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R

Ramón Hurtado‐Guerrero

University of Zaragoza

40H指数
221论文数
4.1K被引数
收录论文 104
发表时间
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Single-Atom O/S/Se Substitution at the Glycosidic Linkage in Glycopeptide Cancer Vaccines Reveals Divergent Performance糖肽癌症疫苗中糖苷键处的单原子O/S/Se取代揭示不同的性能
errAngewandte Chemie-International Edition
IF16.9
err2026-09-22
err0
PREAI
errCarmen Bretón; Ana Guerreiro; Paula Oroz; Noelia Osés; Irene Ginés-Alcober; Francisco Javier Cañada; Ramón Hurtado-Guerrero; Juan L. Asensio; Jesús M. Peregrina; Gonçalo J. L. Bernardes; Francisco Corzana
err分享
err收藏
Sulfonylurea Bioisosteres of Sulfonic Acid in JFD 00458-Based ST6GAL1 Inhibitors Enhance Membrane Permeability磺酸类取代的磺酰脲生物电子等排体在JFD 00458基ST6GAL1抑制剂中增强膜通透性
errChemMedChem
IF3.4
err2026-09-08
err0
errOAAI
errNatan Koraj; Sushmaa Dangudubiyyam; Adelyn M. Betances-Mora; Ema Faganeli; Anne Harduin-Lepers; Jesús Angulo; Tan Khanh Nguyen; María Bort-Griñó; Ramon Hurtado-Guerrero; Marko Anderluh
err分享
err收藏
Glycosyltransferases: Capturing catalytic states and conformational gating糖基转移酶：捕获催化状态和构象门控
errCurrent Opinion in Chemical Biology
IF6.1
err2026-08-28
err0
PREAI
errAlejandro Montesa; Alejandro Pérez-Latorre; Pedro Merino; Ramon Hurtado-Guerrero
err分享
err收藏
Variant-dependent pharmacological rescue of phenylalanine hydroxylase supports a precision therapeutic strategy for phenylketonuria变异体依赖性苯丙氨酸羟化酶的药理学拯救支持苯丙酮尿症的精准治疗策略
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-04-15
err0
errOAAI
errMaría Conde-Giménez; Sandra Salillas; María Galiana-Cameo; Juan E. Martínez-Oliván; Alejandro Mahía; Manuel Ledesma; Juan José Galano-Frutos; Ritwik Maity; Adrián Velázquez-Campoy; María D. Díaz-de-Villegas; Ramón Hurtado-Guerrero; Javier Sancho
err分享
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Discovery of a secreted Bacteroides fragilis mucinase that cleaves mucins with bis-T O-glycans through a carbohydrate binding module-dependent mechanism发现一种分泌型的脆弱拟杆菌（Bacteroides fragilis）黏蛋白酶，该酶通过碳水化合物结合模块依赖性机制裂解含双-T O-糖苷键的黏蛋白。
errGut Microbes
IF11
err2026-03-19
err0
errOAAI
errYoshiki Narimatsu; Cayetano Pleguezuelos-Manzano; Daniel Hornikx; Felix Goerdeler; Thapakorn Jaroentomeechai; Katia Flores; Sanae Narimatsu; Charelle Boot; Lars Hansen; Fabien Durbesson; Renaud Vincentelli; Laurie Comstock; Hans Clevers; Victor Taleb; Francisco Corzana; Bernard Henrissat; Henrik Clausen; Ramon Hurtado-Guerrero; Christian Büll
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err收藏
Plant fucosyltransferase FUT11 distorts the sugar acceptor to catalyze via a transient oxocarbenium intermediate mechanism植物岩藻糖基转移酶FUT11使糖受体扭曲以通过瞬时氧代碳酰中间体机制进行催化
errNature Communications
IF15.7
err2026-01-23
err0
errOAAI
errVíctor Taleb; Ignacio Sanz-Martínez; Sonia Serna; María Bort-Griñó; Yoshiki Narimatsu; Sanae Furukawa; Niels C. Reichardt; Henrik Clausen; Pedro Merino; Ramon Hurtado-Guerrero
err分享
err收藏
Mechanism of Bacterial Arginine N-Glycosylation: A Chemically Challenging Post-Translational Modification细菌精氨酸N-糖基化机制：一种化学上具有挑战性的翻译后修饰
errACS Catalysis
IF13.1
err2026-01-14
err0
errOAAI
errBeatriz Piniello; Ana García-García; Fabio Pietrucci; Ramón Hurtado-Guerrero; Carme Rovira
err分享
err收藏
Structure, function, and implications of fucosyltransferases in health and disease岩藻糖基转移酶的结构、功能及其在健康与疾病中的意义
errNature Communications
IF15.7
err2025-12-08
err0
errOAAI
errMattia Ghirardello; Inmaculada Yruela; Pedro Merino; Robert Sackstein; Ignacio Sanz-Martínez; Ramón Hurtado-Guerrero
err分享
err收藏
FUT8 Catalysis Involves GDP-Fucose-Induced Loop Activation Promoting a Reaction at the SN1-SN2 Frontier
errACS CATALYSIS
IF13.1
err2025-12-01
err0
PREAI
errSanz-Martinez, Ignacio; Tejero, Tomas; Hurtado-Guerrero, Ramon; Merino, Pedro
err分享
err收藏
Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins微生物结合模块采用复杂的聚集糖基斑片选择性地粘附于黏蛋白
errNature Communications
IF15.7
err2025-10-13
err0
errOAAI
errThapakorn Jaroentomeechai; Billy Veloz; Cátia O. Soares; Felix Goerdeler; Ana Sofia Grosso; Christian Büll; Rebecca L. Miller; Sanae Furukawa; Irene Ginés-Alcober; Víctor Taleb; Pedro Merino; Mattia Ghirardello; Ismael Compañón; Helena Coelho; Jorge S. Dias; Renaud Vincentelli; Bernard Henrissat; Hiren Joshi; Henrik Clausen; Francisco Corzana; Filipa Marcelo; Ramon Hurtado-Guerrero; Yoshiki Narimatsu
err分享
err收藏
Structure-guided phage display discovery of antibodies for (S)Tn-glycans in protein context基于结构的噬菌体展示法发现蛋白质背景下(S)Tn-糖链的抗体
errNature Chemical Biology
IF13.7
err2025-07-31
err0
PREAI
errRamon Hurtado-Guerrero; Spyridon Gatos; Irene Ginés-Alcober; Javier Macías-León; Andrés Manuel González-Ramírez; Ilknur Kasapoglu; Billy Veloz; Ismael Compañón; Mattia Ghirardello; Pedro Merino; Francisco Corzana; Ola Blixt
err分享
err收藏
FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation InhibitorsFUT8 是前列腺肿瘤生长的关键驱动因子，并且可以通过岩藻糖基化抑制剂进行靶向治疗。
errCANCER MEDICINE
IF3.1
err2025-05-19
err0
errOAAI
errBastian, Kayla; Orozco-Moreno, Margarita; Thomas, Huw; Hodgson, Kirsty; Visser, Eline A.; Rossing, Emiel; Pijnenborg, Johan F. A.; Eerden, Nienke; Wilson, Laura; Saravannan, Hasvini; Hanley, Oliver; Grimsley, Grace; Frame, Fiona; Peng, Ziqian; Knight, Bridget; Mccullagh, Paul; Mcgrath, John; Crundwell, Malcolm; Harries, Lorna; Maitland, Norman J.; Heer, Rakesh; Wang, Ning; Goddard-Borger, Ethan D.; Guerrero, Ramon Hurtado; Boltje, Thomas J.; Drake, Richard R.; Scott, Emma; Elliott, David J.; Munkley, Jennifer
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Charge matters: how flanking substrate charge modulates O-glycan Core elongation电荷很重要：侧翼底物电荷如何调控O-糖链核心延伸
errGLYCOBIOLOGY
IF3.3
err2025-03-10
err0
PREAI
errBallard, Collin J.; Smutny, Matthew R.; Chau, Lam D.; Wong, Collin K.; Aharoni, Haley M.; Lee, Hana K.; Chapla, Digantkumar G.; Hurtado-Guerrero, Ramon; Moremen, Kelley W.; Gerken, Thomas A.
err分享
err收藏
Mammalian cell-based production of glycans, glycopeptides and glycomodules基于哺乳动物细胞的聚糖，糖肽和糖模块的生产
errNATURE COMMUNICATIONS
IF15.7
err2024-11-08
err0
errOAAI
errJaroentomeechai, Thapakorn; Karlsson, Richard; Goerdeler, Felix; Teoh, Fallen Kai Yik; Gronset, Magnus Norregaard; de Wit, Dylan; Chen, Yen-Hsi; Furukawa, Sanae; Psomiadou, Venetia; Hurtado-Guerrero, Ramon; Vidal-Calvo, Elena Ethel; Salanti, Ali; Boltje, Thomas J.; van den Bos, Leendert J.; Wunder, Christian; Johannes, Ludger; Schjoldager, Katrine T.; Joshi, Hiren J.; Miller, Rebecca L.; Clausen, Henrik; Vakhrushev, Sergey Y.; Narimatsu, Yoshiki
err分享
err收藏
Development of a FUT8 Inhibitor with Cellular Inhibitory Properties
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-11-06
err1
errOAAI
errManabe, Yoshiyuki; Takebe, Tomoyuki; Kasahara, Satomi; Hizume, Koki; Kabayama, Kazuya; Kamada, Yoshihiro; Asakura, Akiko; Shinzaki, Shinichiro; Takamatsu, Shinji; Miyoshi, Eiji; Garcia-Garcia, Ana; Vakhrushev, Sergey Y.; Hurtado-Guerrero, Ramon; Fukase, Koichi
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err收藏
Rational Design of Dual-Domain Binding Inhibitors for N-Acetylgalactosamine Transferase 2 with Improved Selectivity over the T1 and T3 IsoformsN-乙酰半乳糖胺转移酶2双结构域结合抑制剂的合理设计，对T1和T3亚型具有更高的选择性
errJACS AU
IF8.7
err2024-09-11
err0
errOAAI
errCompanon, Ismael; Ballard, Collin J.; Lira-Navarrete, Erandi; Santos, Tanausu; Monaco, Serena; Munoz-Garcia, Juan C.; Delso, Ignacio; Angulo, Jesus; Gerken, Thomas A.; Schjoldager, Katrine T.; Clausen, Henrik; Tejero, Tomas; Merino, Pedro; Corzana, Francisco; Hurtado-Guerrero, Ramon; Ghirardello, Mattia
err分享
err收藏
Detection of Tumor-Associated Autoantibodies in the Sera of Pancreatic Cancer Patients Using Engineered MUC1 Glycopeptide Nanoparticle Probes
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-08-07
err0
errOAAI
errCorzana, Francisco; Asin, Alicia; Eguskiza, Ander; De Tomi, Elisa; Martin-Carnicero, Alfonso; Martinez-Moral, Maria P.; Mangini, Vincenzo; Papi, Francesco; Breton, Carmen; Oroz, Paula; Lagartera, Laura; Jimenez-Moreno, Ester; Avenoza, Alberto; Busto, Jesus H.; Nativi, Cristina; Asensio, Juan L.; Hurtado-Guerrero, Ramon; Peregrina, Jesus M.; Malerba, Giovanni; Martinez, Alfredo; Fiammengo, Roberto
err分享
err收藏
Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal β-1,3-Glucanosyltransferases
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-07-22
err0
errOAAI
errRedrado-Hernandez, Sergio; Macias-Leon, Javier; Castro-Lopez, Jorge; Sanz, Ana Belen; Dolader, Elena; Arias, Maykel; Gonzalez-Ramirez, Andres Manuel; Sanchez-Navarro, David; Petryk, Yuliya; Farkas, Vladimir; Vincke, Cecile; Muyldermans, Serge; Garcia-Barbazan, Irene; del Agua, Celia; Zaragoza, Oscar; Arroyo, Javier; Pardo, Julian; Galvez, Eva M.; Hurtado-Guerrero, Ramon
err分享
err收藏
Identification of FasL as a crucial host factor driving COVID-19 pathology and lethality
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2024-03-21
err3
errOAAI
errAlbert, Marie-Christine; Uranga-Murillo, Iratxe; Arias, Maykel; De Miguel, Diego; Pena, Natacha; Montinaro, Antonella; Varanda, Ana Beatriz; Theobald, Sebastian J.; Areso, Itziar; Saggau, Julia; Koch, Manuel; Liccardi, Gianmaria; Peltzer, Nieves; Rybniker, Jan; Hurtado-Guerrero, Ramon; Merino, Pedro; Monzon, Marta; Badiola, Juan J.; Reindl-Schwaighofer, Roman; Sanz-Pamplona, Rebeca; Cebollada-Solanas, Alberto; Megyesfalvi, Zsolt; Dome, Balazs; Secrier, Maria; Hartmann, Boris; Bergmann, Michael; Pardo, Julian; Walczak, Henning
err分享
err收藏
Synthesis and immunological evaluation of TLR1/2 ligand-conjugated RBDs as self-adjuvanting vaccine candidates against SARS-CoV-2TLR1/2配体结合的RBDs作为抗SARS-CoV-2自身辅助疫苗候选物的合成和免疫学评价
errCHEMICAL COMMUNICATIONS
IF4.2
err2024-01-01
err1
errOAAI
errManabe, Yoshiyuki; Garate-Reyes, Brandon; Ito, Keita; Hurtado-Guerrero, Ramon; Kabayama, Kazuya; Fukase, Koichi
err分享
err收藏

研究方向

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