未登录 分享 收藏
CDK8 inhibitor KY-065 rescues skeletal abnormalities in achondroplasia model mice CDK8抑制剂KY-065可纠正软骨发育不全模型小鼠的骨骼异常 Sadamori, Koki; Kubo, Takuya; Yoshida, Tomoki; Yamamoto, Megumi; Shibata, Yui; Fukasawa, Kazuya; Tokumura, Kazuya; Horie, Tetsuhiro; Kadota, Takuya; Yamakawa, Ryotaro; Hojo, Hironori; Tanaka, Nobutada; Kitao, Tatsuya; Shirahase, Hiroaki; Hinoi, Eiichi 分享 收藏
分享 收藏
Expanding the Chemical Space of Reverse Fosmidomycin Analogs Knak, Talea; Takada, Sana; Illarionov, Boris; Krisilia, Violetta; de Carvalho, Lais Pessanha; Lungerich, Beate; Sakamoto, Yasumitsu; Hoefmann, Stefan; Bacher, Adelbert; Kalscheuer, Rainer; Held, Jana; Fischer, Markus; Tanaka, Nobutada; Kurz, Thomas 分享 收藏
Reverse N-Substituted Hydroxamic Acid Derivatives of Fosmidomycin Target a Previously Unknown Subpocket of 1-Deoxy-D-xylulose 5-Phosphate Reductoisomerase (DXR) Abdullaziz, Mona A.; Takada, Sana; Illarionov, Boris; Pessanha de Carvalho, Lais; Sakamoto, Yasumitsu; Ho''fmann, Stefan; Knak, Talea; Kiffe-Delf, Anna-Lene; Mazzone, Flaminia; Pfeffer, Klaus; Kalscheuer, Rainer; Bacher, Adelbert; Held, Jana; Fischer, Markus; Tanaka, Nobutada; Kurz, Thomas 分享 收藏
Design and Pharmacological Chaperone Effects of N-(4′-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase Kato, Atsushi; Nakagome, Izumi; Kise, Maki; Yoshimura, Kousuke; Tanaka, Nobutada; Nash, Robert J.; Fleet, George W. J.; Kobayashi, Yota; Ikeda, Hayato; Okada, Takuya; Toyooka, Naoki 分享 收藏
分享 收藏
5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease Kato, Atsushi; Nakagome, Izumi; Kanekiyo, Uta; Lu, Tian-Tian; Li, Yi-Xian; Yoshimura, Kosuke; Kishida, Mana; Shinzawa, Kenta; Yoshida, Tomoki; Tanaka, Nobutada; Jia, Yue-Mei; Nash, Robert J.; Fleet, George W. J.; Yu, Chu-Yi 分享 收藏
分享 收藏
Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7 Nakamura, Akihiro; Suzuki, Yoshiyuki; Sakamoto, Yasumitsu; Roppongi, Saori; Kushibiki, Chisato; Yonezawa, Natsuri; Takahashi, Masato; Shida, Yosuke; Gouda, Hiroaki; Nonaka, Takamasa; Tanaka, Nobutada; Ogasawara, Wataru 分享 收藏
Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase Sakamoto, Yasumitsu; Suzuki, Yoshiyuki; Nakamura, Akihiro; Watanabe, Yurie; Sekiya, Mizuki; Roppongi, Saori; Kushibiki, Chisato; Iizuka, Ippei; Tani, Osamu; Sakashita, Hitoshi; Inaka, Koji; Tanaka, Hiroaki; Yamada, Mitsugu; Ohta, Kazunori; Honma, Nobuyuki; Shida, Yosuke; Ogasawara, Wataru; Nakanishi-Matsui, Mayumi; Nonaka, Takamasa; Gouda, Hiroaki; Tanaka, Nobutada 分享 收藏
Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues Roppongi, Saori; Suzuki, Yoshiyuki; Tateoka, Chika; Fujimoto, Mayu; Morisawa, Saori; Iizuka, Ippei; Nakamura, Akihiro; Honma, Nobuyuki; Shida, Yosuke; Ogasawara, Wataru; Tanaka, Nobutada; Sakamoto, Yasumitsu; Nonaka, Takamasa 分享 收藏
The impact of a single-nucleotide mutation of bgl2 on cellulase induction in a Trichoderma reesei mutant Shida, Yosuke; Yamaguchi, Kaori; Nitta, Mikiko; Nakamura, Ayana; Takahashi, Machiko; Kidokoro, Shun-ichi; Mori, Kazuki; Tashiro, Kosuke; Kuhara, Satoru; Matsuzawa, Tomohiko; Yaoi, Katsuro; Sakamoto, Yasumitsu; Tanaka, Nobutada; Morikawa, Yasushi; Ogasawara, Wataru 分享 收藏
分享 收藏
Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity Sakamoto, Yasumitsu; Suzuki, Yoshiyuki; Iizuka, Ippei; Tateoka, Chika; Roppongi, Saori; Fujimoto, Mayu; Inaka, Koji; Tanaka, Hiroaki; Yamada, Mitsugu; Ohta, Kazunori; Gouda, Hiroaki; Nonaka, Takamasa; Ogasawara, Wataru; Tanaka, Nobutada 分享 收藏
Binding Modes of Reverse Fosmidomycin Analogs toward the Antimalarial Target IspC Konzuch, Sarah; Umeda, Tomonobu; Held, Jana; Haehn, Saskia; Bruecher, Karin; Lienau, Claudia; Behrendt, Christoph T.; Graewert, Tobias; Bacher, Adelbert; Illarionov, Boris; Fischer, Markus; Mordmueller, Benjamin; Tanaka, Nobutada; Kurz, Thomas 分享 收藏
S46 Peptidases are the First Exopeptidases to be Members of Clan PA Sakamoto, Yasumitsu; Suzuki, Yoshiyuki; Iizuka, Ippei; Tateoka, Chika; Roppongi, Saori; Fujimoto, Mayu; Inaka, Koji; Tanaka, Hiroaki; Masaki, Mika; Ohta, Kazunori; Okada, Hirofumi; Nonaka, Takamasa; Morikawa, Yasushi; Nakamura, Kazuo T.; Ogasawara, Wataru; Tanaka, Nobutada 分享 收藏
分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
