Xueying; Kanchanawong, Palcorn; Yan, Jie
err分享
err收藏
Direct single-molecule quantification reveals unexpectedly high mechanical stability of vinculin-talin/α-catenin linkages
errSCIENCE ADVANCES
IF12.5
err2019-12-06
err42
errOAAI
errLe, Shimin; Yu, Miao; Yan, Jie
err分享
err收藏
Single-molecule manipulation quantification of site-specific DNA binding
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2019-12-01
err13
PREAI
errZhao, Xiaodan; Guo, Shiwen; Lu, Chen; Chen, Jin; Le, Shimin; Fu, Hongxia; Yan, Jie
err分享
err收藏
Label-free Single-Molecule Quantification of Rapamycin-induced FKBP-FRB Dimerization for Direct Control of Cellular Mechanotransduction
errNANO LETTERS
IF9.1
err2019-08-30
err23
errOAAI
errWang, Yinan; Barnett, Samuel F. H.; Le, Shimin; Guo, Zhenhuan; Zhong, Xueying; Kanchanawong, Pakorn; Yan, Jie
err分享
err收藏

研究方向

单分子与单细胞生物物理、软凝聚态物理、生物医用材料等
合作学者
合作期刊
M
Michael P. Sheetz
H 指数: 127 · 论文数: 512
C
Chwee Teck Lim
H 指数: 123 · 论文数: 766
M
Martin J. Humphries
H 指数: 101 · 论文数: 614
A
Anna Akhmanova
H 指数: 90 · 论文数: 534
W
Walter Chazin
H 指数: 85 · 论文数: 471
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