András Gruber - Publications, H-index & Citations

András Gruber

Aronora Inc.

54H指数

211论文数

8.0K被引数

收录论文 76

发表时间

The Factor XIa Antibody Osocimab Strongly Inhibits Clotting in Extracorporeal Circuits with human blood and in baboons 因子XIa抗体Osocimab在含人血的体外循环回路中以及在对狒狒中均强烈抑制凝血。

Research and Practice in Thrombosis and Haemostasis

IF3.4

2025-06-01

OAAI

Eslam Samaha; Michael Schwameis; Sabine Schranz; Katarina D. Kovacevic; Bruno Watschinger; Martin Stoiber; Christopher Wolf; Michael Wallisch; András Gruber; Erik I. Tucker; Anja Buchmüller; Bernd Jilma

Safety and tolerability of the protein C activator AB002 in end-stage renal disease patients on hemodialysis: a randomized phase 2 trial 蛋白C激活剂AB002在血液透析终末期肾病患者中的安全性和耐受性: 一项随机2期试验

COMMUNICATIONS MEDICINE

IF6.3

2024-07-26

OAAI

Verbout, Norah G.; Lorentz, Christina U.; Markway, Brandon D.; Wallisch, Michael; Marbury, Thomas C.; Di Cera, Enrico; Shatzel, Joseph J.; Gruber, Andras; Tucker, Erik I.

New Directions in Infection-Associated Ischemic Stroke

JOURNAL OF CLINICAL NEUROLOGY

IF3.1

2024-01-01

OAAI

Jung, Jin-Man; Gruber, Andras; Heseltine, Peter; Rajamani, Kumar; Ameriso, Sebastian F.; Fisher, Mark J.

A novel mouse whole blood thrombin generation assay sensitive to FXI- and FIX-mediated amplification of coagulation

BLOOD ADVANCES

IF7.1

2023-05-09

OAAI

Wan, Jun; Tanratana, Pansakorn; Roest, Mark; Gruber, Andras; Pawlinski, Rafal; Wolberg, Alisa S.; Mackman, Nigel; Grover, Steven P.

Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-02-01

OAAI

Morla, Shravan; Deguchi, Hiroshi; Zilberman-Rudenko, Jevgenia; Gruber, Andras; McCarty, Owen J. T.; Srivastava, Priyanka; Gailani, David; Griffin, John H.

Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H

JOURNAL OF IMMUNOLOGY

IF3.4

2021-04-15

OAAI

Puy, Cristina; Pang, Jiaqing; Reitsma, Stephanie E.; Lorentz, Christina U.; Tucker, Erik, I; Gailani, David; Gruber, Andras; Lupu, Florea; McCarty, Owen J. T.

Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2021-04-01

OAAI

Ngo, Anh T. P.; Jordan, Kelley R.; Mueller, Paul A.; Hagen, Matthew W.; Reitsma, Stephanie E.; Puy, Cristina; Revenko, Alexey S.; Lorentz, Christina U.; Tucker, Erik I.; Cheng, Quifang; Hinds, Monica T.; Fazio, Sergio; Monia, Brett P.; Gailani, David; Gruber, Andras; Tavori, Hagai; McCarty, Owen J. T.

Role of platelets in regulating activated coagulation factor XI activity

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2021-03-01

OAAI

Reitsma, Stephanie E.; Pang, Jiaqing; Raghunathan, Vikram; Shatzel, Joseph J.; Lorentz, Christina U.; Tucker, Erik, I; Gruber, Andras; Gailani, David; McCarty, Owen J. T.; Puy, Cristina

Thrombin generation and activity in multiple sclerosis

METABOLIC BRAIN DISEASE

IF3.5

2021-01-07

OAAI

Jordan, Kelley R.; Parra-Izquierdo, Ivan; Gruber, Andras; Shatzel, Joseph J.; Pham, Peter; Sherman, Larry S.; McCarty, Owen J. T.; Verbout, Norah G.

The evolution of factor XI and the kallikrein-kinin system

BLOOD ADVANCES

IF7.1

2020-12-11

OAAI

Ponczek, Michal B.; Shamanaev, Aleksandr; LaPlace, Alec; Dickeson, S. Kent; Srivastava, Priyanka; Sun, Mao-fu; Gruber, Andras; Kastrup, Christian; Emsley, Jonas; Gailani, David

The contact activation system as a potential therapeutic target in patients with COVID-19

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2020-05-01

OAAI

Shatzel, Joseph J.; DeLoughery, Emma P.; Lorentz, Christina U.; Tucker, Erik I.; Aslan, Joseph E.; Hinds, Monica T.; Gailani, David; Weitz, Jeffrey I.; McCarty, Owen J. T.; Gruber, Andras

Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS

IF3.4

2020-02-01

OAAI

Wallisch, Michael; Lorentz, Christina U.; Lakshmanan, Hari H. S.; Johnson, Jennifer; Carris, Marschelle R.; Puy, Cristina; Gailani, David; Hinds, Monica T.; McCarty, Owen J. T.; Gruber, Andras; Tucker, Erik, I

Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice

BLOOD ADVANCES

IF7.1

2019-10-22

OAAI

Shirai, Toshiaki; Revenko, Alexey S.; Tibbitts, Justin; Ngo, Anh T. P.; Mitrugno, Annachiara; Healy, Laura D.; Johnson, Jennifer; Tucker, Erik I.; Hinds, Monica T.; Coussens, Lisa M.; McCarty, Owen J. T.; Monia, Brett P.; Gruber, Andras

A non-circulating pool of factor XI associated with glycosaminoglycans in mice

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2019-09-01

OAAI

Mohammed, Bassem M.; Cheng, Qiufang; Matafonov, Anton; Verhamme, Ingrid M.; Emsley, Jonas; McCrae, Keith R.; McCarty, Owen J. T.; Gruber, Andras; Gailani, David

Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI)

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2019-07-01

OAAI

Puy, Cristina; Ngo, Anh T. P.; Pang, Jiaqing; Keshari, Ravi S.; Hagen, Matthew W.; Hinds, Monica T.; Gailani, David; Gruber, Andras; Lupu, Florea; McCarty, Owen J. T.

Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2019-04-01

OAAI

Lorentz, Christina U.; Verbout, Norah G.; Wallisch, Michael; Hagen, Matthew W.; Shatzel, Joseph J.; Olson, Sven R.; Puy, Cristina; Hinds, Monica T.; McCarty, Owen J. T.; Gailani, David; Gruber, Andras; Tucker, Erik I.

Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death

BLOOD ADVANCES

IF7.1

2019-02-26

OAAI

Silasi, Robert; Keshari, Ravi Shankar; Lupu, Cristina; Van Rensburg, Walter Janse; Chaaban, Hala; Regmi, Girija; Shamanaev, Aleksandr; Shatzel, Joseph J.; Puy, Cristina; Lorentz, Christina U.; Tucker, Erik I.; Gailani, David; Gruber, Andras; McCarty, Owen J. T.; Lupu, Florea

The role of coagulation and platelets in colon cancer-associated thrombosis 凝血和血小板在结肠癌相关血栓形成中的作用

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2019-02-01

OAAI

Mitrugno, Annachiara; Yunga, Samuel Tassi; Sylman, Joanna L.; Zilberman-Rudenko, Jevgenia; Shirai, Toshiaki; Hebert, Jessica F.; Kayton, Robert; Zhang, Ying; Nan, Xiaolin; Shatzel, Joseph J.; Esener, Sadik; Duvernay, Matthew T.; Hamm, Heidi E.; Gruber, Andras; Williams, Craig D.; Takata, Yumie; Armstrong, Randall; Morgan, Terry K.; McCarty, Owen J. T.

Plasma contact factors as therapeutic targets

BLOOD REVIEWS

IF5.7

2018-11-01

OAAI

Tillman, Benjamin F.; Gruber, Andras; McCarty, Owen J. T.; Gailani, David

Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2018-08-01

OAAI

Zilberman-Rudenko, Jevgenia; Reitsma, Stephanie E.; Puy, Cristina; Rigg, Rachel A.; Smith, Stephanie A.; Tucker, Erik I.; Silasi, Robert; Merkulova, Alona; McCrae, Keith R.; Maas, Coen; Urbanus, Rolf T.; Gailani, David; Morrissey, James H.; Gruber, Andras; Lupu, Florea; Schmaier, Alvin H.; McCarty, Owen J. T.

研究方向