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Štefan Kaluz

Emory University

H指数:27

被引数:2,658

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Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1α C-terminal activation domain

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27113

OAAI

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1α in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2792

OAAI

Targeting HIF-activated collagen prolyl 4-hydroxylase expression disrupts collagen deposition and blocks primary and metastatic uveal melanoma growth

IF7.3

2021-07-0318

OAAI

EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway (vol 39, pg 1041, 2019)

IF7.3

2019-11-015

OAAI

EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway

IF7.3

2019-10-0335

OAAI

Arylsulfonamide KCN1 suppresses primary and metastatic growth of uveal melanoma through anti-angiogenic and anti-invasion mechanisms

CANCER RESEARCH

IF16.6

2019-07-010

PRE

Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma

CLINICAL CANCER RESEARCH

IF10.2

2019-04-0152

OAAI

Taking a HIF pill for old age diseases?

IF3.9

2018-03-015

OAAI

Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex

IF16.6

2014-02-01259

OAAI

Hypoxia inducible factor pathway inhibitors as anticancer therapeutics

FUTURE MEDICINAL CHEMISTRY

IF3.4

2013-04-10118

OA

Arylsulfonamide KCN1 Inhibits In Vivo Glioma Growth and Interferes with HIF Signaling by Disrupting HIF-1α Interaction with Cofactors p300/CBP

CLINICAL CANCER RESEARCH

IF10.2

2012-12-1679

OA

Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2012-07-0619

OAAI

A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1

前蛋白转化酶/MMP-14蛋白水解级联反应从肿瘤抑制因子BAI1释放新型40 kDa血管抑制素

IF7.3

2012-02-1370

OAAI

Design and Synthesis of Novel Small-Molecule Inhibitors of the Hypoxia Inducible Factor Pathway

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2011-11-2350

OA

Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase 1act/Tubulin Interaction Is an Important Determinant of Mitotic Stability in Cultured HT1080 Human Fibrosarcoma Cells

CANCER RESEARCH

IF16.6

2010-07-1418

OAAI

PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes, CA9 and VEGF, in human cancer cell lines

IF10.1

2009-09-0155

OAAI

Transcriptional control of the tumor- and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

IF8.3

2009-04-01218

OAAI

Regulation of gene expression by hypoxia:: Integration of the HIF-transduced hypoxic signal at the hypoxia-responsive element

低氧对基因表达的调控:: HIF转导的低氧信号在低氧响应元件上的整合

CLINICA CHIMICA ACTA

IF2.9

2008-09-01164

OAAI

Does inhibition of degradation of hypoxia-inducible factor (HIF) α always lead to activation of HIF?: Lessons learnt from the effect of proteasomal inhibition on HIF activity

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2007-12-0428

PREAI

The role of extracellular signal-regulated protein kinase in transcriptional regulation of the hypoxia marker carbonic anhydrase IX

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2005-01-0129

PREAI