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C

Christian Klein

ludwig-maximilians-universität münchen

76H指数
1.1K论文数
2.8W被引数
收录论文 262
发表时间
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Author Correction: The evolving role of cytokines for CAR-T cell manufacturing and beyond作者更正：细胞因子在CAR-T细胞制备及其后续应用中的演变作用
errNature Biomedical Engineering
IF26.6
err2026-08-10
err0
PREAI
errMar Guaza-Lasheras; Johanna Nimmerfroh; Dominic Schwarz; Tanja D. de Gruijl; Jessica Hartmann; Christian Klein; Heinz Läubli; Michal Lotem; Joerg Mittelstaet; Christophe Paget; Sine Reker Hadrup; Sonja Schallenberg; Per Thor Straten; Sebastian Theurich; Dario Venetz; Alfred Zippelius; Laurence Zitvogel; Sebastian Kobold
err分享
err收藏
The evolving role of cytokines for CAR-T cell manufacturing and beyond细胞因子在CAR-T细胞制备及其应用中的演变角色
errNature Biomedical Engineering
IF26.6
err2026-06-29
err0
PREAI
errMar Guaza-Lasheras; Johanna Nimmerfroh; Dominic Schwarz; Tanja D. de Grujil; Jessica Hartmann; Christian Klein; Heinz Läubli; Michal Lotem; Joerg Mittelstaet; Christophe Paget; Sine Reker Hadrup; Sonja Schallenberg; Per Thor Straten; Sebastian Theurich; Dario Venetz; Alfred Zippelius; Laurence Zitvogel; Sebastian Kobold
err分享
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Impact of ASO conjugation and receptor binding affinity on intracellular transport of mono- and bispecific TfR- and CD98-BrainshuttleTM variants
errmAbs
IF7.3
err2026-06-22
err0
errOAAI
errTatjana Sela; Tamara Wirth; Annika Sommer; Vincent Larraillet; Joachim Butzer; Sabine Lohmann; Pia Wittmann; Christian Klein; Hendrik Knoetgen; Roberto Villasenor; Annette Indlekofer; Kerstin Hofer; Felix Schumacher; Jens Niewöhner
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Distinct Extracellular Matrix Protein Signatures of Cortical and Cancellous Bone Allografts Following Processing for Clinical Use皮质骨和松质骨异体移植物在临床应用处理后的不同细胞外基质蛋白特征
errCells
IF5.2
err2026-05-04
err0
errOAAI
errAdrian Lendvai; Hans Peter Weitzenböck; Christian Klein; Christoph Wiesner; Rita Seeboeck; Barbara Entler; Benjamin Neuditschko; Franz Herzog; Michael Matzner; Monika Pichler; Andrea De Luna; Stefan Nehrer; Harald Hundsberger
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Cleaving through complexity: Pan-serotype fluorimetric assays for the dengue virus proteases通过复杂性切割：登革病毒蛋白酶的泛血清型荧光测定法
errSLAS Discovery
IF2.7
err2026-04-28
err0
errOAAI
errMiguel M. Macedo; Johannes Lang; Katharina Eckstein; Selina L. Muffler; Leah M. Glanzmann; Christian Klein; Mila-M. Leuthold
err分享
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Engineering of acidic pH-responsive anti-CD3 binding antibodies酸性pH响应性抗CD3结合抗体的工程化
errmAbs
IF7.3
err2026-04-27
err0
errOAAI
errGrégory La Sala; Katharina B. Kroell; Mudita Pincha; Christian Gassner; Lorenzo Deho; Ekkehard Moessner; Xavier Gueripel; Nicole Borin; Moritz Classen; Jörg Benz; Alexander Bujotzek; Christian Klein; Guy Georges; Adrian Hugenmatter; Klaus R. Liedl; Anna Vangone
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CEA-4-1BBL: CEACAM5-Targeted 4-1BB Ligand Fusion Proteins for Cis Co-Stimulation with CEA-TCBCEA-4-1BBL: 靶向CEACAM5的4-1BB配体融合蛋白，用于与CEA-TCB的顺式协同刺激
errAntibodies
IF2.7
err2026-03-03
err0
errOAAI
errChristina Claus; Claudia Ferrara-Koller; Johannes Sam; Sabine Lang; Rosmarie Albrecht; Regula B. Buser; Esther Bommer; Grégory La Sala; Valeria G. Nicolini; Sara Colombetti; Marina Bacac; Pablo Umaña; Christian Klein
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P329G-engager: a universal mix & match antibody-based adaptor platform for cancer immunotherapy
errMABS
IF7.3
err2026-01-22
err0
PREAI
errSurowka, Marlena; Darowski, Diana; Hutter-Karakoc, Idil; Claus, Christina; Ferrara-Koller, Claudia; Freimoser-Grundschober, Anne; Hofer, Thomas; Sam, Johannes; Gianotti, Reto; Sobieniecki, Andrzej; Assisi, Denis; Challier, John; Leclair, Stephane; Mossner, Ekkehard; Amann, Maria; Umana, Pablo; Klein, Christian
err分享
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De novo sequencing of glycans by ion mobility-mass spectrometry using a self-expanding database利用离子迁移-质谱法进行糖苷键从头测序并使用自扩展数据库
errNature Communications
IF15.7
err2025-12-13
err0
errOAAI
errJavier Sastre Toraño; Julia C. C. Vreugdenhil; Gaël M. Vos; Kevin C. Hooijschuur; Shannon Vogelaar; Christian Klein; John Fjeldsted; Bernd Stahl; Geert-Jan Boons
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Advanced cytokine-based immunotherapies: targeted cis-delivery strategies for enhanced anti-tumor efficacy and reduced toxicity高级细胞因子为基础的免疫疗法：靶向顺式递送策略以提高抗肿瘤疗效并降低毒性
errmAbs
IF7.3
err2025-11-14
err0
errOAAI
errLaurène Pousse; Amrita Manchala; Christian Klein; Laura Codarri Deak
err分享
err收藏
Optimizing efficacy and safety of T cell bispecific antibodies: the interdependence of CD3 and tumor antigen binder affinities in FOLR1 and CEACAM5 2 + 1 TCBs优化T细胞双特异性抗体的疗效与安全性：FOLR1和CEACAM5 2 + 1 TCBs中CD3和肿瘤抗原结合物亲和力的相互依赖性
errmAbs
IF7.3
err2025-11-06
err0
errOAAI
errOmar Abdelmotaleb; Anneliese Schneider; Inja Waldhauer; Johannes Sam; Thomas Hofer; Martin Lechmann; Anne Freimoser-Grundschober; Anna Maria Giusti; Katharina Essig; Tijana Nikic; Linda Steinacher; Christian Gassner; Stephan Märsch; Ali Bransi; Alex Odermatt; Peter Brünker; Sara Colombetti; Christian Klein
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Reinvigorating exhausted T cells in glioblastoma via PD1-IL2v immunocytokine therapy通过PD1-IL2v免疫细胞因子疗法重振胶质母细胞瘤中的耗竭T细胞
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errSalazar, Ulisse; Taskoparan, Betul; Deplazes, Sereina; Nicolini, Valeria; Codarri-Deak, Laura; Okada, Hideho; Klein, Christian; vom Berg, Johannes
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A REINVIGORATING EXHAUSTED T CELLS IN GLIOBLASTOMA VIA PD1-IL2V IMMUNOCYTOKINE THERAPY通过PD1-IL2V免疫细胞因子疗法重新激活胶质母细胞瘤中的耗竭T细胞
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSalazar, U.; Taskoparan, B.; Codarri Deak, L.; Nicolini, V; Klein, C.; Okada, H.; vom Berg, J.
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Dynamic alterations of dural and bone marrow B cells in an animal model of progressive multiple sclerosis进行性多发性硬化动物模型中硬脑膜和骨髓B细胞的动态变化
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2025-09-18
err0
PREAI
errFlorescu, Alexandra; Zuo, Michelle; Wang, Angela A.; Champagne-Jorgensen, Kevin; Noor, Mohammed A.; Ward, Lesley A.; van Puijenbroek, Erwin; Klein, Christian; Gommerman, Jennifer L.
err分享
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PD-1–targeted cis-delivery of an IL-2 variant induces a multifaceted antitumoral T cell response in human lung cancerPD-1靶向的同向递送IL-2变体在人类肺癌中诱导了多方面的抗肿瘤T细胞反应
errScience Translational Medicine
IF14.6
err2025-09-17
err0
PREAI
errIrene Fusi; Clara Serger; Petra Herzig; Markus Germann; Michael T. Sandholzer1; Nicole Oelgarth1; Petra C. Schwalie; Leyla Don; Viola K. Vetter; Viktor H. Koelzer; Didier Lardinois; Henry Kao; Laura Codarri Deak; Pablo Umaña; Christian Klein; Aljaz Hojski; Marina Natoli; Alfred Zippelius
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Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies黑色素瘤中的慢性抗原刺激诱导T细胞耗竭并限制T细胞双特异性疗法的疗效
errOncoImmunology
IF6.3
err2025-08-26
err0
errOAAI
errIdil Hutter-Karakoc; Eleni Maria Varypataki; Aparna Neelakandhan; Simone Lang; Vesna Kramar; Ahmet Varol; Sasha Simons; Marine Richard; Mudita Pincha; Dario Venetz; Johannes Sam; Nicole Joller; Christian Münz; Pablo Umana; Christian Klein; Maria Amann
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Targeting mutated KRAS by HLA-A*02:01 restricted anti-KRAS TCR-mimic CAR and bispecific T cell engager靶向突变型KRAS的HLA-A*02:01限制性抗-KRAS TCR模拟CAR及双特异性T细胞衔接剂
errJournal of Molecular Medicine
IF0
err2025-08-12
err0
errOAAI
errSaber Ebrahimi; Benedikt J. Lohnes; Shamsul A. Khan; Matthias Peipp; Ernesto Bockamp; Christian Klein; Hinrich Abken; Catherine Wölfel; Matthias Theobald; Udo F. Hartwig
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Preclinical advances in glofitamab combinations: a new frontier for Non-Hodgkin Lymphomaglofitamab组合的预临床进展：非霍奇金淋巴瘤的新前沿
errBlood
IF23.1
err2025-08-05
err0
errOAAI
errJohannes Sam; Gabrielle Leclercq-Cohen; Samuel Gebhardt; Marlena Surowka; Sylvia Herter; Katharina Lechner; James Relf; Stefanie Briner; Ahmet Varol; Birte Appelt; Ioana Domocos; Valeria Nicolini; Miriam Bez; Esther Bommer; Silvia Jenni; Anne Schoenle; Marine Le Clech; Sara Colombetti; Christian Klein; Pablo Umaña; Pontus Lundberg; Koorosh Korfi; Alessia Bottos; Marina Bacac
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Resolving the structural basis of therapeutic antibody function in cancer immunotherapy with RESI利用RESI解析癌症免疫治疗中治疗性抗体功能的结构基础
errNature Communications
IF15.7
err2025-07-23
err0
errOAAI
errIsabelle Pachmayr; Luciano A. Masullo; Susanne C. M. Reinhardt; Jisoo Kwon; Maite Llop; Ondřej Skořepa; Sylvia Herter; Marina Bacac; Christian Klein; Ralf Jungmann
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Single-Chain Fab Chain-Exchange (scFab-PACE) converts targeted prodrugs into functional T cell engagers on tumor cells单链Fab链交换(scFab-PACE)将靶向前药转化为肿瘤细胞上的功能性T细胞结合剂
errJournal of Biological Chemistry
IF3.9
err2025-07-16
err0
errOAAI
errVedran Vasic; Steffen Dickopf; Klaus Mayer; Johanna Gebhard; Michaela Fischer; Mohamed Anany; Can Buldun; Ellis Durner; Sinem Oeztuerk; Christian Klein; Ulrich Brinkmann
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err收藏

研究方向

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合作学者
合作期刊
I
Ian A. Wilson
H 指数: 179 · 论文数: 1.7K
M
Michael P. Manns
H 指数: 163 · 论文数: 2.1K
J
Josep Tabernero
H 指数: 146 · 论文数: 2.7K
J
John A. Todd
H 指数: 142 · 论文数: 1.1K
G
Gilles Salles
H 指数: 129 · 论文数: 1.7K
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