Rui Huang

University of Guelph

H指数:21

被引数:1,783

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Extending Small-Molecule Aptamer Discovery Principles to Protein Targets: Selection and Characterization of Green Fluorescent Protein Aptamers

将小分子适配体发现原理扩展至蛋白质靶标：绿色荧光蛋白适配体的筛选与表征

Angewandte Chemie-International Edition

IF16.9

2026-09-300

OAAI

Characterization of Conformational Dynamics and Structural Plasticity of the Catalytic Domain of Human Mitochondrial YME1L Protease

人源线粒体YME1L蛋白酶催化结构域的构象动力学及结构可塑性的表征

Biochemistry

IF3

2026-02-260

PRE

NMR Insights into the Structural Dynamics of p47, a key Adaptor Protein of p97 in Golgi Reassembly

NMR对p97在Golgi重组中的关键适配器蛋白p47结构动力学的研究

Journal of Molecular Biology

IF4.5

2025-07-260

OAAI

A multidimensional strategy for uncovering comprehensive quality markers of Scutellariae Radix based on UPLC-Q-TOF-MS analysis, artificial neural network, network pharmacology analysis, and molecular simulation

FRONTIERS IN PLANT SCIENCE

IF4.8

2024-07-030

OAAI

S1PR2 Regulates Autophagy Through the AKT/mTOR Pathway to Promote Pathological Damage in Alzheimer's Disease

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2023-12-062

PRE

Sennoside A restrains TRAF6 level to modulate ferroptosis, inflammation and cognitive impairment in aging mice with Alzheimer's Disease

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2023-07-0112

PRE

An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase

内在无序的基序调节p47衔接子和p97 AAA ATPase之间的相互作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-10-0724

OAAI

Probing Cooperativity of N-Terminal Domain Orientations in the p97 Molecular Machine: Synergy Between NMR Spectroscopy and Cryo-EM

探测p97分子机器中N端结构域取向的协同性: NMR光谱与cryo-em之间的协同作用

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2020-10-066

PREAI

Exploring long-range cooperativity in the 20S proteasome core particle from Thermoplasma acidophilum using methyl-TROSY-based NMR

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-02-2414

OAAI

A Methyl-TROSY-Based 1H Relaxation Dispersion Experiment for Studies of Conformational Exchange in High Molecular Weight Proteins

基于甲基-TROSY的1h弛豫分散实验，用于研究高分子量蛋白质的构象交换

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2019-04-0432

PREAI

Cooperative subunit dynamics modulate p97 function

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-2429

OAAI

Unusual multiscale mechanics of biomimetic nanoparticle hydrogels

NATURE COMMUNICATIONS

IF15.7

2018-01-1231

OAAI

Probing the cooperativity of Thermoplasma acidophilum proteasome core particle gating by NMR spectroscopy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-10-3019

OAAI

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-09-11356

OAAI

Structure of a AAA plus unfoldase in the process of unfolding substrate

底物展开过程中AAA加unfolase的结构

ELIFE

IF0

2017-04-08120

Unfolding the mechanism of the AAA plus unfoldase VAT by a combined cryo-EM, solution NMR study

通过组合的cryo-em，溶液NMR研究来展开AAA加unfolase VAT的机理

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-07-1152

OAAI

Reconstitution of the Cytb5-CytP450 Complex in Nanodiscs for Structural Studies using NMR Spectroscopy

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2016-02-2978

PREAI

Effects of Membrane Mimetics on Cytochrome P450-Cytochrome b5 Interactions Characterized by NMR Spectroscopy

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-05-0132

OAAI

Insights into the Role of Substrates on the Interaction between Cytochrome b5 and Cytochrome P450 2B4 by NMR

SCIENTIFIC REPORTS

IF3.9

2015-02-1725

OAAI

Kinetic and Structural Characterization of the Interaction between the FMN Binding Domain of Cytochrome P450 Reductase and Cytochrome c

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-02-0126

OAAI

Rui Huang

个人简介

教育背景

工作经历

荣誉奖项

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