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Dominance of mutations in epigenetic regulators and a diversity of signaling alterations in blast-phase BCR::ABL1-negative myeloproliferative neoplasms Gurban, Petruta; Mambet, Cristina; Botezatu, Anca; Necula, Laura G.; Matei, Lilia; Neagu, Ana Iulia; Pitica, Ioana; Ataman, Marius; Tatic, Aurelia; Bardas, Alexandru; Gaman, Mihnea A.; Dobrea, Camelia; Dragomir, Mihaela; Ghimici, Cecilia; Angelescu, Silvana; Barbu, Doina; Stanca, Oana; Danila, Marina; Berbec, Nicoleta; Colita, Andrei; Vladareanu, Ana Maria; Nedeianu, Saviana; Chivu-Economescu, Mihaela; Bleotu, Coralia; Coriu, Daniel; Sepulchre, Elise; Anton, Gabriela; Diaconu, Carmen C.; Constantinescu, Stefan N. 分享 收藏
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Leukemic conversion involving RAS mutations of type 1 CALR-mutated primary myelofibrosis in a patient treated for HCV cirrhosis: a case report Gurban, Petruta; Mambet, Cristina; Botezatu, Anca; Necula, Laura G.; Neagu, Ana I.; Matei, Lilia; Pitica, Ioana M.; Nedeianu, Saviana; Chivu-Economescu, Mihaela; Bleotu, Coralia; Ataman, Marius; Mocanu, Gabriela; Saguna, Carmen; Pavel, Anca G.; Stambouli, Danae; Sepulchre, Elise; Anton, Gabriela; Diaconu, Carmen C.; Constantinescu, Stefan N. 分享 收藏
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Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers Defour, Jean-Philippe; Leroy, Emilie; Dass, Sharmila; Balligand, Thomas; Levy, Gabriel; Brett, Ian C.; Papadopoulos, Nicolas; Mouton, Celine; Genet, Lidvine; Pecquet, Christian; Staerk, Judith; Smith, Steven O.; Constantinescu, Stefan N.; Kay, Lewis E. 分享 收藏
Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology 衰老相关的自噬损伤诱导淀粉样蛋白病理小鼠模型神经内 β 淀粉样蛋白的毒性积累 Suelves, Nuria; Saleki, Shirine; Ibrahim, Tasha; Palomares, Debora; Moonen, Sebastiaan; Koper, Marta J.; Vrancx, Celine; Vadukul, Devkee M.; Papadopoulos, Nicolas; Viceconte, Nikenza; Claude, Eloise; Vandenberghe, Rik; von Arnim, Christine A. F.; Constantinescu, Stefan N.; Thal, Dietmar Rudolf; Decottignies, Anabelle; Kienlen-Campard, Pascal 分享 收藏
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice Willekens, Christophe; Laplane, Lucie; Dagher, Tracy; Benlabiod, Camelia; Papadopoulos, Nicolas; Lacout, Catherine; Rameau, Philippe; Catelain, Cyril; Alfaro, Alexia; Edmond, Valerie; Signolle, Nicolas; Marchand, Valentine; Droin, Nathalie; Hoogenboezem, Remco; Schneider, Rebekka. K. K.; Penson, Alex; Abdel-Wahab, Omar; Giraudier, Stephane; Pasquier, Florence; Marty, Caroline; Plo, Isabelle; Villeval, Jean-Luc; Constantinescu, Stefan. N. N.; Porteu, Francoise; Vainchenker, William; Solary, Eric 分享 收藏
Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation Papadopoulos, Nicolas; Nedelec, Audrey; Derenne, Allison; Sulea, Teodor Asvadur; Pecquet, Christian; Chachoua, Ilyas; Vertenoeil, Gaelle; Tilmant, Thomas; Petrescu, Andrei-Jose; Mazzucchelli, Gabriel; Iorga, Bogdan I.; Vertommen, Didier; Constantinescu, Stefan N. 分享 收藏
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A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection 全球努力剖析抵抗SARS-CoV-2感染的人类遗传基础 Andreakos, Evangelos; Abel, Laurent; Vinh, Donald C.; Kaja, Elzbieta; Drolet, Beth A.; Zhang, Qian; O'Farrelly, Cliona; Novelli, Giuseppe; Rodriguez-Gallego, Carlos; Haerynck, Filomeen; Prando, Carolina; Pujol, Aurora; Su, Helen C.; Casanova, Jean-Laurent; Spaan, Andras N.; Bastard, Paul; Biggs, Catherine M.; Bigio, Benedetta; Boisson, Bertrand; Bolze, Alexandre; Bondarenko, Anastasiia; Brodin, Petter; Chakravorty, Samya; Christodoulou, John; Cobat, Aurelie; Condino-Neto, Antonio; Constantinescu, Stefan N.; Feldman, Hagit Baris; Fellay, Jacques; Halwani, Rabih; Jouanguy, Emmanuelle; Lau, Yu-Lung; Meyts, Isabelle; Mogensen, Trine H.; Okada, Satoshi; Okamoto, Keisuke; Ozcelik, Tayfun; Pan-Hammarstrom, Qiang; Planas, Anna M.; Puel, Anne; Quintana-Murci, Lluis; Renia, Laurent; Resnick, Igor; Sediva, Anna; Shcherbina, Anna; Slaby, Ondrej; Tancevski, Ivan; Turvey, Stuart E.; Uddin, K. M. Furkan; van de Beek, Diederik; Zatz, Mayana; Zawadzki, Pawel; Zhang, Shen-Ying 分享 收藏
Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms Secardin, Lise; Gomez Limia, Cintia; da Silva-Benedito, Suzana; Lordier, Larissa; El-Khoury, Mira; Marty, Caroline; Ianotto, Jean-Christophe; Raslova, Hana; Constantinescu, Stefan N.; Bonamino, Martin Hernan; Vainchenker, William; Monte-Mor, Barbara; Di Stefano, Antonio; Plo, Isabelle 分享 收藏
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A typical acute lymphoblastic leukemia JAK2 variant, R683G, causes an aggressive form of familial thrombocytosis when germline 典型的急性淋巴细胞白血病JAK2变体R683G在种系时会导致家族性血小板增多症的侵袭性形式 Carreno-Tarragona, Gonzalo; Varghese, Leila N.; Sebastian, Elena; Galvez, Eva; Marin-Sanchez, Alberto; Lopez-Munoz, Nieves; Nam-Cha, Syonghyun; Martinez-Lopez, Joaquin; Constantinescu, Stefan N.; Sevilla, Julian; Ayala, Rosa 分享 收藏
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