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MESENCHYMAL STEM CELLS AND PERIVASCULAR STROMA ARE ASSOCIATED WITH MICROVASCULAR PROLIFERATION, IMMUNOSUPPRESSION, AND POOR OUTCOME IN GLIOMA 间充质干细胞和血管周基质与胶质瘤中的微血管增生、免疫抑制和不良预后相关 Poon, Candice; Herbrich, Shelley; Chen, Yulong; Hossain, Anwar; Fuller, Gregory; Jindal, Sonali; Basu, Sreyashi; Ledbetter, Daniel; Macaluso, Marc; Phillips, Lynnette; Gumin, Joy; He, Zhong; Parker-Kerrigan, Brittany; Singh, Sanjay; Singh, Pratishtha; Zamen, Mohammed Fayyad; Tang, Derek Ng; Goswami, Sangeeta; Lang, Frederick F.; Sharma, Padmanee 分享 收藏
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TSG-6+cancer-associated fibroblasts modulate myeloid cell responses and impair anti-tumor response to immune checkpoint therapy in pancreatic cancer Anandhan, Swetha; Herbrich, Shelley; Goswami, Sangeeta; Guan, Baoxiang; Chen, Yulong; Macaluso, Marc Daniel; Jindal, Sonali; Natarajan, Seanu Meena; Andrewes, Samuel W.; Xiong, Liangwen; Nagarajan, Ashwat; Basu, Sreyashi; Tang, Derek Ng; Liu, Jielin; Min, Jimin; Maitra, Anirban; Sharma, Padmanee 分享 收藏
In vivo CRISPR screening identifies PTDSS1 as a potential combinatorial target to improve immune checkpoint therapy response Liu, Jielin; Anandhan, Swetha; Basu, Sreyashi; Chen, Yulong; Goswami, Sangeeta; Nagarajan, Ashwat; Herbrich, Shelley; Xiong, Liangwen; Guan, Baoxiang; Sharma, Padmanee 分享 收藏
Heterogeneous nuclear ribonucleoprotein K is overexpressed in acute myeloid leukemia and causes myeloproliferation in mice via altered Runx1 splicing Aitken, Marisa J. L.; Malaney, Prerna; Zhang, Xiaorui; Herbrich, Shelley M.; Chan, Lauren; Benitez, Oscar; Rodriguez, Ashley G.; Ma, Huaxian; Jacamo, Rodrigo; Duan, Ruizhi; Link, Todd M.; Kornblau, Steven M.; Kanagal-Shamanna, Rashmi; Bueso-Ramos, Carlos E.; Post, Sean M. 分享 收藏
Triple combination targeting methyltransferase, BCL-2, and PD-1 facilitates antileukemia responses in acute myeloid leukemia Zeng, Zhihong; Maiti, Abhishek; Herbrich, Shelley; Cai, Tianyu; Cavazos, Antonio; Manzella, Taylor; Ma, Helen; Hayes, Kala; Matthews, Jairo; DiNardo, Courtney D. D.; Daver, Naval G. G.; Konopleva, Marina Y. Y. 分享 收藏
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia Baran, Natalia; Lodi, Alessia; Dhungana, Yogesh; Herbrich, Shelley; Collins, Meghan; Sweeney, Shannon; Pandey, Renu; Skwarska, Anna; Patel, Shraddha; Tremblay, Mathieu; Kuruvilla, Vinitha Mary; Cavazos, Antonio; Kaplan, Mecit; Warmoes, Marc O.; Veiga, Diogo Troggian; Furudate, Ken; Rojas-Sutterin, Shanti; Haman, Andre; Gareau, Yves; Marinier, Anne; Ma, Helen; Harutyunyan, Karine; Daher, May; Garcia, Luciana Melo; Al-Atrash, Gheath; Piya, Sujan; Ruvolo, Vivian; Yang, Wentao; Shanmugavelandy, Sriram Saravanan; Feng, Ningping; Gay, Jason; Du, Di; Yang, Jun J.; Hoff, Fieke W.; Kaminski, Marcin; Tomczak, Katarzyna; Eric Davis, R.; Herranz, Daniel; Ferrando, Adolfo; Jabbour, Elias J.; Emilia Di Francesco, M.; Teachey, David T.; Horton, Terzah M.; Kornblau, Steven; Rezvani, Katayoun; Sauvageau, Guy; Gagea, Mihai; Andreeff, Michael; Takahashi, Koichi; Marszalek, Joseph R.; Lorenzi, Philip L.; Yu, Jiyang; Tiziani, Stefano; Hoang, Trang; Konopleva, Marina 分享 收藏
Targeting the NRF2/HO-1 Antioxidant Pathway in FLT3-ITD-Positive AML Enhances Therapy Efficacy Kannan, Sankaranarayan; Irwin, Mary E.; Herbrich, Shelley M.; Cheng, Tiewei; Patterson, LaNisha L.; Aitken, Marisa J. L.; Bhalla, Kapil; You, M. James; Konopleva, Marina; Zweidler-McKay, Patrick A.; Chandra, Joya 分享 收藏
Overexpression of CD200 is a Stem Cell-Specific Mechanism of Immune Evasion in AML Herbrich, Shelley; Baran, Natalia; Cai, Tianyu; Weng, Connie; Aitken, Marisa J. L.; Post, Sean M.; Henderson, Jared; Shi, Chunhua; Havranek, Ondrej; Richard-Carpentier, Guillame; Sauvageau, Guy; Baggerly, Keith; Al-Atrash, Gheath; Davis, R. Eric; Daver, Naval; Zha, Dongxing; Konopleva, Marina 分享 收藏
A phase 1b/2 study of azacitidine with PD-L1 antibody avelumab in relapsed/refractory acute myeloid leukemia Saxena, Kapil; Herbrich, Shelley M.; Pemmaraju, Naveen; Kadia, Tapan M.; DiNardo, Courtney D.; Borthakur, Gautam; Pierce, Sherry A.; Jabbour, Elias; Wang, Sa A.; Bueso-Ramos, Carlos; Loghavi, Sanam; Tang, Guillin; Cheung, Cora M.; Alexander, Lynette; Kornblau, Steven; Andreeff, Michael; Garcia-Manero, Guillermo; Ravandi, Farhad; Konopleva, Marina Y.; Daver, Naval 分享 收藏
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Antileukemia Effects of Notch-Mediated Inhibition of Oncogenic PLK1 in B-Cell Acute Lymphoblastic Leukemia Kannan, Sankaranarayanan; Aitken, Marisa J. L.; Herbrich, Shelley M.; Golfman, Leonard S.; Hall, Mandy G.; Mak, Duncan H.; Burks, Jared K.; Song, Guangchun; Konopleva, Marina; Mullighan, Charles G.; Chandra, Joya; Zweidler-McKay, Patrick A. 分享 收藏
S63845, a novel BH3 mimetic Mcl-1 inhibitor synergizes with midostaurin to induce potent apoptosis in acute myeloid leukemia cells carrying FLT3-ITD mutations Skwarska, Anna; Zhang, Qi; Herbrich, Shelley M.; Baran, Natalia; Halilovic, Ensar; Ruvolo, Peter; Ruvolo, Vivian; Morris, Erick; Wei, Andrew; Moujalled, Donia; Andreff, Michael; Konopleva, Marina 分享 收藏
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Intragenic DNA methylation and increased gene expression: New directions from pan-cancer analysis McGuire, Michael H.; Herbrich, Shelley; Wu, Sherry; Wang, Ying; Rupaimoole, Rajesha; Yao, Hui; Gharpure, Kshipra; Lopez-Berestein, Gabriel; Baggerly, Keith; Sood, Anil 分享 收藏
Targeting the PI3K/AKT/mTOR pathway for the treatment of metaplastic breast cancer: Does location of PIK3CA mutation or histology affect response Basho, Reva K.; Gilcrease, Michael; Murthy, Rashmi K.; Helgason, Thorunn; Booser, Daniel J.; Karp, Daniel D.; Meric-Bernstam, Funda; Hess, Kenneth R.; Herbrich, Shelley M.; Valero, Vicente; Albarracin, Constance; Litton, Jennifer; -MacGregor, Mariana Chavez; Ibrahim, Nuhad K.; Murray, James L.; Koenig, Kimberly B.; Hong, David; Subbiah, Vivek; Kurzrock, Razelle; Janku, Filip; Moulder, Stacy 分享 收藏
A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer Wu, Sherry Y.; Rupaimoole, Rajesha; Shen, Fangrong; Pradeep, Sunila; Pecot, Chad V.; Ivan, Cristina; Nagaraja, Archana S.; Gharpure, Kshipra M.; Pham, Elizabeth; Hatakeyama, Hiroto; McGuire, Michael H.; Haemmerle, Monika; Vidal-Anaya, Viviana; Olsen, Courtney; Rodriguez-Aguayo, Cristian; Filant, Justyna; Ehsanipour, Ehsan A.; Herbrich, Shelley M.; Maiti, Sourindra N.; Huang, Li; Kim, Ji Hoon; Zhang, Xinna; Han, Hee-Dong; Armaiz-Pena, Guillermo N.; Seviour, Elena G.; Tucker, Sue; Zhang, Min; Yang, Da; Cooper, Laurence J. N.; Ali-Fehmi, Rouba; Bar-Eli, Menashe; Lee, Ju-Seog; Ram, Prahlad T.; Baggerly, Keith A.; Lopez-Berestein, Gabriel; Hung, Mien-Chie; Sood, Anil K. 分享 收藏
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