Roger N. Gunn - Publications, H-index & Citations

Roger N. Gunn

mitro

76H指数

455论文数

2.5W被引数

收录论文 170

发表时间

Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale

Annals of Neurology

IF7.7

2026-01-20

OAAI

Zhen Fan PhD; Graham Searle PhD; Gaia Rizzo PhD; Justin Albani BSc; Patrick Cella MSc; Robert Comley MSc; Gregory Klein PhD; Luca Passamonti MD, PhD; Cristian Salinas PhD; Adam J. Schwarz PhD; Leonardo Iaccarino PhD; Gilles Tamagnan PhD; Jamie Eberling PhD; Ken Marek MD; John Seibyl MD; Roger N. Gunn PhD; The Parkinson's Progression Markers Initiative

Interplay between astrocyte reactivity and APOE ε4 status is associated with accelerated pTau-related tau pathology in Alzheimer’s disease 星形胶质细胞反应性与APOE ε4状态之间的相互作用与阿尔茨海默病中加速的pTau相关tau病理有关

Molecular Neurodegeneration

IF17.5

2025-10-31

OAAI

Xiaoxie Mao; Yan Wang; Ying Luan; Ying Wang; Jie Wang; Wenlin Dai; Yihui Guan; Qi Huang; Roger N. Gunn; Rik Ossenkoppele; Binyin Li; Zijing Li; Qihao Guo; Fang Xie

An in vivo PET/CT investigation of mitochondrial complex 1, sigma 1, and synaptic vesicle 2 A in patients with amyotrophic lateral sclerosis 一项在体PET/CT研究，探讨肌萎缩侧索硬化症患者中的线粒体复合物1、σ1受体和突触囊泡2A的情况

Neurobiology of Disease

IF5.6

2025-10-09

OAAI

Edoardo R. de Natale; Joji P. Verghese; Alana Terry; Heather Wilson; Pegah Khosropanah; Holly Wright; Luca Passamonti; Karleyton C. Evans; Robert A. Comley; Hideo Tsukada; Jan Passchier; Graham Searle; Ekaterina Pererva; Alex Whittington; Roger Gunn; Eugenii A. Rabiner; Marios Politis

EC ₅₀ images reveal reproducible spatial variation in drug affinity across single- and repeat-dose occupancy studies EC₅₀图像揭示了在单次剂量和重复剂量占有率研究中药物亲和力的可重复空间变化。

Journal of Cerebral Blood Flow & Metabolism

IF4.5

2025-06-25

PREAI

Alaaddin Ibrahimy; Su Jin Kim; Mark E Schmidt; Mark Slifstein; Erik Mannaert; Randolph D Andrews; Dawn C Matthews; Cristian C Constantinescu; Graham E Searle; Roger N Gunn; Eugenii A Rabiner; Evan D Morris

The relationship between cortical synaptic terminal density marker SV2A and glutamate early in the course of schizophrenia: a multimodal PET and MRS imaging study

TRANSLATIONAL PSYCHIATRY

IF6.2

2025-03-01

OAAI

Onwordi, Ellis Chika; Whitehurst, Thomas; Shatalina, Ekaterina; Carr, Richard; Mansur, Ayla; Arumuham, Atheeshaan; Osugo, Martin; Marques, Tiago Reis; Jauhar, Sameer; Gupta, Susham; Pappa, Sofia; Mehrotra, Ravi; Ranger, Maja; Rahaman, Nikola; Rabiner, Eugenii A.; Gunn, Roger N.; Natesan, Sridhar; Howes, Oliver D.

Mitochondria and Cognition: An [18F]BCPP-EF Positron Emission Tomography Study of Mitochondrial Complex I Levels and Brain Activation During Task Switching 线粒体与认知：一项关于任务转换期间线粒体复合物I水平与脑激活的[18F]BCPP-EF正电子发射断层扫描研究

biological psychiatry cognitive neuroscience and neuroimaging

IF0

2025-02-24

OAAI

Ekaterina Shatalina; Thomas Whitehurst; Ellis Chika Onwordi; Alexander Whittington; Ayla Mansur; Atheeshaan Arumuham; Tiago Reis Marques; Roger N. Gunn; Sridhar Natesan; Matthew M. Nour; Eugenii A. Rabiner; Matthew B. Wall; Oliver D. Howes

Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study (05 Jan, 10.1038/s41386-024-02046-3, 2025)

NEUROPSYCHOPHARMACOLOGY

IF7.1

2025-01-22

OAAI

Terry-Lorenzo, Ryan; Albrecht, Daniel; Crouch, Sabrinia; Wong, Richard; Loewen, Gordon; Giri, Nagdeep; Skor, Heather; Lin, Kelly; Sandiego, Christine M.; Pajonas, Meghan; Rabiner, Eugenii A.; Gunn, Roger N.; Russell, David S.; Haubenberger, Dietrich

Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study

NEUROPSYCHOPHARMACOLOGY

IF7.1

2025-01-05

PREAI

Discovery and clinical translation of ceperognastat, an O-GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS

IF6.8

2024-12-26

OAAI

Kielbasa, William; Goldsmith, Paul; Donnelly, Kevin B.; Nuthall, Hugh N.; Shcherbinin, Sergey; Fleisher, Adam S.; Hendle, Jorg; Dubois, Susan L.; Lowe, Stephen L.; Zhang, Feiyu Fred; Woerly, Eric M.; Dreyfus, Nicolas J. -F.; Evans, David; Gilmore, Jeremy; Mancini, Michele; Constantinescu, Cristian C.; Gunn, Roger N.; Russell, David S.; Collins, Emily C.; Brys, Miroslaw; Hutton, Michael L.; Mergott, Dustin J.

Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model

ALZHEIMERS & DEMENTIA

IF11.1

2024-07-23

OAAI

Leuzy, Antoine; Raket, Lars Lau; Villemagne, Victor L.; Klein, Gregory; Tonietto, Matteo; Olafson, Emily; Baker, Suzanne; Saad, Ziad S.; Bullich, Santiago; Lopresti, Brian; Bohorquez, Sandra Sanabria; Boada, Merce; Betthauser, Tobey J.; Charil, Arnaud; Collins, Emily C.; Collins, Jessica A.; Cullen, Nicholas; Gunn, Roger N.; Higuchi, Makoto; Hostetler, Eric; Hutchison, R. Matthew; Iaccarino, Leonardo; Insel, Philip S.; Irizarry, Michael C.; Jack, Clifford R.; Jagust, William J.; Johnson, Keith A.; Johnson, Sterling C.; Karten, Yashmin; Marquie, Marta; Mathotaarachchi, Sulantha; Mintun, Mark A.; Ossenkoppele, Rik; Pappas, Ioannis; Petersen, Ronald C.; Rabinovici, Gil D.; Rosa-Neto, Pedro; Schwarz, Christopher G.; Smith, Ruben; Stephens, Andrew W.; Whittington, Alex; Carrillo, Maria C.; Pontecorvo, Michael J.; Haeberlein, Samantha Budd; Dunn, Billy; Kolb, Hartmuth C.; Sivakumaran, Sudhir; Rowe, Christopher C.; Hansson, Oskar; Dore, Vincent

Synaptic Terminal Density Early in the Course of Schizophrenia: An In Vivo UCB-J Positron Emission Tomographic Imaging Study of SV2A

BIOLOGICAL PSYCHIATRY

IF9

2024-04-01

OAAI

Onwordi, Ellis Chika; Whitehurst, Thomas; Shatalina, Ekaterina; Mansur, Ayla; Arumuham, Atheeshaan; Osugo, Martin; Marques, Tiago Reis; Jauhar, Sameer; Gupta, Susham; Mehrotra, Ravi; Rabiner, Eugenii A.; Gunn, Roger N.; Natesan, Sridhar; Howes, Oliver D.

Estimation of target occupancy in repeated dosing design studies using positron emission tomography: Biases due to target upregulation

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

IF4.5

2023-11-09

OAAI

Rabiner, Eugenii A.; Gunn, Roger N.

Validation of quantitative assessment of florbetaben PET scans as an adjunct to the visual assessment across 15 software methods

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2023-06-10

OAAI

Jovalekic, Aleksandar; Roe-Vellve, Nuria; Koglin, Norman; Quintana, Mariana Lagos; Nelson, Aaron; Diemling, Markus; Lilja, Johan; Gomez-Gonzalez, Juan Pablo; Dore, Vincent; Bourgeat, Pierrick; Whittington, Alex; Gunn, Roger; Stephens, Andrew W.; Bullich, Santiago

Brain Serotonin Release Is Reduced in Patients With Depression: A [11C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge

BIOLOGICAL PSYCHIATRY

IF9

2023-06-01

OAAI

Erritzoe, David; Godlewska, Beata R.; Rizzo, Gaia; Searle, Graham E.; Agnorelli, Claudio; Lewis, Yvonne; Ashok, Abhishekh H.; Colasanti, Alessandro; Boura, Iro; Farrell, Chloe; Parfitt, Hollie; Howes, Oliver; Passchier, Jan; Gunn, Roger N.; Politis, Marios; Nutt, David J.; Cowen, Philip J.; Knudsen, Gitte M.; Rabiner, Eugenii A.

Application of Aligned-UMAP to longitudinal biomedical studies

PATTERNS

IF7.4

2023-06-01

OAAI

Dadu, Anant; Satone, Vipul K.; Kaur, Rachneet; Koretsky, Mathew J.; Iwaki, Hirotaka; Qi, Yue A.; Ramos, Daniel M.; Avants, Brian; Hesterman, Jacob; Gunn, Roger; Cookson, Mark R.; Ward, Michael E.; Singleton, Andrew B.; Campbell, Roy H.; Nalls, Mike A.; Faghri, Faraz

A PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod 参加拉喹莫德随机试验的亨廷顿病患者神经炎症的pet-ct研究

BRAIN COMMUNICATIONS

IF4.5

2023-04-03

OAAI

Roussakis, Andreas-Antonios; Gennaro, Marta; Gordon, Mark Forrest; Reilmann, Ralf; Borowsky, Beth; Rynkowski, Gail; Lao-Kaim, Nicholas P.; Papoutsou, Zoe; Savola, Juha-Matti; Hayden, Michael R.; Owen, David R.; Kalk, Nicola; Lingford-Hughes, Anne; Gunn, Roger N.; Searle, Graham; Tabrizi, Sarah J.; Piccini, Paola

Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability

BRAIN COMMUNICATIONS

IF4.5

2022-10-21

OAAI

Ng, Bryan; Rowland, Helen A.; Wei, Tina; Arunasalam, Kanisa; Hayes, Emma Mee; Koychev, Ivan; Hedegaard, Anne; Ribe, Elena M.; Chan, Dennis; Chessell, Tharani; Ffytche, Dominic; Gunn, Roger N.; Kocagoncu, Ece; Lawson, Jennifer; Malhotra, Paresh A.; Ridha, Basil H.; Rowe, James B.; Thomas, Alan J.; Zamboni, Giovanna; Buckley, Noel J.; Cader, Zameel M.; Lovestone, Simon; Wade-Martins, Richard

A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET

JOURNAL OF NUCLEAR MEDICINE

IF9.1

2022-09-29

OAAI

Seibyl, John P.; DuBois, Jonathan M.; Racine, Annie; Collins, Jessica; Guo, Qi; Wooten, Dustin; Stage, Eddie; Cheng, David; Gunn, Roger N.; Porat, Lilly; Whittington, Alex; Kuo, Phillip H.; Ichise, Masanori; Comley, Robert; Martarello, Laurent; Salinas, Cristian

Astrogliosis in aging and Parkinson's disease dementia: a new clinical study with 11C-BU99008 PET

BRAIN COMMUNICATIONS

IF4.5

2022-08-18

OAAI

Mohamed, Mohamed A.; Zeng, Zhou; Gennaro, Marta; Lao-Kaim, Nicholas P.; Myers, Jim F. M.; Calsolaro, Valeria; Femminella, Grazia Daniela; Tyacke, Robin J.; Martin-Bastida, Antonio; Gunn, Roger N.; Nutt, David J.; Edison, Paul; Piccini, Paola; Roussakis, Andreas-Antonios

Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease 早期阿尔茨海默病患者发生广泛的细胞应激和线粒体功能障碍

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2022-08-17

OAAI

Venkataraman, Ashwin V.; Mansur, Ayla; Rizzo, Gaia; Bishop, Courtney; Lewis, Yvonne; Kocagoncu, Ece; Lingford-Hughes, Anne; Huiban, Mickael; Passchier, Jan; Rowe, James B.; Tsukada, Hideo; Brooks, David J.; Martarello, Laurent; Comley, Robert A.; Chen, Laigao; Schwarz, Adam J.; Hargreaves, Richard; Gunn, Roger N.; Rabiner, Eugenii A.; Matthews, Paul M.

研究方向