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A broadly-neutralizing antibody against Orthoebolavirus glycoprotein that potentiates the breadth and neutralization of other antibodies 针对正埃博拉病毒糖蛋白的广谱中和抗体，其能增强其他抗体的广谱性和中和活性 Donnellan, Francesca R.; Rayaprolu, Vamseedhar; Rijal, Pramila; O'Dowd, Victoria; Parvate, Amar; Callaway, Heather; Hariharan, Chitra; Parekh, Dipti; Hui, Sean; Shaffer, Kelly C. L.; Avalos, Ruben Diaz; Hastie, Kathryn M.; Schimanski, Lisa; Muller-Krauter, Helena; Strecker, Thomas; Balaram, Ariane; Halfmann, Peter; Saphire, Erica Ollmann; Lightwood, Daniel J.; Townsend, Alain R.; Draper, Simon J. 分享 收藏
Obesity Alters the Metabolic and Immunologic Response of Pulmonary T Cells to SARS-CoV-2 Infection Kumar Verma, Shailendra; Timis, Julia; Maule, Erin; Ngono, Annie Elong; Ana-Sosa-Batiz, Fernanda; Miller, Robyn; Hastie, Kathryn; Saphire, Erica Ollmannn; Kim, Kenneth; Riffelmacher, Thomas; Shresta, Sujan 分享 收藏
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Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials 一种基于复制性-vesicular stomatitis virus的拉沙病毒疫苗候选物的临床前开发已进入人体临床试验阶段。 Cooper, Christopher L.; Morrow, Gavin; Yuan, Maoli; Postler, Thomas S.; Neal, Maxwell L.; Cross, Robert W.; Woolsey, Courtney; Agans, Krystle N.; Borisevich, Viktoriya; Mcnamara, Ryan P.; Atyeo, Caroline; Roy, Vicky; Germosen, Daritza; Hou, Fuxiang; Li, Shui L.; Reiserova, Lucia; Choi, Yesle; Wilson, Aaron; Wagner, Denise; Wallace-Selman, Olivia; Carpov, Alexei; Geng, Fuqiang; Frederick, Deborah J.; Destefano, Joanne; Ercolini, Anne M.; Enriquez, Adrian S.; Hastie, Kathryn M.; Silva, Suzane Ramos da; Sayeed, Eddy; Coleman, John W.; Kilianski, Andrew; Alter, Galit; Saphire, Erica Ollmann; Aitchison, John D.; Geisbert, Thomas W.; Gupta, Swati B.; Feinberg, Mark B.; Parksa, Christopher L. 分享 收藏
A global collaboration for systematic analysis of broad-ranging antibodies against the SARS-CoV-2 spike protein 一项全球合作，用于对针对SARS-CoV-2刺突蛋白的广谱抗体的系统分析 Schendel, Sharon L.; Yu, Xiaoying; Halfmann, Peter J.; Mahita, Jarjapu; Ha, Brendan; Hastie, Kathryn M.; Li, Haoyang; Bedinger, Daniel; Troup, Camille; Li, Kan; Kuzmina, Natalia; Torrelles, Jordi B.; Munt, Jennifer E.; Maddocks, Melissa; Osei-Twum, Mary; Callaway, Heather M.; Reece, Stephen; Palser, Anne; Kellam, Paul; Dennison, S. Moses; Huntwork, Richard H. C.; Horn, Gillian Q.; Abraha, Milite; Feeney, Elizabeth; Martinez-Sobrido, Luis; Pino, Paula A.; Hicks, Amberlee; Ye, Chengjin; Park, Jun-Gyu; Maingot, Billie; Periasamy, Sivakumar; Mallory, Michael; Scobey, Trevor; Lepage, Marie-Noelle; St-Amant, Natalie; Khan, Sarwat; Gambiez, Anais; Baric, Ralph S.; Bukreyev, Alexander; Gagnon, Luc; Germann, Timothy; Kawaoka, Yoshihiro; Tomaras, Georgia D.; Peters, Bjoern; Saphire, Erica Ollmann 分享 收藏
A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity 人源化ACE2、TMPRSS2和FCGRT小鼠模型揭示了由SARS-CoV-2混合免疫力诱导的抗受体结合域抗体的保护效力 Ana-Sosa-Batiz, Fernanda; Verma, Shailendra Kumar; Shafee, Norazizah; Miller, Robyn; Conner, Chris; Hastie, Kathryn M.; Timis, Julia; Maule, Erin; Nguyen, Michael N.; Tran, Linda; Varghese, Krithik; Madany, Henry; Street, Audrey Elizabeth; Zandonatti, Michelle; Moi, Meng Ling; Jarnagin, Kurt; Webb, David R.; Saphire, Erica Ollmann; Kim, Kenneth; Shrestaa, Sujan 分享 收藏
Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane 抗埃博拉病毒单克隆抗体3A6通过结合位于病毒颗粒膜上方位置的GP(1,2)，保护高病毒血症动物免于致命结局。 Hastie, Kathryn M.; Salie, Zhe Li; Halfmann, Peter J.; Dewald, Lisa Evans; Mcardle, Sara; Grinyo, Ariadna; Davidson, Edgar; Schendel, Sharon L.; Hariharan, Chitra; Norris, Michael J.; Yu, Xiaoying; Chennareddy, Chakravarthy; Xiong, Xiaoli; Heinrich, Megan; Holbrook, Michael R.; Doranz, Benjamin; Crozier, Ian; Kawaoka, Yoshihiro; Branco, Luis M.; Kuhn, Jens H.; Briggs, John A. G.; Davis, Carl W.; Ahmed, Rafi; Saphire, Erica Ollmann 分享 收藏
Co-immunization with spike and nucleocapsid based DNA vaccines for long-term protective immunity against SARS-CoV-2 Omicron 与基于刺突和核衣壳的DNA疫苗共同预防接种，用于对SARS-CoV-2 Omicron的长期保护性免疫 Pinto, Paolla Beatriz Almeida; Timis, Julia; Chuensirikulchai, Kantinan; Li, Qin Hui; Lu, Hsueh Han; Maule, Erin; Nguyen, Michael; Alves, Rubens Prince dos Santos; Verma, Shailendra Kumar; Ana-Sosa-Batiz, Fernanda; Valentine, Kristen; Landeras-Bueno, Sara; Kim, Kenneth; Hastie, Kathryn; Saphire, Erica Ollmann; Alves, Ada; Ngono, Annie Elong; Shresta, Sujan 分享 收藏
Influence fl uence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice Verma, Shailendra Kumar; Ana-Sosa-Batiz, Fernanda; Timis, Julia; Shafee, Norazizah; Maule, Erin; Pinto, Paolla Beatriz Almeida; Conner, Chris; Valentine, Kristen M.; Cowley, Dale O.; Miller, Robyn; Ngono, Annie Elong; Tran, Linda; Varghese, Krithik; Alves, Rubens Prince Dos Santos; Hastie, Kathryn M.; Saphire, Erica Ollmann; Webb, David R.; Jarnagin, Kurt; Kim, Kenneth; Shresta, Sujan 分享 收藏
Identification of mouse CD4+ T cell epitopes in SARS-CoV-2 BA.1 spike and nucleocapsid for use in peptide:MHCII tetramers Bricio-Moreno, Laura; de Albuquerque, Juliana Barreto; Neary, Jake M.; Nguyen, Thao; Kuhn, Lucy F.; Yeung, Yeepui; Hastie, Kathryn M.; Landeras-Bueno, Sara; Olmedillas, Eduardo; Hariharan, Chitra; Nathan, Anusha; Getz, Matthew A.; Gayton, Alton C.; Khatri, Ashok; Gaiha, Gaurav D.; Saphire, Erica Ollmann; Luster, Andrew D.; Moon, James J. 分享 收藏
Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants Li, Kan; Huntwork, Richard H. C.; Horn, Gillian Q.; Abraha, Milite; Hastie, Kathryn M.; Li, Haoyang; Rayaprolu, Vamseedhar; Olmedillas, Eduardo; Feeney, Elizabeth; Cronin, Kenneth; Schendel, Sharon L.; Heise, Mark; Bedinger, Daniel; Mattocks, Melissa D.; Baric, Ralph S.; Alam, S. Munir; Ollmann Saphire, Erica; Tomaras, Georgia D.; Dennison, S. Moses 分享 收藏
The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus Yu, Xiaoying; Hastie, Kathryn M.; Davis, Carl W.; Avalos, Ruben Diaz; Williams, Dewight; Parekh, Diptiben; Hui, Sean; Mann, Colin; Hariharan, Chitra; Takada, Ayato; Ahmed, Rafi; Saphire, Erica Ollmann 分享 收藏
The Arenaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens Hastie, Kathryn M.; Melnik, Lilia, I; Cross, Robert W.; Klitting, Raphaelle M.; Andersen, Kristian G.; Saphire, Erica Ollmann; Garry, Robert F. 分享 收藏
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