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收藏分享 收藏 Identification of the Novel Variants in Patients With Chronic Thromboembolic Pulmonary Hypertension
Yaoita, Nobuhiro; Satoh, Kimio; Satoh, Taijyu; Shimizu, Toru; Saito, Sakae; Sugimura, Koichiro; Tatebe, Shunsuke; Yamamoto, Saori; Aoki, Tatsuo; Kikuchi, Nobuhiro; Kurosawa, Ryo; Miyata, Satoshi; Nagasaki, Masao; Yasuda, Jun; Shimokawa, Hiroaki 分享 收藏 Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transductionSkalova, Tereza; Lengalova, Alzbeta; Dohnalek, Jan; Harlos, Karl; Mihalcin, Peter; Kolenko, Petr; Stranava, Martin; Blaha, Jan; Shimizu, Toru; Martinkova, Marketa 分享 收藏 Identification of Adipsin as a Novel Prognostic Biomarker in Patients With Coronary Artery Disease鉴定Adipsin作为冠心病患者的新型预后生物标志物Ohtsuki, Tomohiro; Satoh, Kimio; Shimizu, Toru; Ikeda, Shohei; Kikuchi, Nobuhiro; Satoh, Taijyu; Kurosawa, Ryo; Nogi, Masamichi; Sunamura, Shinichiro; Yaoita, Nobuhiro; Omura, Junichi; Aoki, Tatsuo; Tatebe, Shunsuke; Sugimura, Koichiro; Takahashi, Jun; Miyata, Satoshi; Shimokawa, Hiroaki 分享 收藏 Kinetic analysis of a globin-coupled diguanylate cyclase, YddV: Effects of heme iron redox state, axial ligands, and heme distal mutations on catalysisLengalova, Alzbeta; Fojtikova-Proskova, Veronika; Vavra, Jakub; Martinek, Vaclav; Stranava, Martin; Shimizu, Toru; Martinkova, Marketa 分享 收藏 Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in miceSunamura, Shinichiro; Satoh, Kimio; Kurosawa, Ryo; Ohtsuki, Tomohiro; Kikuchi, Nobuhiro; Elias-Al-Mamun, Md.; Shimizu, Toru; Ikeda, Shohei; Suzuki, Kota; Satoh, Taijyu; Omura, Junichi; Nogi, Masamichi; Numano, Kazuhiko; Siddique, Mohammad Abdul Hai; Miyata, Satoshi; Miura, Masahito; Shimokawa, Hiroaki 分享 收藏 Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transductionStranava, Martin; Man, Petr; Skalova, Tereza; Kolenko, Petr; Blaha, Jan; Fojtikova, Veronika; Martinek, Vaclav; Dohnalek, Jan; Lengalova, Alzbeta; Rosulek, Michal; Shimizu, Toru; Martinkova, Marketa 分享 收藏 分享 收藏 分享 收藏 Structural characterization of the heme-based oxygen sensor, AfGcHK, its interactions with the cognate response regulator, and their combined mechanism of action in a bacterial two-component signaling systemStranava, Martin; Martinek, Vaclav; Man, Petr; Fojtikova, Veronika; Kavan, Daniel; Vanek, Ondrej; Shimizu, Toru; Martinkova, Marketa 分享 收藏 分享 收藏 Crucial Roles of Rho-kinase, Cyclophilin A and its Receptor, Basigin, for Cardiac Hypertrophy, Fibrosis and Failure-Novel Therapeutic TargetsSatoh, Kimio; Suzuki, Kota; Sunamura, Shinichiro; Otsuki, Tomohiro; Shimizu, Toru; Ikeda, Shohei; Aoki, Tatsuo; Tatebe, Shunsuke; Sugimura, Koichiro; Shimokawa, Hiroaki 分享 收藏 Rho-Kinase Inhibition During Early Cardiac Development Causes Arrhythmogenic Right Ventricular Cardiomyopathy in MiceEllawindy, Alia; Satoh, Kimio; Sunamura, Shinichiro; Kikuchi, Nobuhiro; Suzuki, Kota; Minami, Tatsuro; Ikeda, Shohei; Tanaka, Shinichi; Shimizu, Toru; Enkhjargal, Budbazar; Miyata, Satoshi; Taguchi, Yuhto; Handoh, Tetsuya; Kobayashi, Kenta; Kobayashi, Kazuto; Nakayama, Keiko; Miura, Masahito; Shimokawa, Hiroaki 分享 收藏 分享 收藏 Introduction of water into the heme distal side by Leu65 mutations of an oxygen sensor, YddV, generates verdoheme and carbon monoxide, exerting the heme oxygenase reactionStranava, Martin; Martinkova, Marketa; Stiborova, Marie; Man, Petr; Kitanishi, Kenichi; Muchova, Lucie; Vitek, Libor; Martinek, Vaclav; Shimizu, Toru 分享 收藏 Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, EcDOS and YddV, have profound effects on their flexibilityAnzenbacher, Pavel; Marchal, Stephane; Palacky, Jan; Anzenbacherova, Eva; Domaschke, Thomas; Lange, Reinhard; Shimizu, Toru; Kitanishi, Kenichi; Stranava, Martin; Stiborova, Marie; Martinkova, Marketa 分享 收藏 Crucial Role of Rho-kinase in Pressure-overload-induced Right Ventricular Hypertrophy and Dysfunction in MiceIkeda, Shohei; Satoh, Kimio; Kikuchi, Nobuhiro; Miyata, Satoshi; Suzuki, Kota; Omura, Junichi; Shimizu, Toru; Fukumoto, Yoshihiro; Sakata, Yasuhiko; Shimokawa, Hiroaki 分享 收藏 Basigin Mediates Pulmonary Hypertension by Promoting Inflammation and Vascular Smooth Muscle Cell ProliferationSatoh, Kimio; Satoh, Taijyu; Kikuchi, Nobuhiro; Omura, Junichi; Kurosawa, Ryo; Suzuki, Kota; Sugimura, Koichiro; Aoki, Tatsuo; Nochioka, Kotaro; Tatebe, Shunsuke; Miyamichi-Yamamoto, Saori; Miura, Masanobu; Shimizu, Toru; Ikeda, Shohei; Yaoita, Nobuhiro; Fukumoto, Yoshihiro; Minami, Tatsuro; Miyata, Satoshi; Nakamura, Kazufumi; Ito, Hiroshi; Kadomatsu, Kenji; Shimokawa, Hiroaki 分享 收藏 Crucial Role of Rho-Kinase in Pressure Overload-Induced Right Ventricular Hypertrophy and Dysfunction in MiceIkeda, Shohei; Satoh, Kimio; Kikuchi, Nobuhiro; Miyata, Satoshi; Suzuki, Kota; Omura, Junichi; Shimizu, Toru; Kobayashi, Kenta; Kobayashi, Kazuto; Fukumoto, Yoshihiro; Sakata, Yasuhiko; Shimokawa, Hiroaki 分享 收藏 
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