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Alexander H. Stegh

Ruprecht Karls University Heidelberg
H指数:32
被引数:7,435

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Recent progress and future directions to advance glioblastoma research: a consensus perspective from the 2024 Christopher Davidson Forum

胶质母细胞瘤研究进展与未来发展方向：2024年Christopher Davidson论坛共识观点

Neuro-Oncology
IF13.4
2026-04-010
PRE
Dunn, Gavin P.; Yu, Kenny K. H.; Krucoff, Max O.; Bojanowski-Hoang, Kimberly; Goldschmidt, Ezequiel; Erol-Demirturk, Mariye; Adesina, Daniel; Quintana, Daniel; Winkler, Frank; Hervey-Jumper, Shawn; Deneen, Benjamin; Giles, David A.; Ko, Caroline H.; Leuthardt, Eric C.; Kim, Albert H.; Stegh, Alexander H.
STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways

STING激活通过炎症性细胞死亡通路诱导脑膜瘤中的细胞毒性及免疫反应

Nature Communications
IF15.7
2026-02-120
OAAI
Mark W. Youngblood; Shashwat Tripathi; Hinda Najem; Harrshavasan Congivaram; Mateo Gomez; Thomas K. Sears; Lisa Hurley; Leah K. Billingham; Caylee Silvers; Wenxia Wang; Deanna Tiek; Nishanth Sadagopan; Rahul Chaliparambil; Qianyi Pu; Ching Man Wai; Abrar Choudhury; Alicia Steffens; Kathleen McCortney; Gustavo Ignacio Vazquez Cervantes; Daniel Oyon; Luis Fernandez; Ashley Selner; Jawad Fares; Matthew Hagan; S. Joy Trybula; Jacky Yeung; Matthieu Peyre; Michel Kalamarides; Peng Zhang; Alexander H. Stegh; David M. Ashley; Craig M. Horbinski; Jared T. Ahrendsen; Pouya Jamshidi; Daniel J. Brat; Rimas V. Lukas; Roger Stupp; Maciej S. Lesniak; Adam M. Sonabend; Gavin P. Dunn; James P. Chandler; Matthew C. Tate; Stephen T. Magill; Jason Miska; Michael A. Curran; David R. Raleigh; Amy B. Heimberger
Synergistic STING activation in meningioma neoplastic and immune populations triggers programmed necrosis and modulates the collagen-rich immunosuppressive microenvironment

在脑膜瘤的肿瘤和免疫细胞群体中，协同的STING激活会触发程序性坏死并调节富含胶原的免疫抑制性微环境。

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Youngblood, Mark; Tripathi, Shashwat; Najem, Hinda; Congivaram, Harrshavasan; Gomez, Mateo; Sears, Thomas; Hurley, Lisa; Billingham, Leah; Silvers, Caylee; Wang, Wenxia; Tiek, Deanna; Sadagopan, Nishanth; Chaliparambil, Rahul; Pu, Qianyi; Wai, Ching Man; Choudhury, Abrar; Steffens, Alicia; Mccortney, Kathleen; Cervantes, Gustavo; Oyon, Daniel; Fernandez, Luis; Selner, Ashley; Fares, Jawad; Hagan, Matthew; Trybula, Joy; Yeung, Jacky; Peyre, Matthieu; Kalamarides, Michel; Zhang, Peng; Stegh, Alexander; Ashley, David; Horbinski, Craig; Ahrendsen, Jared; Jamshidi, Pouya; Brat, Daniel; Lukas, Rimas; Stupp, Roger; Lesniak, Maciej; Sonabend, Adam; Dunn, Gavin; Chandler, James; Tate, Matthew; Magill, Stephen; Miska, Jason; Curran, Michael; Raleigh, David; Heimberger, Amy
MYELOID-ASSOCIATED WILD-TYPE IDH1 PROMOTES IMMUNOSUPPRESSION IN GLIOBLASTOMA
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Dussold, Corey; Tripathi, Shashwat; Mahajan, Akanksha; Tommasini-Ghelfi, Serena; Hurley, Lisa; Jarvis, Rachel; Najem, Hinda; Chalastanis, Alexandra; Sooreshjani, Moloud; Du, Ruochen; Mccornack, Colin; Giles, David; Turunen, Jillyn; Billingham, Leah; Kim, Seunghyun; Broom, Wendy; Dadali-Abel, Tulin; Murnan, Kevin; Horbinski, Craig; Thorp, Edward; Kim, Albert; Li, Yang; Miska, Jason; Heimberger, Amy; Stegh, Alexander
THERAPEUTIC TARGETING OF STING IN MENINGIOMAS
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Youngblood, Mark; Tripathi, Shashwat; Najem, Hinda; Gomez, Mateo; Sadagopan, Nishanth; Sears, Thomas; Hurley, Lisa; Wang, Wenxia; Congivaram, Harrshavasan; Choudhury, Abrar; Steffens, Alicia; Oyon, Daniel; Fernandez, Luis; Selner, Ashley; Fares, Jawad; Hagan, Matthew; Palmer, Aaron; Karras, Constantine; Trybula, Joy; Zhang, Peng; Stegh, Alexander; Curran, Michael; Ashley, David; Magill, Stephen; Horbinski, Craig; Chandler, James; Lesniak, Maciej; Miska, Jason; Dunn, Gavin; Raleigh, David; Heimberger, Amy
A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-03-10195
OA
Kumthekar, Priya; Ko, Caroline H.; Paunesku, Tatjana; Dixit, Karan; Sonabend, Adam M.; Bloch, Orin; Tate, Matthew; Schwartz, Margaret; Zuckerman, Laura; Lezon, Ray; Lukas, Rimas, V; Jovanovic, Borko; McCortney, Kathleen; Colman, Howard; Chen, Si; Lai, Barry; Antipova, Olga; Deng, Junjing; Li, Luxi; Tommasini-Ghelfi, Serena; Hurley, Lisa A.; Unruh, Dusten; Sharma, Nitya, V; Kandpal, Manoj; Kouri, Fotini M.; Davuluri, Ramana, V; Brat, Daniel J.; Muzzio, Miguel; Glass, Mitchell; Vijayakumar, Vinod; Heidel, Jeremy; Giles, Francis J.; Adams, Ann K.; James, C. David; Woloschak, Gayle E.; Horbinski, Craig; Stegh, Alexander H.
IDH3α regulates one-carbon metabolism in glioblastoma
SCIENCE ADVANCES
IF12.5
2019-01-0459
OAAI
May, Jasmine L.; Kouri, Fotini M.; Hurley, Lisa A.; Liu, Juan; Tommasini-Ghelfi, Serena; Ji, Yanrong; Gao, Peng; Calvert, Andrea E.; Lee, Andrew; Chandel, Navdeep S.; Davuluri, Ramana V.; Horbinski, Craig M.; Locasale, Jason W.; Stegh, Alexander H.
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
CELL REPORTS
IF6.9
2017-05-01172
OAAI
Calvert, Andrea E.; Chalastanis, Alexandra; Wu, Yongfei; Hurley, Lisa A.; Kouri, Fotini M.; Bi, Yingtao; Kachman, Maureen; May, Jasmine L.; Bartom, Elizabeth; Hua, Youjia; Mishra, Rama K.; Schiltz, Gary E.; Dubrovskyi, Oleksii; Mazar, Andrew P.; Peter, Marcus E.; Zheng, Hongwu; James, C. David; Burant, Charles F.; Chandel, Navdeep S.; Davuluri, Ramana V.; Horbinski, Craig; Stegh, Alexander H.
Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2017-04-0359
OAAI
Sita, Timothy L.; Kouri, Fotini M.; Hurley, Lisa A.; Merkel, Timothy J.; Chalastanis, Alexandra; May, Jasmine L.; Ghelfi, Serena T.; Cole, Lisa E.; Cayton, Thomas C.; Barnaby, Stacey N.; Sprangers, Anthony J.; Savalia, Nikunjkumar; James, Charles David; Lee, Andrew; Mirkin, Chad A.; Stegh, Alexander H.

研究方向

暂未获取到该数据
L
Lisa Hurley
H 指数:19论文数:54被引数:3,032
F
Fotini M. Kouri
H 指数:18论文数:46被引数:2,517
C
Craig Horbinski
H 指数:84论文数:806被引数:2.4万
C
Chad A. Mirkin
H 指数:183论文数:1,692被引数:16.3万
A
Amy B. Heimberger
H 指数:88论文数:680被引数:3.0万
S
Serena Tommasini-Ghelfi
H 指数:5论文数:13被引数:590
M
Marcus E. Peter
H 指数:88论文数:326被引数:5.0万
C
C. David James
H 指数:101论文数:396被引数:3.8万
H
Hinda Najem
H 指数:15论文数:91被引数:679
J
Jason Miska
H 指数:31论文数:206被引数:4,546