Heung‐Chin Cheng - Publications, H-index & Citations

Heung‐Chin Cheng

university of melbourne

31H指数

90论文数

3.7K被引数

收录论文 27

发表时间

N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection 兴奋性毒性过程中神经元的N末端变化揭示了与突触功能障碍相关的蛋白水解事件和神经保护的潜在靶标

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2023-05-01

OAAI

Ameen, S. Sadia; Griem-Krey, Nane; Dufour, Antoine; Hossain, M. Iqbal; Hoque, Ashfaqul; Sturgeon, Sharelle; Nandurkar, Harshal; Draxler, Dominik F.; Medcalf, Robert L.; Kamaruddin, Mohd Aizuddin; Lucet, Isabelle S.; Leeming, Michael G.; Liu, Dazhi; Dhillon, Amardeep; Lim, Jet Phey; Basheer, Faiza; Zhu, Hong-Jian; Bokhari, Laita; Roulston, Carli L.; Paradkar, Prasad N.; Kleifeld, Oded; Clarkson, Andrew N.; Wellendorph, Petrine; Ciccotosto, Giuseppe D.; Williamson, Nicholas A.; Ang, Ching-Seng; Cheng, Heung-Chin

The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2023-04-07

OAAI

Griem-Krey, Nane; Klein, Anders B.; Clausen, Bettina H.; Namini, Mathias R. J.; Nielsen, Pernille, V; Bhuiyan, Mozammel; Nagaraja, Raghavendra Y.; De Silva, T. Michael; Sobey, Christopher G.; Cheng, Heung-Chin; Orset, Cyrille; Vivien, Denis; Lambertsen, Kate L.; Clarkson, Andrew N.; Wellendorph, Petrine

CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation

ONCOGENE

IF7.3

2021-03-25

PREAI

Chueh, Anderly C.; Advani, Gahana; Foroutan, Momeneh; Smith, Jai; Ng, Nadia; Nandurkar, Harshal; Lio, Daisy S.; Zhu, Hong-Jian; Chong, Yuh-Ping; Verkade, Heather; Fujita, Donald J.; Bjorge, Jeffrey; Basheer, Faiza; Lim, Jet Phey; Luk, Ian; Dhillon, Amardeep; Sakthianandeswaren, Anuratha; Mouradov, Dmitri; Sieber, Oliver; Hollande, Frederic; Mariadason, John M.; Cheng, Heung-Chin

The structure of the extracellular domains of human interleukin 11? receptor reveals mechanisms of cytokine engagement

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-06-01

OAAI

Metcalfe, Riley D.; Aizel, Kaheina; Zlatic, Courtney O.; Nguyen, Paul M.; Morton, Craig J.; Lio, Daisy Sio-Seng; Cheng, Heung-Chin; Dobson, Renwick C. J.; Parker, Michael W.; Gooley, Paul R.; Putoczki, Tracy L.; Griffin, Michael D. W.

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

SCIENTIFIC REPORTS

IF3.9

2019-05-07

OAAI

Ku, Matthew; MacKinnon, Ruth N.; Wall, Meaghan; Narayan, Nisha; Walkley, Carl; Cheng, Heung-Chin; Campbell, Lynda J.; Purton, Louise E.; Nandurkar, Harshal

Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

CELL DEATH & DISEASE

IF9.6

2019-03-01

OAAI

Hoque, Ashfaqul; Williamson, Nicholas A.; Ameen, S. Sadia; Ciccotosto, Giuseppe D.; Hossain, M. Iqbal; Oakhill, Jonathan S.; Ng, Dominic C. H.; Ang, Ching-Seng; Cheng, Heung-Chin

Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine

CELL COMMUNICATION AND SIGNALING

IF8.9

2017-08-07

OAAI

Advani, Gahana; Lim, Ya Chee; Catimel, Bruno; Lio, Daisy Sio Seng; Ng, Nadia L. Y.; Chueh, Anderly C.; Tran, Mai; Anasir, Mohd Ishtiaq; Verkade, Heather; Zhu, Hong-Jian; Turk, Benjamin E.; Smithgall, Thomas E.; Ang, Ching-Seng; Griffin, Michael; Cheng, Heung-Chin

A beacon of hope in stroke therapy Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies

PHARMACOLOGY & THERAPEUTICS

IF12.5

2016-04-01

PREAI

Hoque, Ashfaqul; Hossain, M. Iqbal; Ameen, S. Sadia; Ang, Ching-Seng; Williamson, Nicholas; Ng, Dominic C. H.; Chueh, Anderly C.; Roulston, Carli; Cheng, Heung-Chin

Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2016-01-20

OAAI

Cheung, NS; Choy, MS; Halliwell, B; Teo, TS; Bay, BH; Lee, AYW; Qi, RZ; Koh, VH; Whiteman, M; Koay, ESC; Chiu, LL; Zhu, HJ; Wong, KP; Beart, PM; Cheng, HC

The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

IF3

2015-12-01

PREAI

Chia, Yeong-Chit Joel; Catimel, Bruno; Lio, Daisy Sio Seng; Ang, Ching-Seng; Peng, Benjamin; Wu, Hong; Zhu, Hong-Jian; Cheng, Heung-Chin

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases. (vol 281, pg 32988, 2006)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-01-01

OAAI

Chong, Yuh-Ping; Chan, Andrew S.; Chan, Khai-Chew; Williamson, Nicholas A.; Lerner, Edwina C.; Smithgall, Thomas E.; Bjorge, Jeffrey D.; Fujita, Donald J.; Purcell, Anthony W.; Scholz, Glen; Mulhern, Terrence D.; Cheng, Heung-Chin

Global Analysis of Human Nonreceptor Tyrosine Kinase Specificity Using High-Density Peptide Microarrays

JOURNAL OF PROTEOME RESEARCH

IF3.6

2014-08-28

OAAI

Deng, Yang; Alicea-Velazquez, Nilda L.; Bannwarth, Ludovic; Lehtonen, Soili I.; Boggon, Titus J.; Cheng, Heung-Chin; Hytonen, Vesa P.; Turk, Benjamin E.

Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2)

HUMAN MUTATION

IF3.7

2014-02-24

OAAI

Mills, Ryan D.; Mulhern, Terrence D.; Liu, Fei; Culvenor, Janetta G.; Cheng, Heung-Chin

A Truncated Fragment of Src Protein Kinase Generated by Calpain-mediated Cleavage Is a Mediator of Neuronal Death in Excitotoxicity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-04-01

OAAI

Hossain, M. Iqbal; Roulston, Carli L.; Kamaruddin, M. Aizuddin; Chu, Percy W. Y.; Ng, Dominic C. H.; Dusting, Gregory J.; Bjorge, Jeffrey D.; Williamson, Nicholas A.; Fujita, Donald J.; Cheung, Steve N.; Chan, Tung O.; Hill, Andrew F.; Cheng, Heung-Chin

Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2012-09-19

PREAI

Mills, Ryan D.; Mulhern, Terrence D.; Cheng, Heung-Chin; Culvenor, Janetta G.

Analysis of the Regulatory and Catalytic Domains of PTEN-Induced Kinase-1 (PINK1)

HUMAN MUTATION

IF3.7

2012-07-05

OAAI

Sim, Chou Hung; Gabriel, Kipros; Mills, Ryan D.; Culvenor, Janetta G.; Cheng, Heung-Chin

Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide

BIOCHEMICAL JOURNAL

IF4.3

2011-02-24

PREAI

Ngoei, Kevin R. W.; Catimel, Bruno; Church, Nicole; Lio, Daisy S.; Dogovski, Con; Perugini, Matthew A.; Watt, Paul M.; Cheng, Heung-Chin; Ng, Dominic C. H.; Bogoyevitch, Marie A.

Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2)

NUCLEIC ACIDS RESEARCH

IF13.1

2007-11-13

OAAI

Gunawardana, Dilantha; Cheng, Heung-Chin; Gayler, Kenwyn R.

Decreased CHK protein levels are associated with Src activation in colon cancer cells

ONCOGENE

IF7.3

2007-10-15

PREAI

Zhu, S.; Bjorge, J. D.; Cheng, H. C.; Fujita, D. J.

PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid - Mechanistic analysis of a familial Cowden disease-associated PTEN mutation

CELLULAR SIGNALLING

IF3.7

2007-07-01

PREAI

Xiao, Yi; Chia, Joel Yeong Chit; Gajewski, Joanna E.; Lio, Daisy Sio Seng; Mulhern, Terrence D.; Zhu, Hong-Jian; Nandurkar, Harshal; Cheng, Heung-Chin

研究方向