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Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology (vol 223, e20251067, 2026) 单细胞和空间分析揭示结核分枝杆菌诱导的肌成纤维细胞是肺病病理的驱动因素 (vol 223, e20251067, 2026) Mbano, Ian M.; Liu, Nuo; Wadsworth II, Marc H.; Chambers, Mark J.; Mpotje, Thabo; Asowata, Osaretin E.; Nyquist, Sarah K.; Nargan, Kievershen; Ramsuran, Duran; Karim, Farina; Hughes, Travis K.; Bromley, Joshua D.; Krause, Robert; Naidoo, Threnesan; Tezera, Liku B.; Reichmann, Michaela T.; Ganchua, Sharie Keanne; Kloverpris, Henrik N.; Dullabh, Kaylesh J.; Madansein, Rajhmun; Triana, Sergio; Steyn, Adrie J. C.; Berger, Bonnie; Marakalala, Mohlopheni J.; Pollara, Gabriele; Fortune, Sarah M.; Flynn, Joanne L.; Elkington, Paul T.; Shalek, Alex K.; Leslie, Alasdair 分享 收藏
Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology 单细胞和空间分析揭示结核分枝杆菌诱导的肌成纤维细胞是肺病理学的驱动因素 Mbano, Ian M.; Liu, Nuo; Wadsworth II, Marc H.; Chambers, Mark J.; Mpotje, Thabo; Asowata, Osaretin E.; Nyquist, Sarah K.; Nargan, Kievershen; Ramsuran, Duran; Karim, Farina; Hughes, Travis K.; Bromley, Joshua D.; Krause, Robert; Naidoo, Threnesan; Tezera, Liku B.; Reichmann, Michaela T.; Ganchua, Sharie Keanne; Kloverpris, Henrik N.; Dullabh, Kaylesh J.; Madansein, Rajhmun; Triana, Sergio; Steyn, Adrie J. C.; Berger, Bonnie; Marakalala, Mohlopheni J.; Fortune, Sarah M.; Flynn, JoAnne L.; Elkington, Paul T.; Shalek, Alex K.; Leslie, Alasdair 分享 收藏
Single-cell profiling reveals a role for tuberculosis-induced myofibroblasts in the immunopathology of infected lungs Liu, Nuo; Mbano, Ian Maheti; Wardsworth, Marc; Chambers, Mark; Mpotje, Thabo; Asowata, Osaretin; Nyquist, Sarah; Nargan, Kievershen; Ramsuran, Duran; Karim, Farina; Hughes, Travis; Bromley, Joshua; Krause, Robert; Tezera, Liku; Reichmann, Michaela; Keanne, Sharie; Ganchua, C.; Kloverpris, Henrik; Dullabh, Kaylesh; Madansein, Rajhmun; Triana, Sergio; Steyn, Adrie; Berger, Bonnie; Marakalala, Mohlopheni; Fortune, Sarah; Flynn, Joanne L.; Elkington, Paul T.; Shalek, Alex K.; Leslie, Alasdair 分享 收藏
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CD4+ T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection (vol 57, pg 2380, 2024) CD4+ T细胞通过重塑肉芽肿细胞构成和调控网络，在结核分枝杆菌再感染后促进免疫调节（卷57，页2380，2024） Bromley, Joshua D.; Ganchua, Sharie Keanne C.; Nyquist, Sarah K.; Maiello, Pauline; Borish, H. Jacob; Rodgers, Mark; Tomko, Jaime; Kracinovsky, Kara; Mugahid, Douaa; Nguyen, Son; Wang, Qianchang Dennis; Rosenberg, Jacob M.; Klein, Edwin C.; Gideon, Hannah P.; Floyd-O'Sullivan, Roisin; Berger, Bonnie; Scanga, Charles A.; Lin, Philana Ling; Fortune, Sarah M.; Shalek, Alex K.; Flynn, JoAnne L. 分享 收藏
High-dose intravenous BCG vaccination induces enhanced immune signaling in the airways 高剂量静脉BCG疫苗接种诱导气道中增强的免疫信号传导 Peters, Joshua M.; Irvine, Edward B.; Makatsa, Mohau S.; Rosenberg, Jacob M.; Wadsworth II, Marc H.; Hughes, Travis K.; Sutton, Matthew S.; Nyquist, Sarah K.; Bromley, Joshua D.; Mondal, Rajib; Seder, Robert A.; Darrah, Patricia A.; Seshadri, Chetan; Flynn, JoAnne L.; Shalek, Alex K.; Fortune, Sarah M. 分享 收藏
CD4+T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection Bromley, Joshua D.; Ganchua, Sharie Keanne C.; Nyquist, Sarah K.; Maiello, Pauline; Chao, Michael; Borish, H. Jacob; Rodgers, Mark; Tomko, Jaime; Kracinovsky, Kara; Mugahid, Douaa; Nguyen, Son; Wang, Qianchang Dennis; Rosenberg, Jacob M.; Klein, Edwin C.; Gideon, Hannah P.; Floyd-O'Sullivan, Roisin; Berger, Bonnie; Scanga, Charles A.; Lin, Philana Ling; Fortune, Sarah M.; Shalek, Alex K.; Flynn, JoAnne L. 分享 收藏
CD8+ lymphocytes are critical for early control of tuberculosis in macaques CD8淋巴细胞对猕猴结核病的早期控制至关重要 Winchell, Caylin G.; Nyquist, Sarah K.; Chao, Michael C.; Maiello, Pauline; Myers, Amy J.; Hopkins, Forrest; Chase, Michael; Gideon, Hannah P.; Patel, Kush V.; Bromley, Joshua D.; Simonson, Andrew W.; Floyd-O'Sullivan, Roisin; Wadsworth, Marc; Rosenberg, Jacob M.; Uddin, Rockib; Hughes, Travis; Kelly, Ryan J.; Griffo, Josephine; Tomko, Jaime; Klein, Edwin; Berger, Bonnie; Scanga, Charles A.; Mattila, Joshua; Fortune, Sarah M.; Shalek, Alex K.; Lin, Philana Ling; Flynn, JoAnne L. 分享 收藏
HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control Fardoos, Rabiah; Nyquist, Sarah K.; Asowata, Osaretin E.; Kazer, Samuel W.; Singh, Alveera; Ngoepe, Abigail; Giandhari, Jennifer; Mthabela, Ntombifuthi; Ramjit, Dirhona; Singh, Samita; Karim, Farina; Buus, Soren; Anderson, Frank; Porterfield, J. Zachary; Sibiya, Andile L.; Bipath, Rishan; Moodley, Kumeshan; Kuhn, Warren; Berger, Bonnie; Nguyen, Son; de Oliveira, Tulio; Ndung'u, Thumbi; Goulder, Philip; Shalek, Alex K.; Leslie, Alasdair; Kloverpris, Henrik N. 分享 收藏
Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis) Jaiswal, Swati; Nyquist, Sarah K.; Boyce, Shayla; Jivanjee, Tasneem; Ibrahim, Samira; Bromley, Joshua D.; Gatter, G. James; Gideon, Hannah; Patel, Kush; Ganchua, Sharie Keanne; Berger, Bonnie; Fortune, Sarah M.; Flynn, JoAnne L.; Shalek, Alex K.; Behar, Samuel M. 分享 收藏
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control 猕猴肺部肉芽肿的多模式分析揭示了结核病控制的细胞相关性 Gideon, Hannah P.; Hughes, Travis K.; Tzouanas, Constantine N.; Wadsworth, Marc H., II; Tu, Ang Andy; Gierahn, Todd M.; Peters, Joshua M.; Hopkins, Forrest F.; Wei, Jun-Rong; Kummerlowe, Conner; Nargan, Kievershen; Phuah, Jia Yao; Borish, H. Jacob; Maiello, Pauline; White, Alexander G.; Winchell, Caylin G.; Nyquist, Sarah K.; Ganchua, Sharie Keanne C.; Myers, Amy; V. Patel, Kush; Ameel, Cassaundra L.; Cochran, Catherine T.; Ibrahim, Samira; Tomko, Jaime A.; Frye, Lonnie James; Rosenberg, Jacob M.; Shih, Angela; Chao, Michael; Klein, Edwin; Scanga, Charles A.; Ordovas-Montanes, Jose; Berger, Bonnie; Mattila, Joshua T.; Madansein, Rajhmun; Love, J. Christopher; Lin, Philana Ling; Leslie, Alasdair; Behar, Samuel M.; Bryson, Bryan; Flynn, JoAnne L.; Fortune, Sarah M.; Shalek, Alex K. 分享 收藏
Cellular and transcriptional diversity over the course of human lactation Nyquist, Sarah K.; Gao, Patricia; Haining, Tessa K. J.; Retchin, Michael R.; Golan, Yarden; Drake, Riley S.; Kolb, Kellie; Mead, Benjamin E.; Ahituv, Nadav; Martinez, Micaela E.; Shalek, Alex K.; Berger, Bonnie; Goods, Brittany A. 分享 收藏
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells Fardoos, Rabiah; Asowata, Osaretin E.; Herbert, Nicholas; Nyquist, Sarah K.; Zungu, Yenzekile; Singh, Alveera; Ngoepe, Abigail; Mbano, Ian M.; Mthabela, Ntombifuthi; Ramjit, Dirhona; Karim, Farina; Kuhn, Warren; Madela, Fusi G.; Manzini, Vukani T.; Anderson, Frank; Berger, Bonnie; Pers, Tune H.; Shalek, Alex K.; Leslie, Alasdair; Kloverpris, Henrik N. 分享 收藏
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics 跨组织和人口统计学的SARS-CoV-2进入基因的单细胞荟萃分析 Muus, Christoph; Luecken, Malte D.; Eraslan, Gokcen; Sikkema, Lisa; Waghray, Avinash; Heimberg, Graham; Kobayashi, Yoshihiko; Vaishnav, Eeshit Dhaval; Subramanian, Ayshwarya; Smillie, Christopher; Jagadeesh, Karthik A.; Duong, Elizabeth Thu; Fiskin, Evgenij; Triglia, Elena Torlai; Ansari, Meshal; Cai, Peiwen; Lin, Brian; Buchanan, Justin; Chen, Sijia; Shu, Jian; Haber, Adam L.; Chung, Hattie; Montoro, Daniel T.; Adams, Taylor; Aliee, Hananeh; Allon, Samuel J.; Andrusivova, Zaneta; Angelidis, Ilias; Ashenberg, Orr; Bassler, Kevin; Becavin, Christophe; Benhar, Inbal; Bergenstrahle, Joseph; Bergenstrahle, Ludvig; Bolt, Liam; Braun, Emelie; Bui, Linh T.; Callori, Steven; Chaffin, Mark; Chichelnitskiy, Evgeny; Chiou, Joshua; Conlon, Thomas M.; Cuoco, Michael S.; Cuomo, Anna S. E.; Deprez, Marie; Duclos, Grant; Fine, Denise; Fischer, David S.; Ghazanfar, Shila; Gillich, Astrid; Giotti, Bruno; Gould, Joshua; Guo, Minzhe; Gutierrez, Austin J.; Habermann, Arun C.; Harvey, Tyler; He, Peng; Hou, Xiaomeng; Hu, Lijuan; Hu, Yan; Jaiswal, Alok; Ji, Lu; Jiang, Peiyong; Kapellos, Theodoros S.; Kuo, Christin S.; Larsson, Ludvig; Leney-Greene, Michael A.; Lim, Kyungtae; Litvinukova, Monika; Ludwig, Leif S.; Lukassen, Soeren; Luo, Wendy; Maatz, Henrike; Madissoon, Elo; Mamanova, Lira; Manakongtreecheep, Kasidet; Leroy, Sylvie; Mayr, Christoph H.; Mbano, Ian M.; McAdams, Alexi M.; Nabhan, Ahmad N.; Nyquist, Sarah K.; Penland, Lolita; Poirion, Olivier B.; Poli, Sergio; Qi, CanCan; Queen, Rachel; Reichart, Daniel; Rosas, Ivan; Schupp, Jonas C.; Shea, Conor, V; Shi, Xingyi; Sinha, Rahul; Sit, Rene, V; Slowikowski, Kamil; Slyper, Michal; Smith, Neal P.; Sountoulidis, Alex; Strunz, Maximilian; Sullivan, Travis B.; Sun, Dawei; Talavera-Lopez, Carlos; Tan, Peng; Tantivit, Jessica; Travaglini, Kyle J.; Tucker, Nathan R.; Vernon, Katherine A.; Wadsworth, Marc H.; Waldman, Julia; Wang, Xiuting; Xu, Ke; Yan, Wenjun; Zhao, William; Ziegler, Carly G. K. 分享 收藏
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation 在2型炎症期间，人气道肥大细胞增殖并获得不同的炎症驱动表型 Dwyer, Daniel F.; Ordovas-Montanes, Jose; Allon, Samuel J.; Buchheit, Kathleen M.; Vukovic, Marko; Derakhshan, Tahereh; Feng, Chunli; Lai, Juying; Hughes, Travis K.; Nyquist, Sarah K.; Giannetti, Matthew P.; Berger, Bonnie; Bhattacharyya, Neil; Roditi, Rachel E.; Katz, Howard R.; Nawijn, Martijn C.; Berg, Marijn; van den Berge, Maarten; Laidlaw, Tanya M.; Shalek, Alex K.; Barrett, Nora A.; Boyce, Joshua A. 分享 收藏
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