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Alterations along the neuroendocrine axis of leptin homeostasis: white adipose tissue and hypothalamus in a severe SMA mouse model 瘦素稳态的神经内分泌轴改变：严重SMA小鼠模型中的白色脂肪组织和下丘脑 Bunermann, Ines; Detering, Nora; Tapken, Ines; Kuhn, Daniela; Jahn, Kirsten; Burkert, Alexandra; Naczinsky, Sarah; Hensel, Niko; Schuning, Tobias; Dittrich-Breiholz, Oliver; Pich, Andreas; Claus, Peter 分享 收藏
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Aggregates associated with amyotrophic lateral sclerosis sequester the actin-binding protein profilin 2 与肌萎缩性侧索硬化症相关的聚集体隔离了肌动蛋白结合蛋白profilin 2 Kubinski, Sabrina; Claus, Luisa; Schuening, Tobias; Zeug, Andre; Kalmbach, Norman; Staege, Selma; Gschwendtberger, Thomas; Petri, Susanne; Wegner, Florian; Claus, Peter; Hensel, Niko 分享 收藏
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An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells Kyriazi, Despoina; Voth, Lea; Bader, Almke; Ewert, Wiebke; Gerlach, Juliane; Elfrink, Kerstin; Franz, Peter; Tsap, Mariana I.; Schirmer, Bastian; Damiano-Guercio, Julia; Hartmann, Falk K.; Plenge, Masina; Salari, Azam; Schoettelndreier, Dennis; Strienke, Katharina; Bresch, Nadine; Salinas, Claudio; Gutzeit, Herwig O.; Schaumann, Nora; Hussein, Kais; Baehre, Heike; Bruesch, Inga; Claus, Peter; Neumann, Detlef; Taft, Manuel H.; Shcherbata, Halyna R.; Ngezahayo, Anaclet; Baehler, Martin; Amiri, Mahdi; Knoelker, Hans-Joachim; Preller, Matthias; Tsiavaliaris, Georgios 分享 收藏
Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies He, Hai; Gomez-Coronado, Paul A.; Zarzycki, Jan; Barthel, Sebastian; Kahnt, Joerg; Claus, Peter; Klein, Moritz; Klose, Melanie; de Crecy-Lagard, Valerie; Schindler, Daniel; Paczia, Nicole; Glatter, Timo; Erb, Tobias J. 分享 收藏
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The systemic complexity of a monogenic disease: the molecular network of spinal muscular atrophy Tapken, Ines; Schweitzer, Theresa; Paganin, Martina; Schuening, Tobias; Detering, Nora T.; Sharma, Gaurav; Niesert, Moritz; Saffari, Afshin; Kuhn, Daniela; Glynn, Amy; Cieri, Federica; Santonicola, Pamela; Cannet, Claire; Gerstner, Florian; Faller, Kiterie M. E.; Huang, Yu-Ting; Kothary, Rashmi; Gillingwater, Thomas H.; Di Schiavi, Elia; Simon, Christian M.; Hensel, Niko; Ziegler, Andreas; Viero, Gabriella; Pich, Andreas; Claus, Peter 分享 收藏
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From data to discovery: AI-guided analysis of disease-relevant molecules in spinal muscular atrophy (SMA) 从数据到发现: AI指导的脊髓性肌萎缩症 (SMA) 疾病相关分子分析 Tapken, Ines; Kuhn, Daniela; Hoffmann, Nico; Detering, Nora T.; Schuening, Tobias; Billaud, Jean-Noel; Tugendreich, Stuart; Schlueter, Nadine; Green, Jeff; Kraemer, Andreas; Claus, Peter 分享 收藏
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A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models Hoolachan, Joseph M.; Mccallion, Eve; Sutton, Emma R.; Cetin, Ozge; Pacheco-Torres, Paloma; Dimitriadi, Maria; Sari, Suat; Miller, Gavin J.; Okoh, Magnus; Walter, Lisa M.; Claus, Peter; Wood, Matthew J. A.; Tonge, Daniel P.; Bowerman, Melissa 分享 收藏
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The Proteome Signatures of Fibroblasts from Patients with Severe, Intermediate and Mild Spinal Muscular Atrophy Show Limited Overlap 来自严重，中度和轻度脊髓性肌萎缩症患者的成纤维细胞的蛋白质组特征显示出有限的重叠 Brown, Sharon J.; Kline, Rachel A.; Synowsky, Silvia A.; Shirran, Sally L.; Holt, Ian; Sillence, Kelly A.; Claus, Peter; Wirth, Brunhilde; Wishart, Thomas M.; Fuller, Heidi R. 分享 收藏
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