Irini Doytchinova - Publications, H-index & Citations

Irini Doytchinova

Medical University Sofia

40H指数

173论文数

1.1W被引数

收录论文 51

发表时间

Design, Synthesis, and Integrated In Silico and In Vitro Evaluation of Chloro-Substituted Salicylaldehyde Benzoylhydrazones as Anticancer Agents 氯取代水杨醛苯甲酰肼类化合物的设计、合成及整合体外与计算机模拟评价作为抗癌药物

Pharmaceuticals

IF4.8

2026-09-02

OAAI

Boryana Nikolova-Mladenova; Rositsa Mihaylova; Stilyana Kostova; Boris Vasilev; Irini Doytchinova; Mariyana Atanasova

VaxiGen – a server for prediction of protective antigens of bacterial, viral, and tumor origin VaxiGen——一个用于预测来自细菌、病毒和肿瘤的保护性抗原的服务器

BMC Bioinformatics

IF3.3

2026-08-04

OAAI

Stanislav Sotirov; Nikolet Doneva-Tashkova; Nevena Zaharieva; Ivan Dimitrov; Irini Doytchinova

VaxiGen Database of Tumor Immunogens 肿瘤免疫原VaxiGen数据库

Data

IF2

2026-05-01

PREAI

Sotirov, Stanislav; Dimitrov, Ivan; Doytchinova, Irini

AI-Driven Identification of Candidate Peptides for Immunotherapy in Non-Obese Diabetic Mice: An In Silico Study 人工智能驱动的非肥胖糖尿病小鼠免疫治疗候选肽识别：一项计算机模拟研究

IF5

2026-04-15

OAAI

Irini Doytchinova; Ivan Dimitrov; Mariyana Atanasova; Nikolina M. Mihaylova; Andrey Tchorbanov

Rational Design, Synthesis, and Molecular Docking of Novel Terpene Analogues of Imatinib, and Their Inhibition on Downstream BCR-ABL Signaling 基于理性设计、合成及分子对接的新型伊马替尼类萜烯类似物，及其对下游BCR-ABL信号通路的抑制作用

Pharmaceuticals

IF4.8

2026-01-23

OAAI

Rositsa Mihaylova; Asine Dailova-Barzeva; Irena Philipova; Georgi Momekov; Irini Doytchinova; Mariyana Atanasova; Georgi Stavrakov

Novel Indole-Based Sulfonylhydrazones as Potential Anti-Breast Cancer Agents: Synthesis, In Vitro Evaluation, ADME, and QSAR Studies 新型吲哚基磺酰基 hydrazone 作为潜在抗乳腺癌药物：合成、体外评价、ADME 及 QSAR 研究

Pharmaceuticals 2025, Vol. 18, Page 1231

IF4.8

2025-08-20

PREAI

Violina T. Angelova; Rositsa Mihaylova; Zvetanka Zhivkova; Nikolay Vassilev; Boris Shivachev; Irini Doytchinova

Salicylaldehyde Benzoylhydrazones with Anticancer Activity and Selectivity: Design, Synthesis, and In Vitro Evaluation

MOLECULES

IF4.6

2025-02-22

OAAI

Nikolova-Mladenova, Boryana; Mihaylova, Rositsa; Atanasova, Mariyana; Zhivkova, Zvetanka; Doytchinova, Irini

Design, Development and Immunogenicity Study of a Multi-Epitope Vaccine Prototype Against SARS-CoV-2

PHARMACEUTICALS

IF4.8

2024-11-07

OAAI

Atanasova, Mariyana; Dimitrov, Ivan; Ralchev, Nikola; Markovski, Aleksandar; Manoylov, Iliyan; Bradyanova, Silviya; Mihaylova, Nikolina; Tchorbanov, Andrey; Doytchinova, Irini

In Silico Identification of Peanut Peptides Suitable for Allergy Immunotherapy in HLA-DRB1*03:01-Restricted Patients

PHARMACEUTICALS

IF4.8

2024-08-21

OAAI

Doytchinova, Irini; Atanasova, Mariyana; Sotirov, Stanislav; Dimitrov, Ivan

Modeling Peptide-Protein Interactions by a Logo-Based Method: Application in Peptide-HLA Binding Predictions

MOLECULES

IF4.6

2024-01-05

OAAI

Doytchinova, Irini; Atanasova, Mariyana; Fernandez, Antonio; Moreno, F. Javier; Koning, Frits; Dimitrov, Ivan

Assessment of Novel Proteins Triggering Celiac Disease via Docking-Based Approach

MOLECULES

IF4.6

2023-12-26

OAAI

Atanasova, Mariyana; Dimitrov, Ivan; Fernandez, Antonio; Moreno, Javier; Koning, Frits; Doytchinova, Irini

Novel Arylsulfonylhydrazones as Breast Anticancer Agents Discovered by Quantitative Structure-Activity Relationships 通过定量构效关系发现的作为乳腺癌抗癌剂的新型芳基磺酰hydr

MOLECULES

IF4.6

2023-02-22

OAAI

Angelova, Violina T. T.; Tatarova, Teodora; Mihaylova, Rositsa; Vassilev, Nikolay; Petrov, Boris; Zhivkova, Zvetanka; Doytchinova, Irini

A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-01-10

OAAI

Spassov, Danislav S.; Atanasova, Mariyana; Doytchinova, Irini

Peptide-based targeted cancer therapeutics: Design, synthesis and biological evaluation

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2022-09-01

PREAI

Iwanov, Iwan; Rossi, Arianna; Montesi, Monica; Doytchinova, Irini; Sargsyan, Armen; Momekov, Georgi; Panseri, Silvia; Naydenova, Emilia

Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening

MOLECULES

IF4.6

2022-08-26

OAAI

Spassov, Danislav S.; Atanasova, Mariyana; Doytchinova, Irini

Virtual Screening and Hit Selection of Natural Compounds as Acetylcholinesterase Inhibitors

MOLECULES

IF4.6

2022-05-13

OAAI

Atanasova, Mariyana; Dimitrov, Ivan; Ivanov, Stefan; Georgiev, Borislav; Berkov, Strahil; Zheleva-Dimitrova, Dimitrina; Doytchinova, Irini

Drug Design-Past, Present, Future

MOLECULES

IF4.6

2022-02-23

OAAI

Doytchinova, Irini

The Amaryllidaceae alkaloids: an untapped source of acetylcholinesterase inhibitors

PHYTOCHEMISTRY REVIEWS

IF7.6

2021-11-18

PREAI

Berkov, Strahil; Atanasova, Mariyana; Georgiev, Borislav; Bastida, Jaume; Doytchinova, Irini

Effects of Curcumin and Ferulic Acid on the Folding of Amyloid-β Peptide 姜黄素和阿魏酸对 β-淀粉样肽折叠的影响

MOLECULES

IF4.6

2021-05-10

OAAI

Salamanova, Evdokiya; Atanasova, Mariyana; Dimitrov, Ivan; Doytchinova, Irini

Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening

MOLECULES

IF4.6

2021-04-03

OAAI

Stavrakov, Georgi; Philipova, Irena; Lukarski, Atanas; Atanasova, Mariyana; Georgiev, Borislav; Atanasova, Teodora; Konstantinov, Spiro; Doytchinova, Irini

研究方向