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Nikhil Gadewal

tata memorial centre

H指数:13

被引数:662

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Hotspot mutations in HER2 interfaces destabilize structure, causing breast cancer treatment failure

HER2界面上的热点突变会破坏结构稳定性，导致乳腺癌治疗失败。

IF7.3

2025-12-150

OAAI

The deubiquitinase inhibitor WP1130 drives nuclear aggregation and reactivation of mutant p53 for selective cancer cell targeting

IF4.2

2025-03-010

OAAI

Loss of correlated proteasomal subunit expression selectively promotes the 20SHigh state which underlies luminal breast tumorigenicity

COMMUNICATIONS BIOLOGY

IF5.1

2025-01-150

OAAI

In silico screening of phytochemicals against chromatin modifier, SETD7 for remodeling of the immunosuppressive tumor microenvironment in renal cancer

MOLECULAR DIVERSITY

IF3.8

2024-11-270

OAAI

High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer

IF7.7

2024-03-011

OAAI

Mechanistic influence of discreet conformation of human telomerase linker region

人端粒酶连接区域离散构象的机制性影响

biomolecular structure dynamics

IF0

2024-02-060

PRE

Pathogenic HER3 dimerization domain mutations create a structural bias towards un-conventional EGFR-HER3 signalling axis in breast cancer

致病性HER3二聚化结构域突变在乳腺癌中产生了对非常规EGFR-HER3信号轴的结构偏向

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2023-07-013

PRE

6-Shogaol Exhibits Anti-viral and Anti-inflammatory Activity in COVID-19-Associated Inflammation by Regulating NLRP3 Inflammasomes

IF4.3

2023-01-069

OAAI

ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications

CANCER GENE THERAPY

IF5

2022-07-225

PRE

Forging of nicotine for the effective management of diabetic wounds: A hybrid of scaffold hopping and molecular dynamics simulation approaches

ARABIAN JOURNAL OF CHEMISTRY

IF5.2

2022-02-011

OAAI

Downregulation of ARID1B, a tumor suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways

HUMAN MOLECULAR GENETICS

IF3.2

2021-05-059

PREAI

HISTome2: a database of histone proteins, modifiers for multiple organisms and epidrugs

EPIGENETICS & CHROMATIN

IF3.5

2020-08-0329

OAAI

Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas

miR-204表达的下调定义了第3组/第4组髓母细胞瘤的高度侵袭性子集

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2019-04-0321

OAAI

Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics (vol 10, 48, 2017)

EPIGENETICS & CHROMATIN

IF3.5

2018-11-161

OAAI

Studies of protein-protein interactions in Fanconi anemia pathway to unravel the DNA interstrand crosslink repair mechanism

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IF8.5

2017-11-014

PREAI

Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics

EPIGENETICS & CHROMATIN

IF3.5

2017-10-1815

OAAI

Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50

SCIENTIFIC REPORTS

IF3.9

2017-06-2061

OAAI

Understanding quasi-apoptosis of the most numerous enucleated components of blood needs detailed molecular autopsy

AGEING RESEARCH REVIEWS

IF12.4

2017-05-0122

PREAI

HIstome-a relational knowledgebase of human histone proteins and histone modifying enzymes

NUCLEIC ACIDS RESEARCH

IF13.1

2011-12-02112

OAAI