Wen-Biao Wu

Hunan University

H指数:15

被引数:972

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Modular Access to Bridgehead Heterocycle-Substituted Bicyclo[1.1.0]butanes via Late-Stage Functionalization of Alkynylbicyclo[1.1.0]butanes

通过炔基双环[1.1.0]丁烷的晚期官能团化实现桥头杂环取代的双环[1.1.0]丁烷的模块化合成

Chemistry–Methods

IF0

2026-04-030

OAAI

GLS1-RNA Polymerase II Axis Mediates Glutamine-Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High-Protein Diets

GLS1-RNA聚合酶II轴介导高蛋白饮食下谷氨酰胺依赖的酒精性肝病的肝保护作用

ADVANCED SCIENCE

IF14.1

2025-09-010

OAAI

Zinc-Catalyzed Enantioselective Formal (3+2) Cycloadditions of Bicyclobutanes with Imines: Catalytic Asymmetric Synthesis of Azabicyclo[2.1.1]hexanes

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-10-252

Enantioselective formal (3+3) cycloaddition of bicyclobutanes with nitrones enabled by asymmetric Lewis acid catalysis

NATURE COMMUNICATIONS

IF15.7

2024-09-136

OAAI

Switching between the [2π+2σ] and Hetero-[4π+2σ] Cycloaddition Reactivity of Bicyclobutanes with Lewis Acid Catalysts Enables the Synthesis of Spirocycles and Bridged Heterocycles

双环丁烷与路易斯酸催化剂的 [2 π 2 σ] 和杂 [4 π 2 σ] 环加成反应性之间的切换可以合成螺环和桥接杂环

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-06-178

PRE

Palladium-Catalyzed Ligand-Controlled Switchable Hetero-(5+3)/Enantioselective [2σ+2σ] Cycloadditions of Bicyclobutanes with Vinyl Oxiranes

钯催化的配体控制的可切换杂-(5 3)/对映选择性 [2 σ2 σ] 双环丁烷与乙烯基环氧乙烷的环加成

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-05-1322

PRE

Enantioselective dearomative formal (3+3) cycloadditions of bicyclobutanes with aromatic azomethine imines: access to fused 2,3-diazabicyclo[3.1.1]heptanes

CHEMICAL SCIENCE

IF7.4

2024-01-012

OAAI

Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway

ACTA PHARMACOLOGICA SINICA

IF8.4

2023-06-147

Photochemical α-selective radical ring-opening reactions of 1,3-disubstituted acyl bicyclobutanes with alkyl halides: modular access to functionalized cyclobutenes

CHEMICAL SCIENCE

IF7.4

2023-01-0117

OAAI

C(sp²)–H cyclobutylation of hydroxyarenes enabled by silver-π-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes

Chemical Science

IF7.4

2023-01-0123

OAAI

The Bifunctional Silyl Reagent Me2(CH2Cl)SiCF3 Enables Highly Enantioselective Ketone Trifluoromethylation and Related Tandem Processes

双功能甲硅烷基试剂Me2(CH2Cl)SiCF3可实现高度对映选择性的酮三氟甲基化和相关的串联过程

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2022-08-1012

PRE

Constructing Tertiary Alcohols with Vicinal Stereocenters: Highly Diastereo- and Enantioselective Cyanosilylation of α-Branched Acyclic Ketones and Their Kinetic Resolution

构建具有邻位立体中心的叔醇: α-支链无环酮的高度非对映和对映选择性氰基甲硅烷基化及其动力学拆分

CCS CHEMISTRY

IF9.2

2022-06-0623

Targeting Glutamine Metabolism Ameliorates Autoimmune Hepatitis via Inhibiting T Cell Activation and Differentiation

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-1919

OAAI

Me2(CH2 = CH)SiCN: a bifunctional ethylene equivalent for Diels-Alder reaction based controllable tandem synthesis

CHEMICAL SCIENCE

IF7.4

2022-01-015

OAAI

Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies

ACTA PHARMACOLOGICA SINICA

IF8.4

2021-03-297

OAAI

Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia

口服可生物利用的抗急性髓系白血病CHK1抑制剂的设计，合成和生物学评价

CHEMMEDCHEM

IF3.4

2021-02-164

PREAI

Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma

ACTA PHARMACOLOGICA SINICA

IF8.4

2020-08-276

OAAI

Catalytic Enantioselective Cyanation: Recent Advances and Perspectives

ACS CATALYSIS

IF13.1

2020-06-1289

PREAI

Carbonyl-Stabilized Phosphorus Ylide as an Organocatalyst for Cyanosilylation Reactions Using TMSCN

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2020-02-2819

PREAI

Activation of Chiral (Salen)TiCl2 Complex by Phosphorane for the Highly Enantioselective Cyanation of Nitroolefins

ORGANIC LETTERS

IF5

2020-02-2731

PREAI

Wen-Biao Wu

个人简介

教育背景

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