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Alejandro J. Vila

national university of rosario

52H指数
292论文数
9.0K被引数
收录论文 130
发表时间
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Zinc starvation uncovers bacterial host-specific proteases that shape NDM adaptability in Acinetobacter baumannii锌缺乏揭示了鲍曼不动杆菌中特异性的细菌宿主蛋白酶，这些蛋白酶塑造了NDM的适应性。
errMBIO
IF4.7
err2025-12-01
err0
PREAI
errParodi, Clarisa; Saposnik, Lucas; Martino, Roman A.; Ramirez, Maria Soledad; Cassataro, Juliana; Smania, Andrea M.; Bonomo, Robert A.; Vila, Alejandro J.; Gonzalez, Lisandro J.
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Let’s Dance: How Protein Dynamics Drive β-Lactamase Evolution and Antibiotic Resistance?让我们跳舞：蛋白质动力学如何驱动β-内酰胺酶进化和抗生素抗性？
errBiochemistry
IF3
err2025-11-05
err0
PREAI
errBrenda A. Warecki; Diego M. Moreno; Robert A. Bonomo; Alejandro J. Vila
err分享
err收藏
NDM-driven cefiderocol resistance: effect and therapeutic considerationsNDM驱动的费地尔科洛尔耐药性：影响和治疗考量
errThe Lancet Infectious Diseases
IF0
err2025-08-11
err0
PREAI
errBrenda A Warecki; Pranita D Tamma; Robert A Bonomo; Alejandro J Vila
err分享
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Cefepime-Taniborbactam-a Novel Combination Therapy for Multidrug-Resistant Pathogens头孢吡肟-他尼巴坦—一种针对多重耐药病原体的新型联合疗法
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2025-05-12
err0
PREAI
errWatkins, Richard R.; Lemonovich, Tracy L.; Vila, Alejandro J.; Bonomo, Robert A.
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OXA β-lactamases from Acinetobacter spp. are membrane bound and secreted into outer membrane vesicles
errMBIO
IF4.7
err2025-02-05
err0
errOAAI
errCapodimonte, Lucia; Meireles, Fernando Teixeira Pinto; Bahr, Guillermo; Bonomo, Robert A.; Dal Peraro, Matteo; Lopez, Carolina; Vila, Alejandro J.
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Interactions of hydrolyzed β-lactams with the L1 metallo-β-lactamase: β-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products (Vol 300, 107819, 2024)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-10-01
err1
errOAAI
errHinchliffe, Philip; Calvopina, Karina; Rabe, Patrick; Mojica, Maria F.; Schofield, Christopher J.; Dmitrienko, Gary I.; Bonomo, Robert A.; Vila, Alejandro J.; Spencer, James
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The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-08-07
err0
PREAI
errOno, Daisuke; Cmolik, Anna; Bethel, Christopher R.; Ishii, Yoshikazu; Drusin, Salvador I.; Moreno, Diego M.; Vila, Alejandro J.; Bonomo, Robert A.; Mojica, Maria F.
err分享
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Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-02-19
err2
PREAI
errVillamil, Valentina; Rossi, Maria-Agustina; Mojica, Maria F.; Hinchliffe, Philip; Martinez, Veronica; Castillo, Valerie; Saiz, Cecilia; Banchio, Claudia; Macias, Mario A.; Spencer, James; Bonomo, Robert A.; Vila, Alejandro; Moreno, Diego M.; Mahler, Graciela
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err收藏
Relative inhibitory activities of the broad-spectrum β-lactamase inhibitor taniborbactam against metallo-β-lactamases
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-02-07
err15
errOAAI
errLe Terrier, Christophe; Viguier, Clement; Nordmann, Patrice; Vila, Alejandro J.; Poirel, Laurent
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Structural role of K224 in taniborbactam inhibition of NDM-1
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-02-07
err9
errOAAI
errOno, Daisuke; Mojica, Maria F.; Bethel, Christopher R.; Ishii, Yoshikazu; Drusin, Salvador I.; Moreno, Diego M.; Vila, Alejandro J.; Bonomo, Robert A.
err分享
err收藏
Structural basis of metallo-β-lactamase resistance to taniborbactam
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-02-07
err14
errOAAI
errDrusin, Salvador I.; Le Terrier, Christophe; Poirel, Laurent; Bonomo, Robert A.; Vila, Alejandro J.; Moreno, Diego M.
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The Real Crisis in Antimicrobial Resistance: Failure to Anticipate and Respond
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2024-01-30
err7
errOAAI
errBonomo, Robert A.; Perez, Federico; Hujer, Andrea M.; Hujer, Kristine M.; Vila, Alejandro J.
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In-cell kinetic stability is an essential trait in metallo-β-lactamase evolution
errNATURE CHEMICAL BIOLOGY
IF13.7
err2023-05-15
err9
PREAI
errGonzalez, Lisandro J.; Bahr, Guillermo; Gonzalez, Mariano M.; Bonomo, Robert A.; Vila, Alejandro J.
err分享
err收藏
Interactions of hydrolyzed β-lactams with the L1 metallo-β-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-05-01
err6
errOAAI
errHinchliffe, Philip; Calvopina, Karina; Rabe, Patrick; Mojica, Maria F.; Schofiled, Christopher J.; Dmitrienko, Gary I.; Bonomo, Robert A.; Vila, Alejandro J.; Spencer, James
err分享
err收藏
Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase
errELIFE
IF0
err2023-02-24
err3
errOAAI
errZhao, Zhuoran; Shen, Xiayu; Chen, Shuang; Gu, Jing; Wang, Haun; Mojica, Maria F.; Samanta, Moumita; Bhowmik, Debsindhu; Vila, Alejandro J.; Bonomo, Robert A.; Haider, Shozeb
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Characterization of a Novel Pathogen in Immunocompromised Patients: Elizabethkingia anophelis-Exploring the Scope of Resistance to Contemporary Antimicrobial Agents and 13-lactamase Inhibitors免疫功能低下患者中新型病原体的表征: Elizabethkingia按蚊-探索对当代抗菌剂和13-内酰胺酶抑制剂的耐药性范围
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2023-01-31
err5
errOAAI
errYasmin, Mohamad; Rojas, Laura J.; Marshall, Steven H.; Hujer, Andrea M.; Cmolik, Anna; Marshall, Emma; Boucher, Helen W.; Vila, Alejandro J.; Soldevila, Maxime; Diene, Seydina M.; Rolain, Jean-Marc; Bonomo, Robert A.
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The mitochondrial Cu plus transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err0
errOAAI
errQuinteros, Michael; Morgada, Marcos; Castelblanco, Aida; Davis, Emily; Hainer, Sarah; Vila, Alejandro; Navea, Juan; Padilla-Benevides, Teresita
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2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases (vol 12, pg 2898, 2021)
errCHEMICAL SCIENCE
IF7.4
err2023-01-01
err0
errOAAI
errRossi, Maria-Agustina; Martinez, Veronica; Hinchliffe, Philip; Mojica, Maria F.; Castillo, Valerie; Moreno, Diego M.; Smith, Ryan; Spellberg, Brad; Drusano, George L.; Banchio, Claudia; Bonomo, Robert A.; Spencer, James; Vila, Alejandro J.; Mahler, Graciela
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The mitochondrial Cu+ transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2022-11-09
err20
errOAAI
errMcCann, Cat; Quinteros, Michael; Adelugba, Ifeoluwa; Morgada, Marcos N.; Castelblanco, Aida R.; Davis, Emily J.; Lanzirotti, Antonio; Hainer, Sarah J.; Vila, Alejandro J.; Navea, Juan G.; Padilla-Benavides, Teresita
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Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams
errMBIO
IF4.7
err2022-10-26
err13
errOAAI
errColque, Claudia A.; Albarracin Orio, Andrea G.; Tomatis, Pablo E.; Dotta, Gina; Moreno, Diego M.; Hedemann, Laura G.; Hickman, Rachel A.; Sommer, Lea M.; Feliziani, Sofia; Moyano, Alejandro J.; Bonomo, Robert A.; Johansen, Helle K.; Molin, Soren; Vila, Alejandro J.; Smania, Andrea M.
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研究方向

暂无研究方向
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合作期刊
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