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Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD+-bound protomer chains Brucella ovis来源的短链脱氢酶的晶体结构,包含apo形式和结合NAD+辅酶的原聚体链 Zupko, Sean P.; Konstanty, Amelia T.; Mayclin, Steve J.; Choi, Ryan; Serbzhinskiy, Dmitry; Robles, Emily; Moses, Victoria; Barrett, Lynn K.; Van Voorhis, Wesley C.; Edwards, Tom E.; Myler, Peter J.; Torelli, Andrew T.; French, Jarrod B.; Hicks, Katherine A. 分享 收藏
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Architecture of Pseudomonas aeruginosa glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases 铜绿假单胞菌谷氨酰-tRNA合成酶的结构定义了一类二聚体Ib型氨酰-tRNA合成酶的亚家族。 Fenwick, Michael K.; Mayclin, Stephen J.; Seibold, Steve; DeRocher, Amy E.; Subramanian, Sandhya; Phan, Isabelle Q.; Dranow, David M.; Lorimer, Donald D.; Abramov, Ariel B.; Choi, Ryan; Hewitt, Stephen Nakazawa; Edwards, Thomas E.; Bullard, James M.; Battaile, Kevin P.; Wower, Iwona K.; Soe, Aimee C.; Tsutakawa, Susan E.; Lovell, Scott; Myler, Peter J.; Wower, Jacek; Staker, Bart L. 分享 收藏
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens Fenwick, Michael K.; Pierce, Phillip G.; Abendroth, Jan; Barrett, Kayleigh F.; Barrett, Lynn K.; Bowatte, Kalinga; Choi, Ryan; Chun, Ian; Conrady, Deborah G.; Craig, Justin K.; Dranow, David M.; Hammerson, Bradley; Higgins, Tate; Lorimer, Donald D.; Lukat, Peer; Mayclin, Stephen J.; Hewitt, Stephen Nakazawa; Peng, Ying Po; Shanbhogue, Ashwini; Smutney, Hayden; Stigliano, Matthew Z. Z.; Tillery, Logan M.; Udell, Hannah S.; Wallace, Ellen G.; Derocher, Amy E.; Phan, Isabelle Q.; Staker, Bart L.; Subramanian, Sandhya; Van Voorhis, Wesley C.; Blankenfeldt, Wulf; Mueller, Rolf; Edwards, Thomas E.; Myler, Peter J. 分享 收藏
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A divergent protein kinase A regulatory subunit essential for morphogenesis of the human pathogen Leishmania Weinberger, Renana Fischer; Bachmaier, Sabine; Ober, Veronica; Githure, George B.; Dandugudumula, Ramu; Phan, Isabelle Q.; Almoznino, Michal; Polatoglou, Eleni; Tsigankov, Polina; Koren, Roni Nitzan; Myler, Peter J.; Boshart, Michael; Zilberstein, Dan 分享 收藏
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Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases Kassu, Mintesinot; Parvatkar, Prakash T.; Milanes, Jillian; Monaghan, Neil P.; Kim, Chungsik; Dowgiallo, Matthew; Zhao, Yingzhao; Asakawa, Ami H.; Huang, Lili; Wagner, Alicia; Miller, Brandon; Carter, Karissa; Barrett, Kayleigh F.; Tillery, Logan M.; Barrett, Lynn K.; Phan, Isabelle Q.; Subramanian, Sandhya; Myler, Peter J.; Van Voorhis, Wesley C.; Leahy, James W.; Rice, Christopher A.; Kyle, Dennis E.; Morris, James; Manetsch, Roman 分享 收藏
Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development Fenwick, Michael K.; Reers, Alexandra R.; Liu, Yi; Zigweid, Rachael; Sankaran, Banumathi; Shin, Janis; Hulverson, Matthew A.; Hammerson, Bradley; Alvaro, Elena Fernandez; Myler, Peter J.; Kaushansky, Alexis; Van Voorhis, Wesley C.; Fan, Erkang; Staker, Bart L. 分享 收藏
Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts Rodriguez-Hernandez, Diego; Vijayan, Kamalakannan; Zigweid, Rachael; Fenwick, Michael K.; Sankaran, Banumathi; Roobsoong, Wanlapa; Sattabongkot, Jetsumon; Glennon, Elizabeth K. K.; Myler, Peter J.; Sunnerhagen, Per; Staker, Bart L.; Kaushansky, Alexis; Grotli, Morten 分享 收藏
Immunization with a Trypanosoma cruzi cyclophilin-19 deletion mutant protects against acute Chagas disease in mice Jha, Bijay Kumar; Varikuti, Sanjay; Verma, Chaitenya; Shivahare, Rahul; Bishop, Nicholas; Dos Santos, Gregory P.; McDonald, Jacquelyn; Sur, Aakash; Myler, Peter J.; Schenkman, Sergio; Satoskar, Abhay R.; McGwire, Bradford S. 分享 收藏
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Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody Xie, Bin; Maker, Allison; Priest, Andrew, V; Dranow, David M.; Phan, Jenny N.; Edwards, Thomas E.; Staker, Bart L.; Myler, Peter J.; Gumbiner, Barry M.; Sivasankar, Sanjeevi 分享 收藏
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