Alexander J. Mentzer - Publications, H-index & Citations

Alexander J. Mentzer

University of Oxford

76H指数

329论文数

3.5W被引数

收录论文 88

发表时间

Unveiling structural determinants of peptide recognition by public and private SARS-CoV-2-specific T-cell receptors 揭示公共和私有SARS-CoV-2特异性T细胞受体识别肽段的结构决定因素

Nature Communications

IF15.7

2026-09-22

OAAI

Caner Akıl; Yanchun Peng; Julia McCarthy; Yanan Zhu; Nathan Hardenbrook; Yunkai Yang; Danning Dong; Elie Antoun; Xuan Yao; Guihai Liu; Ji-li Chen; Esra Balıkçı; Raul Cioaca; Alexander J. Mentzer; Julian C. Knight; Ricardo A. Fernandes; Tao Dong; Peijun Zhang

Helicobacter pylori, herpes simplex virus-1, varicella-zoster virus, and dementia risk 幽门螺杆菌、单纯疱疹病毒-1、带状疱疹病毒与痴呆风险

Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

IF4.4

2026-08-17

OAAI

Thomas J. Littlejohns; Wenyu Liu; Carol Brayne; Julia Butt; Jennifer A. Collister; Nita G. Forouhi; Effrossyni Gkrania-Klotsas; Shabina Hayat; Katie Jeffery; Elżbieta Kuźma; Robert N. Luben; Alexander J. Mentzer; Julie Parsonnet; Nicholas Wareham; Tim Waterboer; David J. Hunter

A scalable high-throughput serolomics platform for profiling serum antibody responses in large-scale population-based cohorts 一种可扩展的高通量血清组学平台，用于大规模人群队列血清抗体反应的表征

Nature Protocols

IF16

2026-07-06

PREAI

Lea Kröller; Rima Jeske; Birgitta Michels; Julia Butt; Iona Millwood; Christiana Kartsonaki; Zhengming Chen; Jun Lv; Liming Li; Rasmus Gustafsson; Andrew Gordon; Frederik Romer; Hannah Fry; Sarah Clark; Michael Hill; Ling Yang; Alexander Mentzer; Tim Waterboer

Signatures of pathogen-driven selection and Austronesian gene flow of Papua New Guinea HLA alleles 新几内亚高地人类白细胞抗原等位基因中病原体驱动的选择和南岛语系基因流动的印记

The American Journal of Human Genetics

IF0

2026-05-04

OAAI

Neus Font-Porterias; Neda Nemat-Gorgani; Katherine M. Kichula; Dana R. Al-Hindi; Genelle F. Harrison; Sudan Tao; Faming Zhu; Gonzalo Montero-Martin; Marcelo A. Fernández-Viña; Lisbeth A. Guethlein; Peter Parham; Stephen J. Oppenheimer; Alexander G. Ioannidis; Andrés Moreno-Estrada; William Pomat; Alexander J. Mentzer; Brenna M. Henn; Paul J. Norman

African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children 非洲特异性的遗传位点决定非洲儿童中铁状况以及重症疟疾和菌血症的风险。

Nature Communications

IF15.7

2026-04-07

OAAI

John Muthii Muriuki; Alexander J. Mentzer; Gavin Band; Amanda Y. Chong; Alex W. Macharia; Reagan M. Mogire; Kelvin Mokaya Abuga; Ruth Mitchell; James J. Gilchrist; Emily L. Webb; Francis M. Ndungu; Laura M. Raffield; Lynette Ekunwe; Amy R. Bentley; Sodiomon B. Sirima; Shabir A. Madhi; Adrian V. S. Hill; Andrew M. Prentice; Philip Bejon; Gibran Hemani; George Davey Smith; Manjinder S. Sandhu; Alison M. Elliott; Thomas N. Williams; Adebowale Adeyemo; Sarah H. Atkinson

Context-specific regulatory genetic variation in MTOR dampens neutrophil-T cell crosstalk in pneumonia-associated sepsis MTOR中与特定环境相关的调控性遗传变异会削弱肺炎相关败血症中的中性粒细胞-淋巴细胞相互作用

Nature Communications

IF15.7

2026-02-25

OAAI

Ping Zhang; Patrick MacLean; Alicia Jia; Callum R. O’Neill; Alice Allcock; Ethan Prince; Bora Ozcan; Roman M. Doll; Imogen Dyne; Kiki Cano-Gamez; Hanyu Qin; Chloe Wainwright; Giuseppe Scozzafava; Andrew C. Brown; James O. J. Davies; Amanda Y. Chong; Alexander J. Mentzer; Katie L. Burnham; Emma E. Davenport; Julian C. Knight

Pediatric critical illness endotypes reveal distinct outcomes and immune pathways shared across cause of illness 儿科危重症内表型揭示了不同疾病原因下共享的不同结局和免疫通路

iScience

IF4.1

2025-11-26

OAAI

Michael J. Carter; Joshua Hageman; Yael Feinstein; Jethro Herberg; Dominic Habgood-Coote; Victoria Wright; Samuel Nichols; Nazima Pathan; Naomi Edmonds; Philip D. Cowie; Katie Burnham; Alexander Mentzer; Julian Knight; Michael Levin; Myrsini Kaforou; Simon Nadel; Mark J. Peters; Padmanabhan Ramnarayan

Time to tackle vaccine–HLA associations with artificial intelligence 是时候利用人工智能来解决疫苗–HLA关联问题了。

The Lancet Infectious Diseases

IF31

2025-11-17

PREAI

Alexander J Mentzer; George Davey Smith; Teresa Lambe; Julian C Knight; Mary Carrington

Acyclic graphs to define models of relationships between human cytomegalovirus, cardiovascular disease and all-cause mortality in UK Biobank 使用无环图定义英国生物银行中人类巨细胞病毒、心血管疾病和全因死亡率之间关系模型

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2025-11-06

PREAI

Doorly, Robert; Chong, Amanda Y.; Hamilton, Elizabeth; Littlejohns, Thomas J.; Knight, Julian C.; Kadambari, Seilesh; Klenerman, Paul; Mentzer, Alexander J.

Genetic association studies in critically ill patients: a systematic review 危重患者中的遗传关联研究：系统综述

EBIOMEDICINE

IF10.8

2025-04-01

OAAI

Zhang, Wenbo; Nguyen-Hoang, Nam; Rivrud, Sean C. S.; Zandbergen, Anne-Fleur; Yan, Yalan; Cox, Eline G. M.; Suarez-Pajes, Eva; Chong, Amanda Y.; Mentzer, Alexander J.; Flores, Carlos; Lunter, Gerton; Keus, Frederik; Snieder, Harold

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

HUMAN GENETICS AND GENOMICS ADVANCES

IF3.6

2024-11-01

OAAI

Karp-Tatham, Eleanor; O'Neill, R.; Knight, Julian C.; Mentzer, Alexander J.; Chong, Amanda Y.

Genetic Signatures of Positive Selection in Human Populations Adapted to High Altitude in Papua New Guinea

GENOME BIOLOGY AND EVOLUTION

IF2.8

2024-08-22

OAAI

Gonzalez-Buenfil, Ram; Vieyra-Sanchez, Sofia; Quinto-Cortes, Consuelo D.; Oppenheimer, Stephen J.; Pomat, William; Laman, Moses; Cervantes-Hernandez, Mayte C.; Barberena-Jonas, Carmina; Auckland, Kathryn; Allen, Angela; Allen, Stephen; Phipps, Maude E.; Huerta-Sanchez, Emilia; Ioannidis, Alexander G.; Mentzer, Alexander J.; Moreno-Estrada, Andres

High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response 高分辨率非洲HLA资源揭示了疫苗反应背后的HLA-DRB1表达效应

NATURE MEDICINE

IF50

2024-05-13

OAAI

Mentzer, Alexander J.; Dilthey, Alexander T.; Pollard, Martin; Gurdasani, Deepti; Karakoc, Emre; Carstensen, Tommy; Muhwezi, Allan; Cutland, Clare; Diarra, Amidou; Antunes, Ricardo da Silva; Paul, Sinu; Smits, Gaby; Wareing, Susan; Kim, Hwaran; Pomilla, Cristina; Chong, Amanda Y.; Brandt, Debora Y. C.; Nielsen, Rasmus; Neaves, Samuel; Timpson, Nicolas; Crinklaw, Austin; Arlehamn, Cecilia S. Lindestam; Rautanen, Anna; Kizito, Dennison; Parks, Tom; Auckland, Kathryn; Elliott, Kate E.; Mills, Tara; Ewer, Katie; Edwards, Nick; Fatumo, Segun; Webb, Emily; Peacock, Sarah; Jeffery, Katie; van der Klis, Fiona R. M.; Kaleebu, Pontiano; Vijayanand, Pandurangan; Peters, Bjorn; Sette, Alessandro; Cereb, Nezih; Sirima, Sodiomon; Madhi, Shabir A.; Elliott, Alison M.; Mcvean, Gil; Hill, Adrian V. S.; Sandhu, Manjinder S.

A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity

CELL REPORTS MEDICINE

IF10.6

2024-05-01

OAAI

Liu, Chang; Zhou, Daming; Dijokaite-Guraliuc, Aiste; Supasa, Piyada; Duyvesteyn, Helen M. E.; Ginn, Helen M.; Selvaraj, Muneeswaran; Mentzer, Alexander J.; Das, Raksha; de Silva, Thushan I.; Ritter, Thomas G.; Plowright, Megan; Newman, Thomas A. H.; Stafford, Lizzie; Kronsteiner, Barbara; Temperton, Nigel; Lui, Yuan; Fellermeyer, Martin; Goulder, Philip; Klenerman, Paul; Dunachie, Susanna J.; Barton, Michael I.; Kutuzov, Mikhail A.; Dushek, Omer; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

How could our genetics impact COVID-19 vaccine response?

EXPERT REVIEW OF CLINICAL IMMUNOLOGY

IF3.7

2024-04-27

PREAI

Zheng, Keyi; Chong, Amanda Y.; Mentzer, Alexander J.

Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection

NATURE COMMUNICATIONS

IF15.7

2024-04-16

OAAI

Liu, Chang; Das, Raksha; Dijokaite-Guraliuc, Aiste; Zhou, Daming; Mentzer, Alexander J.; Supasa, Piyada; Selvaraj, Muneeswaran; Duyvesteyn, Helen M. E.; Ritter, Thomas G.; Temperton, Nigel; Klenerman, Paul; Dunachie, Susanna J.; Paterson, Neil G.; Williams, Mark A.; Hall, David R.; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

Advancing Toxoplasma gondii multiplex serology 推进弓形虫多重血清学

MICROBIOLOGY SPECTRUM

IF3.8

2024-04-02

OAAI

Jeske, Rima; Becker, Nico; Kroeller, Lea; Mentzer, Alexander J.; Brenner, Nicole; Guy, Edward; Waterboer, Tim; Butt, Julia

The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86

NATURE COMMUNICATIONS

IF15.7

2024-03-28

OAAI

Zhou, Daming; Supasa, Piyada; Liu, Chang; Dijokaite-Guraliuc, Aiste; Duyvesteyn, Helen M. E.; Selvaraj, Muneeswaran; Mentzer, Alexander J.; Das, Raksha; Dejnirattisai, Wanwisa; Temperton, Nigel; Klenerman, Paul; Dunachie, Susanna J.; Fry, Elizabeth E.; Mongkolsapaya, Juthathip; Ren, Jingshan; Stuart, David I.; Screaton, Gavin R.

Genetic Susceptibility to Astrovirus Diarrhea in Bangladeshi Infants

OPEN FORUM INFECTIOUS DISEASES

IF3.8

2024-03-06

OAAI

Chen, Laura; Munday, Rebecca M.; Haque, Rashidul; Duchen, Dylan; Nayak, Uma; Korpe, Poonum; Mentzer, Alexander J.; Kirkpatrick, Beth D.; Wojcik, Genevieve L.; Petri Jr, William A.; Duggal, Priya

A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy 在英国生物库中通过抗体分析检测到的常见NFKB1变体可预测感染和过敏的风险

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-02-01

OAAI

Chong, Amanda Y.; Brenner, Nicole; Jimenez-Kaufmann, Andres; Cortes, Adrian; Hill, Michael; Littlejohns, Thomas J.; Gilchrist, James J.; Fairfax, Benjamin P.; Knight, Julian C.; Hodel, Flavia; Fellay, Jacques; Mcvean, Gil; Moreno-Estrada, Andres; Waterboer, Tim; Hill, Adrian V. S.; Mentzer, Alexander J.

研究方向