Mikhail Kashlev - Publications, H-index & Citations

Mikhail Kashlev

national cancer institute

50H指数

134论文数

8.9K被引数

收录论文 58

发表时间

Chromatin buffers torsional stress during transcription 染色质缓冲转录过程中的扭转应力

Science

IF45.8

2025-12-18

PREAI

Jin Qian; Lucyna Lubkowska; Shuming Zhang; Chuang Tan; Yifeng Hong; Xiaomeng Jia; Robert M. Fulbright; James T. Inman; Taryn M. Kay; Joshua Jeong; Glenn Hauk; Deanna Gotte; James M. Berger; Mikhail Kashlev; Michelle D. Wang

Nascent RNA profiling reveals genome-wide productive reiterative initiation regulating gene transcription in bacteria 新生RNA分析揭示了细菌中调控基因转录的基因组范围有效重复起始。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-12-11

PREAI

Sun, Zhe; Huang, Guozhong; Zhang, Yuqiong; Wang, Shuang; Kashlev, Mikhail

Robust regulation of transcription pausing in Escherichia coli by the ubiquitous elongation factor NusG

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-06-05

OAAI

V. Yakhnin, Alexander; Bubunenko, Mikhail; Mandell, Zachary F.; Lubkowska, Lucyna; Flusher, Sara; Babitzke, Paul; Kashlev, Mikhail

The fidelity of transcription in human cells 人类细胞转录的保真度

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-01-25

OAAI

Chung, Claire; Verheijen, Bert M.; Zhang, Xinmin; Huang, Biao; Coakley, Aeowynn; McGann, Eric; Wade, Emily; Dinep-Schneider, Olivia; LaGosh, Jessica; Anagnostou, Maria-Eleni; Simpson, Stephen; Thomas, Kelly; Ernst, Mimi; Rattray, Allison; Lynch, Michael; Kashlev, Mikhail; Benayoun, Berenice A.; Li, Zhongwei; Strathern, Jeffrey; Gout, Jean-Francois; Vermulst, Marc

NusG is an intrinsic transcription termination factor that stimulates motility and coordinates gene expression with NusA

ELIFE

IF0

2021-04-09

OAAI

Mandell, Zachary F.; Oshiro, Reid T.; Yakhnin, Alexander, V; Vishwakarma, Rishi; Kashlev, Mikhail; Kearns, Daniel B.; Babitzke, Paul

Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria

NATURE COMMUNICATIONS

IF15.7

2021-02-10

OAAI

Sun, Zhe; Yakhnin, Alexander, V; FitzGerald, Peter C.; McIntosh, Carl E.; Kashlev, Mikhail

NusG-dependent RNA polymerase pausing is a frequent function of this universally conserved transcription elongation factor NusG依赖性RNA聚合酶暂停是这种普遍保守的转录延伸因子的常见功能

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

IF6.4

2020-10-02

OAAI

Yakhnin, Alexander V.; Kashlev, Mikhail; Babitzke, Paul

NusG controls transcription pausing and RNA polymerase translocation throughout the Bacillus subtilis genome

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-08-17

OAAI

Yakhnin, Alexander V.; FitzGerald, Peter C.; McIntosh, Carl; Yakhnin, Helen; Kireeva, Maria; Turek-Herman, Joshua; Mandell, Zachary F.; Kashlev, Mikhail; Babitzke, Paul

NusG-Dependent RNA Polymerase Pausing and TylosinDependent Ribosome Stalling Are Required for Tylosin Resistance by Inducing 23S rRNA Methylation in Bacillus subtilis

MBIO

IF4.7

2019-12-24

OAAI

Yakhnin, Helen; Yakhnin, Alexander V.; Mouery, Brandon L.; Mandell, Zachary F.; Karbasiafshar, Catherine; Kashlev, Mikhail; Babitzke, Paul

RNA-DNA and DNA-DNA base-pairing at the upstream edge of the transcription bubble regulate translocation of RNA polymerase and transcription rate

NUCLEIC ACIDS RESEARCH

IF13.1

2018-05-16

OAAI

Klreeva, Maria; Trang, Cyndi; Matevosyan, Gayane; Turek-Herman, Joshua; Chasov, Vitaly; Lubkowska, Lucyna; Kashlev, Mikhail

Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II RNA聚合酶II转录停滞和绕过碱性DNA损伤的结构基础

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-02-27

OAAI

Wang, Wei; Walmacq, Celine; Chong, Jenny; Kashlev, Mikhail; Wang, Dong

A Cre Transcription Fidelity Reporter Identifies GreA as a Major RNA Proofreading Factor in Escherichia coli

GENETICS

IF5.1

2017-05-01

OAAI

Bubunenko, Mikhail G.; Court, Carolyn B.; Rattray, Alison J.; Gotte, Deanna R.; Kireeva, Maria L.; Irizarry-Caro, Jorge A.; Li, Xintian; Jin, Ding J.; Court, Donald L.; Strathern, Jeffrey N.; Kashlev, Mikhail

T7 replisome directly overcomes DNA damage

NATURE COMMUNICATIONS

IF15.7

2015-12-17

OAAI

Sun, Bo; Pandey, Manjula; Inman, James T.; Yang, Yi; Kashlev, Mikhail; Patel, Smita S.; Wang, Michelle D.

Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo (vol 16, 98, 2015)

GENOME BIOLOGY

IF9.4

2015-12-02

OAAI

Imashimizu, Masahiko; Takahashi, Hiroki; Oshima, Taku; McIntosh, Carl; Bubunenko, Mikhail; Court, Donald L.; Kashlev, Mikhail

Allosteric Activation of Bacterial Swi2/Snf2 (Switch/Sucrose Non-fermentable) Protein RapA by RNA Polymerase BIOCHEMICAL AND STRUCTURAL STUDIES

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-09-01

OAAI

Kakar, Smita; Fang, Xianyang; Lubkowska, Lucyna; Zhou, Yan Ning; Shaw, Gary X.; Wang, Yun-Xing; Jin, Ding Jun; Kashlev, Mikhail; Ji, Xinhua

Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo

GENOME BIOLOGY

IF9.4

2015-05-15

OAAI

Imashimizu, Masahiko; Takahashi, Hiroki; Oshima, Taku; McIntosh, Carl; Bubunenko, Mikhail; Court, Donald L.; Kashlev, Mikhail

Productive mRNA stem loop-mediated transcriptional slippage: Crucial features in common with intrinsic terminators

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-04-06

OAAI

Penno, Christophe; Sharma, Virag; Coakley, Arthur; Motherway, Mary O'Connell; van Sinderen, Douwe; Lubkowska, Lucyna; Kireeva, Maria L.; Kashlev, Mikhail; Baranov, Pavel V.; Atkins, John F.

Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions 氧化环嘌呤DNA损伤的RNA聚合酶II旁路机制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-01-20

OAAI

Walmacq, Celine; Wang, Lanfeng; Chong, Jenny; Scibelli, Kathleen; Lubkowska, Lucyna; Gnatt, Averell; Brooks, Philip J.; Wang, Dong; Kashlev, Mikhail

A Genetic Assay for Transcription Errors Reveals Multilayer Control of RNA Polymerase II Fidelity

PLOS GENETICS

IF3.7

2014-09-18

OAAI

Irvin, Jordan D.; Kireeva, Maria L.; Gotte, Deanna R.; Shafer, Brenda K.; Huang, Ingold; Kashlev, Mikhail; Strathern, Jeffrey N.