Daniel P. Raleigh - Publications, H-index & Citations

Daniel P. Raleigh

Stony Brook University

72H指数

341论文数

1.6W被引数

收录论文 98

发表时间

Trimethylammonium-diphenylhexatriene and propionic acid-diphenylhexatriene are sensitive fluorescence probes of amyloid formation by human IAPP 三甲基铵二苯基己三烯和丙酸二苯基己三烯是人IAPP（人胰岛淀粉样多肽）淀粉样纤维形成的敏感荧光探针。

Analytical Biochemistry

IF2.5

2026-03-04

PREAI

Kyung-Hoon Lee; Lakshan Manathunga; Ming-Hao Li; Erwin London; Daniel P. Raleigh

Modulation of islet amyloid polypeptide induced β-cell toxicity and amyloid formation by serum albumin proteins 血清白蛋白蛋白对胰岛淀粉样多肽诱导的β细胞毒性及淀粉样蛋白形成的调节

Biophysical Chemistry

IF2.2

2025-12-13

PREAI

Alexander Zhyvoloup; Zachary Ridgway; Ananya Prashanth; Daniel P. Raleigh

Experimental and computational analysis of the basis for accelerated amyloid formation by a disease linked mutant of human islet amyloid polypeptide 实验与计算分析：由与人胰岛淀粉样多肽相关的疾病相关突变体加速淀粉样蛋白形成的机制

Protein Science

IF5.2

2025-10-30

PREAI

Lakshan Manathunga; Rehana Akter; Junjie Zou; Carlos Simmerling; Daniel P. Raleigh

The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity 胰岛组织纤溶酶原激活物/纤溶酶系统被人胰岛淀粉样多肽聚集上调，并保护 β 细胞免受聚集诱导的毒性

DIABETOLOGIA

IF10.2

2024-09-09

OAAI

Esser, Nathalie; Hogan, Meghan F.; Templin, Andrew T.; Akter, Rehana; Fountaine, Brendy S.; Castillo, Joseph J.; El-Osta, Assam; Manathunga, Lakshan; Zhyvoloup, Alexander; Raleigh, Daniel P.; Zraika, Sakeneh; Hull, Rebecca L.; Kahn, Steven E.

Understanding the structural dynamics of human islet amyloid polypeptide: Advancements in and applications of ion-mobility mass spectrometry 了解人类胰岛淀粉样多肽的结构动力学: 离子迁移质谱的进展和应用

BIOPHYSICAL CHEMISTRY

IF2.2

2024-09-01

OAAI

Dai, Zijie; Ben-Younis, Aisha; Vlachaki, Anna; Raleigh, Daniel; Thalassinos, Konstantinos

The processing intermediate of human amylin, pro-amylin(1-48), has in vivo and in vitro bioactivity

BIOPHYSICAL CHEMISTRY

IF2.2

2024-05-01

OAAI

Mazzini, Giulia; Le Foll, Christelle; Boyle, Christina N.; Garelja, Michael L.; Zhyvoloup, Alexander; Miller, Matthew E. T.; Hay, Debbie L.; Raleigh, Daniel P.; Lutz, Thomas A.

On the importance of being amidated: Analysis of the role of the conserved C-terminal amide of amylin in amyloid formation and cytotoxicity

BIOPHYSICAL CHEMISTRY

IF2.2

2024-04-01

OAAI

Yang, Tangweina; Filippov, Ivan; Manathunga, Lakshan; Baghai, Aria; Marechal, Amandine; Raleigh, Daniel P.; Zhyvoloup, Alexander

Interspecies Variation Affects Islet Amyloid Polypeptide Membrane Binding

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

IF2.7

2023-04-26

OAAI

Sanders, Henry M.; Chalyavi, Farzaneh; Fields, Caitlyn R.; Kostelic, Marius M.; Li, Ming-Hao; Raleigh, Daniel P.; Zanni, Martin T.; Marty, Michael T.

Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice 胰岛淀粉样多肽聚集对小鼠胰岛血管系统具有细胞毒性和促炎作用

DIABETOLOGIA

IF10.2

2022-07-25

OAAI

Castillo, Joseph J.; Aplin, Alfred C.; Hackney, Daryl J.; Hogan, Meghan F.; Esser, Nathalie; Templin, Andrew T.; Akter, Rehana; Kahn, Steven E.; Raleigh, Daniel P.; Zraika, Sakeneh; Hull, Rebecca L.

Preparation of Asymmetric Vesicles with Trapped CsCl Avoids Osmotic Imbalance, Non-Physiological External Solutions, and Minimizes Leakage

LANGMUIR

IF3.9

2021-09-22

OAAI

Li, Ming-Hao; Raleigh, Daniel P.; London, Erwin

Protein unfolded states populated at high and ambient pressure are similarly compact

BIOPHYSICAL JOURNAL

IF3.1

2021-06-01

OAAI

Harish, Balasubramanian; Gillilan, Richard E.; Zou, Junjie; Wang, Jinqiu; Raleigh, Daniel P.; Royer, Catherine A.

Scaffold Hopping Transformations Using Auxiliary Restraints for Calculating Accurate Relative Binding Free Energies

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2021-05-24

OAAI

Zou, Junjie; Li, Zhipeng; Liu, Shuai; Peng, Chunwang; Fang, Dong; Wan, Xiao; Lin, Zhixiong; Lee, Tai-Sung; Raleigh, Daniel P.; Yang, Mingjun; Simmerling, Carlos

Cyclic Ion Mobility-Collision Activation Experiments Elucidate Protein Behavior in the Gas Phase 循环离子迁移碰撞活化实验阐明了气相中的蛋白质行为

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

IF2.7

2021-05-18

OAAI

Eldrid, Charles; Ben-Younis, Aisha; Ujma, Jakub; Britt, Hannah; Cragnolini, Tristan; Kalfas, Symeon; Cooper-Shepherd, Dale; Tomczyk, Nick; Giles, Kevin; Morris, Mike; Akter, Rehana; Raleigh, Daniel; Thalassinos, Konstantinos

Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro

DIABETOLOGIA

IF10.2

2020-07-29

OAAI

Templin, Andrew T.; Mellati, Mahnaz; Meier, Daniel T.; Esser, Nathalie; Hogan, Meghan F.; Castillo, Joseph J.; Akter, Rehana; Raleigh, Daniel P.; Zraika, Sakeneh; Hull, Rebecca L.; Kahn, Steven E.

Plasmin-Mediated Cleavage of Human Islet Amyloid Polypeptide (hIAPP) Protects β-Cells from Amyloid-Induced Toxicity

DIABETES

IF7.5

2020-06-01

PREAI

Esser, Nathalie; Hogan, Meghan F.; Templin, Andrew T.; Castillo, Joseph J.; Raleigh, Daniel; Edgar, John S.; Zraika, Sakeneh; Hull, Rebecca L.; Kahn, Steven E.

Analysis of Amylin Consensus Sequences Suggests That Human Amylin Is Not Optimized to Minimize Amyloid Formation and Provides Clues to Factors That Modulate Amyloidogenicity

ACS CHEMICAL BIOLOGY

IF3.8

2020-05-04

OAAI

Noh, Daeun; Bower, Rebekah L.; Hay, Debbie L.; Zhyvoloup, Alexander; Raleigh, Daniel P.

Analysis of Baboon IAPP Provides Insight into Amyloidogenicity and Cytotoxicity of Human IAPP

BIOPHYSICAL JOURNAL

IF3.1

2020-03-01

OAAI

Ridgway, Zachary; Lee, Kyung-Hoon; Zhyvoloup, Alexander; Wong, Amy; Eldrid, Charles; Hannaberry, Eleni; Thalassinos, Konstantinos; Abedini, Andisheh; Raleigh, Daniel P.

Unfolded states under folding conditions accommodate sequence-specific conformational preferences with random coil-like dimensions 折叠条件下的未折叠状态适应具有随机线圈状尺寸的序列特异性构象偏好

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-06-05

OAAI

Peran, Ivan; Holehouse, Alex S.; Carrico, Isaac S.; Pappu, Rohit V.; Bilsel, Osman; Raleigh, Daniel P.

The Tissue Plasminogen Activator (tPA)/Plasmin System Reduces Amyloid Formation by Cleaving Human Islet Amyloid Polypeptide (hIAPP)

DIABETES

IF7.5

2019-06-01

PREAI

Esser, Nathalie; Hogan, Meghan F.; Aplin, Alfred; Templin, Andrew T.; El-Osta, Sam; Raleigh, Daniel; Edgar, John S.; Zraika, Sakeneh; Hull, Rebecca L.; Kahn, Steven E.

Pressure-Temperature Analysis of the Stability of the CTL9 Domain Reveals Hidden Intermediates

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Zhang, Siwen; Zhang, Yi; Stenzoski, Natalie E.; Zou, Junjie; Peran, Ivan; McCallum, Scott A.; Raleigh, Daniel P.; Royer, Catherine A.

研究方向