Po‐Huang Liang - Publications, H-index & Citations

Po‐Huang Liang

national taiwan university

52H指数

185论文数

8.6K被引数

收录论文 70

发表时间

Identification of a structural mechanism for prediction and discrimination of substrates for multifunctional GH5 cellulases/hemicellulases 鉴定一种用于预测和区分多功能GH5纤维素酶/半纤维素酶底物的结构机制

the febs journal

IF0

2026-06-05

PREAI

Jia-Jin Liu; I-Chen Liu; Yung-Yeh Chen; Tsung-Yi Lin; Po-Huang Liang

Targeting SARS-CoV-2 RNA-dependent RNA polymerase with the coumarin derivative BPR2-D2: Evidence from cell-based and enzymatic studies 靶向SARS-CoV-2 RNA依赖性RNA聚合酶的香豆素衍生物BPR2-D2：细胞实验和酶学研究证据

Biomedicine & Pharmacotherapy

IF7.5

2025-06-20

PREAI

Wen-Fang Tang; Hui-Ping Tsai; Yuan-Fan Chin; Shan-Ko Tsai; Cheng-Chin Lin; Son Tung Ngo; Po-Huang Liang; Jia-Rong Jheng; Chung-Fan Hsieh; Jin-Ching Lee; Yu-Hsiu Chang; Tein-Yao Chang; Chia-Yi Lin; Guan-Hua Lin; Jie-Yun Cai; Yu-Li Chen; Yuan-Siao Chen; Ping-Cheng Liu; Chuen-Mi Yang; Tolou Shadbahr; Jim-Tong Horng

Green Synthesis of Tetrahydropyrazino[2,1-a:5,4-a′]diisoquinolines as SARS-CoV-2 Entry Inhibitors

ACS OMEGA

IF4.3

2024-12-20

OAAI

Palla, Sowndarya; Palla, Srinivasa Rao; Liu, Jia-Jin; Chao, Tai-Ling; Lee, Ting-Hui; Kavala, Veerababurao; Liu, I-Chen; Wang, Lily Hui-Ching; Chang, Sui-Yuan; Yao, Ching-Fa; Liang, Po-Huang

Systematic Studies on the Anti-SARS-CoV-2 Mechanisms of Tea Polyphenol-Related Natural Products

ACS OMEGA

IF4.3

2024-05-17

OAAI

Li, Chen-Wei; Chao, Tai-Ling; Lai, Chin-Lan; Lin, Cheng-Chin; Pan, Max Yu-Chen; Cheng, Chieh-Ling; Kuo, Chih-Jung; Wang, Lily Hui-Ching; Chang, Sui-Yuan; Liang, Po-Huang

Non-Heme Iron Enzymes Catalyze Heterobicyclic and Spirocyclic Isoquinolone Core Formation in Piperazine Alkaloid Biosynthesis 非血红素铁酶催化哌嗪生物碱生物合成中的杂双环和螺环异喹诺酮核心形成

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-04-09

OAAI

Pham, Mai-Truc; Yang, Feng-Ling; Liu, I-Chen; Liang, Po-Huang; Lin, Hsiao-Ching

BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2024-04-03

PREAI

Tang, Wen-Fang; Chang, Yu-Hsiu; Lin, Cheng-Chin; Jheng, Jia-Rong; Hsieh, Chung-Fan; Chin, Yuan-Fan; Chang, Tein-Yao; Lee, Jin-Ching; Liang, Po-Huang; Lin, Chia-Yi; Lin, Guan-Hua; Cai, Jie-Yun; Chen, Yu-Li; Chen, Yuan-Siao; Tsai, Shan-Ko; Liu, Ping-Cheng; Yang, Chuen-Mi; Shadbahr, Tolou; Tang, Jing; Hsu, Yu-Lin; Huang, Chih-Heng; Wang, Ling-Yu; Chen, Cheng Cheung; Kau, Jyh-Hwa; Hung, Yi-Jen; Lee, Hsin-Yi; Wang, Wen-Chieh; Tsai, Hui-Ping; Horng, Jim-Tong

SARS-CoV-2 3CLpro displays faster self-maturation in vitro than SARS-CoV 3CLpro due to faster C-terminal cleavage

FEBS LETTERS

IF3

2022-03-28

PREAI

Kuo, Chih-Jung; Liang, Po-Huang

Drug Repurposing for the Identification of Compounds with Anti-SARS-CoV-2 Capability via Multiple Targets

PHARMACEUTICS

IF5.5

2022-01-12

OAAI

Yu, Pei-Chen; Huang, Chen-Hao; Kuo, Chih-Jung; Liang, Po-Huang; Wang, Lily Hui-Ching; Pan, Max Yu-Chen; Chang, Sui-Yuan; Chao, Tai-Ling; Ieong, Si-Man; Fang, Jun-Tung; Huang, Hsuan-Cheng; Juan, Hsueh-Fen

Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir

ACS CENTRAL SCIENCE

IF10.4

2021-04-15

OAAI

Lo, Ho Sing; Hui, Kenrie Pui Yan; Lai, Hei-Ming; He, Xu; Khan, Khadija Shahed; Kaur, Simranjeet; Huang, Junzhe; Li, Zhongqi; Chan, Anthony K. N.; Cheung, Hayley Hei-Yin; Ng, Ka-Chun; Ho, John Chi Wang; Chen, Yu Wai; Ma, Bowen; Cheung, Peter Man-Hin; Shin, Donghyuk; Wang, Kaidao; Lee, Meng-Hsuan; Selisko, Barbara; Eydoux, Cecilia; Guillemot, Jean-Claude; Canard, Bruno; Wu, Kuen-Phon; Liang, Po-Huang; Dikic, Ivan; Zuo, Zhong; Chan, Francis K. L.; Hui, David S. C.; Mok, Vincent C. T.; Wong, Kam-Bo; Mok, Chris Ka Pun; Ko, Ho; Aik, Wei Shen; Chan, Michael Chi Wai; Ng, Wai-Lung

Kinetic Characterization and Inhibitor Screening for the Proteases Leading to Identification of Drugs against SARS-CoV-2 蛋白酶的动力学特性和抑制剂筛选，从而鉴定抗SARS-CoV-2的药物

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2021-03-18

OAAI

Kuo, Chih-Jung; Chao, Tai-Ling; Kao, Han-Chieh; Tsai, Ya-Min; Liu, Yi-Kai; Wang, Lily Hui-Ching; Hsieh, Ming-Chang; Chang, Sui-Yuan; Liang, Po-Huang

Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing

ACS NANO

IF16

2020-12-29

OAAI

Pathak, Nikhil; Chen, Yun-Ti; Hsu, Yen-Chao; Hsu, Nung-Yu; Kuo, Chih-Jung; Tsai, Hui Ping; Kang, Jaw-Jou; Huang, Chih-Heng; Chang, Sui-Yuan; Chang, Yu-Hsiu; Liang, Po-Huang; Yang, Jinn-Moon

Targeting β-tubulin/CCT-β complex induces apoptosis and suppresses migration and invasion of highly metastatic lung adenocarcinoma

CARCINOGENESIS

IF2.9

2019-08-11

PREAI

Liu, Yan-Jin; Chang, Yu-Ju; Kuo, Yu-Ting; Liang, Po-Huang

Characterization of a Cis-Prenyltransferase from Lilium longiflorum Anther

MOLECULES

IF4.6

2019-07-26

OAAI

Yao, Jyun-Yu; Teng, Kuo-Hsun; Liu, Ming-Che; Wang, Co-Shine; Liang, Po-Huang

The Penetration Depth for Hanatoxin Partitioning into the Membrane Hydrocarbon Core Measured with Neutron Reflectivity

LANGMUIR

IF3.9

2018-07-09

PREAI

Hsieh, Meng-Hsuan; Huang, Po-Tsang; Liou, Horng-Huei; Liang, Po-Huang; Chen, Pei-Ming; Holt, Stephen A.; Yu, Isaac Furay; James, Michael; Shiau, Yu-Shuan; Lee, Ming-Tao; Lin, Tsang-Lang; Lou, Kuo-Long

Highly sensitive fluorogenic sensing of L-Cysteine in live cells using gelatin-stabilized gold nanoparticles decorated graphene nanosheets

SENSORS AND ACTUATORS B-CHEMICAL

IF7.7

2018-04-01

OAAI

Thirumalraj, Balamurugan; Dhenadhayalan, Namasivayam; Chen, Shen-Ming; Liu, Yan-Jin; Chen, Tse-Wei; Liang, Po-Huang; Lin, King-Chuen

Caspase-3, a key apoptotic protein, as a prognostic marker in gastric cancer after curative surgery

INTERNATIONAL JOURNAL OF SURGERY

IF10.1

2018-04-01

PREAI

Huang, Kuo-Hung; Fang, Wen-Liang; Li, Anna Fen-Yau; Liang, Po-Huang; Wu, Chew-Wun; Shy, Yi-Ming; Yang, Muh-Hwa

Disrupting CCT-β: β-tubulin selectively kills CCT-β overexpressed cancer cells through MAPKs activation

CELL DEATH & DISEASE

IF9.6

2017-09-14

OAAI

Liu, Yan-Jin; Kumar, Vathan; Lin, Yuan-Feng; Liang, Po-Huang

Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-07-01

OAAI

Kumar, Vathan; Tan, Kian-Pin; Wang, Ying-Ming; Lin, Sheng-Wei; Liang, Po-Huang

Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-02-01

OAAI

Yuan, Shuo-Fu; Wu, Tzu-Hui; Lee, Hsiao-Lin; Hsieh, Han-Yu; Lin, Wen-Ling; Yang, Barbara; Chang, Chih-Kang; Li, Qian; Gao, Jian; Huang, Chun-Hsiang; Ho, Meng-Chiao; Guo, Rey-Ting; Liang, Po-Huang

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2014-11-18

OAAI

Han, Xu; Chen, Chun-Chi; Kuo, Chih-Jung; Huang, Chun-Hsiang; Zheng, Yingying; Ko, Tzu-Ping; Zhu, Zhen; Feng, Xinxin; Wang, Ke; Oldfield, Eric; Wang, Andrew H. -J.; Liang, Po-Huang; Guo, Rey-Ting; Ma, Yanhe

研究方向