Winfried Hinrichs - Publications, H-index & Citations

Winfried Hinrichs

Universitat Greifswald

38H指数

202论文数

4.9K被引数

收录论文 35

发表时间

Time-resolved crystallography of boric acid binding to the active site serine of the β-lactamase CTX-M-14 and subsequent 1,2-diol esterification

COMMUNICATIONS CHEMISTRY

IF6.2

2024-07-05

OAAI

Prester, Andreas; Perbandt, Markus; Galchenkova, Marina; Oberthuer, Dominik; Werner, Nadine; Henkel, Alessandra; Maracke, Julia; Yefanov, Oleksandr; Hakanpaeae, Johanna; Pompidor, Guillaume; Meyer, Jan; Chapman, Henry; Aepfelbacher, Martin; Hinrichs, Winfried; Rohde, Holger; Betzel, Christian

SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds

NATURE COMMUNICATIONS

IF15.7

2024-05-07

OAAI

Reinke, Patrick Y. A.; Schubert, Robin; Oberthuer, Dominik; Galchenkova, Marina; Mashhour, Aida Rahmani; Guenther, Sebastian; Chretien, Anais; Round, Adam; Seychell, Brandon Charles; Norton-Baker, Brenna; Kim, Chan; Schmidt, Christina; Koua, Faisal H. M.; Tolstikova, Alexandra; Ewert, Wiebke; Murillo, Gisel Esperanza Pena; Mills, Grant; Kirkwood, Henry; Brognaro, Hevila; Han, Huijong; Koliyadu, Jayanath; Schulz, Joachim; Bielecki, Johan; Lieske, Julia; Maracke, Julia; Knoska, Juraj; Lorenzen, Kristina; Brings, Lea; Sikorski, Marcin; Kloos, Marco; Vakili, Mohammad; Vagovic, Patrik; Middendorf, Philipp; de Wijn, Raphael; Bean, Richard; Letrun, Romain; Han, Seonghyun; Falke, Sven; Geng, Tian; Sato, Tokushi; Srinivasan, Vasundara; Kim, Yoonhee; Yefanov, Oleksandr M.; Gelisio, Luca; Beck, Tobias; Dore, Andrew S.; Mancuso, Adrian P.; Betzel, Christian; Bajt, Sasa; Redecke, Lars; Chapman, Henry N.; Meents, Alke; Turk, Dusan; Hinrichs, Winfried; Lane, Thomas J.

Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-04-17

OAAI

Falke, Sven; Lieske, Julia; Herrmann, Alexander; Loboda, Jure; Karnicar, Katarina; Guenther, Sebastian; Reinke, Patrick Y. A.; Ewert, Wiebke; Usenik, Aleksandra; Lindic, Natasa; Sekirnik, Andreja; Dretnik, Klemen; Tsuge, Hideaki; Turk, Vito; Chapman, Henry N.; Hinrichs, Winfried; Ebert, Gregor; Turk, Dusan; Meents, Alke

Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections

COMMUNICATIONS BIOLOGY

IF5.1

2023-10-18

OAAI

Reinke, Patrick Y. A.; de Souza, Edmarcia Elisa; Guenther, Sebastian; Falke, Sven; Lieske, Julia; Ewert, Wiebke; Loboda, Jure; Herrmann, Alexander; Mashhour, Aida Rahmani; Karnicar, Katarina; Usenik, Aleksandra; Lindic, Natasa; Sekirnik, Andreja; Botosso, Viviane Fongaro; Santelli, Glaucia Maria Machado; Kapronezai, Josana; de Araujo, Marcelo Valdemir; Silva-Pereira, Taiana Taina; de Souza Filho, Antonio Francisco; Tavares, Mariana Silva; Florez-Alvarez, Lizdany; de Oliveira, Danielle Bruna Leal; Durigon, Edison Luiz; Giaretta, Paula Roberta; Heinemann, Marcos Bryan; Hauser, Maurice; Seychell, Brandon; Boehler, Hendrik; Rut, Wioletta; Drag, Marcin; Beck, Tobias; Cox, Russell; Chapman, Henry N.; Betzel, Christian; Brehm, Wolfgang; Hinrichs, Winfried; Ebert, Gregor; Latham, Sharissa L.; de Sa Guimaraes, Ana Marcia; Turk, Dusan; Wrenger, Carsten; Meents, Alke

Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus

MOLECULES

IF4.6

2022-11-16

OAAI

Palm, Gottfried J.; Thomsen, Maren; Berndt, Leona; Hinrichs, Winfried

Crystal structures of free and ligand-bound forms of the TetR/AcrR-like regulator SCO3201 from Streptomyces coelicolor suggest a novel allosteric mechanism

FEBS JOURNAL

IF4.2

2022-09-02

OAAI

Werten, Sebastiaan; Waack, Paul; Palm, Gottfried J.; Virolle, Marie-Joelle; Hinrichs, Winfried

Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease

COMMUNICATIONS BIOLOGY

IF5.1

2022-08-11

OAAI

Srinivasan, Vasundara; Brognaro, Hevila; Prabhu, Prince R.; de Souza, Edmarcia Elisa; Guenther, Sebastian; Reinke, Patrick Y. A.; Lane, Thomas J.; Ginn, Helen; Han, Huijong; Ewert, Wiebke; Sprenger, Janina; Koua, Faisal H. M.; Falke, Sven; Werner, Nadine; Andaleeb, Hina; Ullah, Najeeb; Franca, Bruno Alves; Wang, Mengying; Barra, Angelica Luana C.; Perbandt, Markus; Schwinzer, Martin; Schmidt, Christina; Brings, Lea; Lorenzen, Kristina; Schubert, Robin; Guaragna Machado, Rafael Rahal; Candido, Erika Donizette; Leal Oliveira, Danielle Bruna; Durigon, Edison Luiz; Niebling, Stephan; Garcia, Angelica Struve; Yefanov, Oleksandr; Lieske, Julia; Gelisio, Luca; Domaracky, Martin; Middendorf, Philipp; Groessler, Michael; Trost, Fabian; Galchenkova, Marina; Mashhour, Aida Rahmani; Saouane, Sofiane; Hakanpaeae, Johanna; Wolf, Markus; Alai, Maria Garcia; Turk, Dusan; Pearson, Arwen R.; Chapman, Henry N.; Hinrichs, Winfried; Wrenger, Carsten; Meents, Alke; Betzel, Christian

Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease

FRONTIERS IN CHEMISTRY

IF4.2

2022-04-11

OAAI

Ewert, Wiebke; Guenther, Sebastian; Miglioli, Francesca; Falke, Sven; Reinke, Patrick Y. A.; Niebling, Stephan; Guenther, Christian; Han, Huijong; Srinivasan, Vasundara; Brognaro, Hevila; Lieske, Julia; Lorenzen, Kristina; Garcia-Alai, Maria M.; Betzel, Christian; Carcelli, Mauro; Hinrichs, Winfried; Rogolino, Dominga; Meents, Alke

Structural basis to repurpose boron-based proteasome inhibitors Bortezomib and Ixazomib as β-lactamase inhibitors

SCIENTIFIC REPORTS

IF3.9

2022-04-01

OAAI

Perbandt, Markus; Werner, Nadine; Prester, Andreas; Rohde, Holger; Aepfelbacher, Martin; Hinrichs, Winfried; Betzel, Christian

The induction mechanism of the flavonoid-responsive regulator FrrA 类黄酮响应调节剂FrrA的诱导机制

FEBS JOURNAL

IF4.2

2021-08-02

PREAI

Werner, Nadine; Werten, Sebastiaan; Hoppen, Jens; Palm, Gottfried J.; Goettfert, Michael; Hinrichs, Winfried

The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity

SCIENTIFIC REPORTS

IF3.9

2021-06-10

OAAI

Werner, Nadine; Petersen, Katrin; Vollstedt, Christel; Garcia, Pablo Perez; Chow, Jennifer; Ferrer, Manuel; Fernandez-Lopez, Laura; Falke, Sven; Perbandt, Markus; Hinrichs, Winfried; Betzel, Christian; Streit, Wolfgang R.

Structural and biochemical analysis of a phosin from Streptomyces chartreusis reveals a combined polyphosphate- and metal-binding fold

FEBS LETTERS

IF3

2019-06-17

OAAI

Werten, Sebastiaan; Rustmeier, Nils Hinnerk; Gemmer, Maximilian; Virolle, Marie-Joelle; Hinrichs, Winfried

Assemblins as maturational proteases in herpesviruses

JOURNAL OF GENERAL VIROLOGY

IF4.3

2017-08-01

OAAI

Zuehlsdorf, Martin; Hinrichs, Winfried

Blocking tetracycline destruction

NATURE CHEMICAL BIOLOGY

IF13.7

2017-05-08

PREAI

Petkovic, Sonja; Hinrichs, Winfried

Structural evidence of intramolecular propeptide inhibition of the aspzincin metalloendopeptidase AsaP1

FEBS LETTERS

IF3

2016-09-06

OAAI

Bogdanovic, Xenia; Palm, Gottfried J.; Schwenteit, Johanna; Singh, Rajesh K.; Gudmundsdottir, Bjarnheidur K.; Hinrichs, Winfried

Modular organisation of inducer recognition and allostery in the tetracycline repressor

FEBS JOURNAL

IF4.2

2016-04-20

OAAI

Werten, Sebastiaan; Schneider, Julia; Palm, Gottfried Julius; Hinrichs, Winfried

Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease

PLOS PATHOGENS

IF4.9

2015-07-10

OAAI

Zuehlsdorf, Martin; Werten, Sebastiaan; Klupp, Barbara G.; Palm, Gottfried J.; Mettenleiter, Thomas C.; Hinrichs, Winfried

Structural and biochemical characterization of the dual substrate recognition of the (R)-selective amine transaminase from Aspergillus fumigatus

FEBS JOURNAL

IF4.2

2014-12-02

PREAI

Skalden, Lilly; Thomsen, Maren; Hoehne, Matthias; Bornscheuer, Uwe T.; Hinrichs, Winfried

Post-translational modification and extended glycosylation pattern of a plant latex peroxidase of native source characterized by X-ray crystallography

FEBS JOURNAL

IF4.2

2014-08-08

OAAI

Palm, Gottfried J.; Sharma, Anurag; Kumari, Moni; Panjikar, Santosh; Albrecht, Dirk; Jagannadham, Medicherla V.; Hinrichs, Winfried

Enzymatic Conversion of Flavonoids using Bacterial Chalcone Isomerase and Enoate Reductase

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2013-12-20

PREAI

Gall, Mechthild; Thomsen, Maren; Peters, Christin; Pavlidis, Ioannis V.; Jonczyk, Patrick; Gruenert, Philipp P.; Beutel, Sascha; Scheper, Thomas; Gross, Egon; Backes, Michael; Geissler, Torsten; Ley, Jakob P.; Hilmer, Jens-Michael; Krammer, Gerhard; Palm, Gottfried J.; Hinrichs, Winfried; Bornscheuer, Uwe T.

研究方向