David J. A. Wyllie - Publications, H-index & Citations

Absence of GluN2A in hippocampal CA1 neurons leads to altered dendritic structure and reduced frequency of miniature excitatory synaptic events GluN2A在 hippocampal CA1 神经元中的缺失会导致树突结构改变和微小兴奋性突触事件的频率降低

IF5.5

2025-05-26

OAAI

Eleftheriou, Constantinos; Giachetti, Sarah; Hickson, Raven; Kamnioti-Dumont, Laura; Templaar, Robert; Aaltonen, Alina; Tsoukala, Eleni; Kim, Nawon; Fryer-Petridis, Lysandra; Henley, Chloe; Erdem, Ceren; Wilson, Emma; Maio, Beatriz; Ye, Jingjing; Pierce, Jessica C.; Mazur, Kath; Landa-Navarro, Lucia; Petrovic, Nina G.; Bendova, Sarah; Woods, Hanan; Rizzi, Manuela; Salazar-Sanchez, Vanesa; Anstey, Natasha; Asiminas, Antonios; Basu, Shinjini; Booker, Sam A.; Harris, Anjanette; Heyes, Sam; Jackson, Adam; Crocker-Buque, Alex; McMahon, Aoife C.; Till, Sally M.; Wijetunge, Lasani S.; Wyllie, David J. A.; Abbott, Catherine M.; O'Leary, Timothy; Kind, Peter C.

BRAIN COMMUNICATIONS

IF4.5

2025-03-26

OAAI

Yasmin, Farhana; Marwick, Katie F. M.; Hunter, Daniel W.; Nawaz, Sarfaraz; Marshall, Grant F.; Booker, Sam A.; Hardingham, Giles E.; Kind, Peter C.; Wyllie, David J. A.

Key roles of C2/GAP domains in SYNGAP1-related pathophysiology

Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder

IF6.9

2024-09-01

OAAI

Katsanevaki, Danai; Till, Sally M.; Buller-Peralta, Ingrid; Nawaz, Mohammad Sarfaraz; Louros, Susana R.; Kapgal, Vijayakumar; Tiwari, Shashank; Walsh, Darren; Anstey, Natasha J.; Petrovic, Nina G.; Cormack, Alison; Salazar-Sanchez, Vanesa; Harris, Anjanette; Farnworth-Rowson, William; Sutherland, Andrew; Watson, Thomas C.; Dimitrov, Siyan; Jackson, Adam D.; Arkell, Daisy; Biswal, Suryanarayan; Dissanayake, Kosala N.; Mizen, Lindsay A. M.; Perentos, Nikolas; Jones, Matt W.; Cousin, Michael A.; Booker, Sam A.; Osterweil, Emily K.; Chattarji, Sumantra; Wyllie, David J. A.; Gonzalez-Sulser, Alfredo; Hardt, Oliver; Wood, Emma R.; Kind, Peter C.

Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons

IF5.5

2024-06-14

OAAI

Simoes de Oliveira, Laura; O'Leary, Heather E.; Nawaz, Sarfaraz; Loureiro, Rita; Davenport, Elizabeth C.; Baxter, Paul; Louros, Susana R.; Dando, Owen; Perkins, Emma; Peltier, Julien; Trost, Matthias; Osterweil, Emily K.; Hardingham, Giles E.; Cousin, Michael A.; Chattarji, Sumantra; Booker, Sam A.; Benke, Tim A.; Wyllie, David J. A.; Kind, Peter C.

Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3-/y rat model of autism

IF6.9

2023-04-01

OAAI

Sharma, Shreya Das; Reddy, Bharath Kumar; Pal, Rakhi; Ritakari, Tuula E.; Cooper, James D.; Selvaraj, Bhuvaneish T.; Kind, Peter C.; Chandran, Siddharthan; Wyllie, David J. A.; Chattarji, Sumantra

Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model

IF5.5

2022-07-18

OAAI

Anstey, Natasha J.; Kapgal, Vijayakumar; Tiwari, Shashank; Watson, Thomas C.; Toft, Anna K. H.; Dando, Owen R.; Inkpen, Felicity H.; Baxter, Paul S.; Kozic, Zrinko; Jackson, Adam D.; He, Xin; Nawaz, Mohammad Sarfaraz; Kayenaat, Aiman; Bhattacharya, Aditi; Wyllie, David J. A.; Chattarji, Sumantra; Wood, Emma R.; Hardt, Oliver; Kind, Peter C.

BRAIN COMMUNICATIONS

IF4.5

2021-10-26

OAAI

Barton, Samantha K.; Magnani, Dario; James, Owen G.; Livesey, Matthew R.; Selvaraj, Bhuvaneish T.; James, Owain T.; Perkins, Emma M.; Gregory, Jenna M.; Cleary, Elaine; Ausems, C. Rosanne M.; Carter, Roderick N.; Vasistha, Navneet A.; Zhao, Chen; Burr, Karen; Story, David; Cardinali, Alessandra; Morton, Nicholas M.; Hardingham, Giles E.; Wyllie, David J. A.; Chandran, Siddharthan

Correction of amygdalar dysfunction in a rat model of fragile X syndrome

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction C9ORF72重复扩增皮层神经元的网络特性改变是由于突触功能障碍

IF6.9

2021-10-01

OAAI

Fernandes, Giselle; Mishra, Pradeep K.; Nawaz, Mohammad Sarfaraz; Donlin-Asp, Paul G.; Rahman, Mohammed Mostafizur; Hazra, Anupam; Kedia, Sonal; Kayenaat, Aiman; Songara, Dheeraj; Wyllie, David J. A.; Schuman, Erin M.; Kind, Peter C.; Chattarji, Sumantra

MOLECULAR NEURODEGENERATION

IF17.5

2021-03-04

OAAI

Perkins, Emma M.; Burr, Karen; Banerjee, Poulomi; Mehta, Arpan R.; Dando, Owen; Selvaraj, Bhuvaneish T.; Suminaite, Daumante; Nanda, Jyoti; Henstridge, Christopher M.; Gillingwater, Thomas H.; Hardingham, Giles E.; Wyllie, David J. A.; Chandran, Siddharthan; Livesey, Matthew R.

Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome

Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns

IF6.9

2020-08-01

OAAI

Booker, Sam A.; de Oliveira, Laura Simoes; Anstey, Natasha J.; Kozic, Zrinko; Dando, Owen R.; Jackson, Adam D.; Baxter, Paul S.; Isom, Lori L.; Sherman, Diane L.; Hardingham, Giles E.; Brophy, Peter J.; Wyllie, David J. A.; Kind, Peter C.

Altered dendritic spine function and integration in a mouse model of fragile X syndrome 脆性X综合征小鼠模型中树突棘功能的改变和整合

IF5.5

2020-06-19

OAAI

Das Sharma, Shreya; Pal, Rakhi; Reddy, Bharath Kumar; Selvaraj, Bhuvaneish T.; Raj, Nisha; Samaga, Krishna Kumar; Srinivasan, Durga J.; Ornelas, Loren; Sareen, Dhruv; Livesey, Matthew R.; Bassell, Gary J.; Svendsen, Clive N.; Kind, Peter C.; Chandran, Siddharthan; Chattarji, Sumantra; Wyllie, David J. A.

Cellular and synaptic phenotypes lead to disrupted information processing in Fmr1-KO mouse layer 4 barrel cortex

IF15.7

2019-10-23

OAAI

Booker, Sam A.; Domanski, Aleksander P. F.; Dando, Owen R.; Jackson, Adam D.; Isaac, John T. R.; Hardingham, Giles E.; Wyllie, David J. A.; Kind, Peter C.

Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction

IF15.7

2019-10-23

OAAI

Domanski, Aleksander P. F.; Booker, Sam A.; Wyllie, David J. A.; Isaac, John T. R.; Kind, Peter C.

MOLECULAR PSYCHIATRY

IF10.1

2019-09-03

OAAI

Vasistha, Navneet A.; Johnstone, Mandy; Barton, Samantha K.; Mayerl, Steffen E.; Selvaraj, Bhuvaneish Thangaraj; Thomson, Pippa A.; Dando, Owen; Grunewald, Ellen; Alloza, Clara; Bastin, Mark E.; Livesey, Matthew R.; Economides, Kyriakos; Magnani, Dario; Makedonopolou, Paraskevi; Burr, Karen; Story, David J.; Blackwood, Douglas H. R.; Wyllie, David J. A.; McIntosh, Andrew M.; Millar, J. Kirsty; Ffrench-Constant, Charles; Hardingham, Giles E.; Lawrie, Stephen M.; Chandran, Siddharthan

Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2019-05-29

OAAI

Asiminas, Antonis; Jackson, Adam D.; Louros, Susana R.; Till, Sally M.; Spano, Teresa; Dando, Owen; Bear, Mark F.; Chattarji, Sumantra; Hardingham, Giles E.; Osterweil, Emily K.; Wyllie, David J. A.; Wood, Emma R.; Kind, Peter C.

BRAIN

IF11.7

2018-12-12

153

OAAI

Strehlow, Vincent; Heyne, Henrike O.; Vlaskamp, Danique R. M.; Marwick, Katie F. M.; Rudolf, Gabrielle; De Bellescize, Julitta; Biskup, Saskia; Brilstra, Eva H.; Brouwer, Oebele F.; Callenbach, Petra M. C.; Hentschel, Julia; Hirsch, Edouard; Kind, Peter C.; Mignot, Cyril; Platzer, Konrad; Rump, Patrick; Skehel, Paul A.; Wyllie, David J. A.; Hardingham, Giles E.; van Ravenswaaij-Arts, Conny M. A.; Lesca, Gaetan; Lemke, Johannes R.; Arzimanoglou, Alexis; Augustijn, Paul B.; Van Bogaert, Patrick; Bourry, Helene; Burfeind, Peter; Chu, Yoyo; Chung, Brian; Doummar, Diane; Edery, Patrick; Fattal-Valevski, Aviva; Fradin, Melanie; Gerard, Marion; de Geus, Christa; Gunning, Boudewijn; Hasaerts, Danielle; Helbig, Ingo; Helbig, Katherine L.; Jamra, Rami; Lyver, Melanie Jennesson; Wassink-Ruiter, Jolien S. Klein; Koolen, David A.; Lederer, Damien; Lunsing, Roelineke J.; Mathot, Mikael; Maurey, Helene; Menascu, Shay; Michel, Anne; Mirzaa, Ghayda; Mitter, Diana; Muhle, Hiltrud; Moller, Rikke S.; Nava, Caroline; O'Brien, Margaret; van Pinxteren-Nagler, Evelyn; van Riesen, Anne; Rougeot, Christelle; Sanlaville, Damien; Schieving, Jolanda H.; Syrbe, Steffen; Veenstra-Knol, Hermine E.; Verbeek, Nienke; Ville, Dorothee; Vos, Yvonne J.; Vrielynck, Pascal; Wagner, Sabrina; Weckhuysen, Sarah; Willemsen, Marjolein H.

Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging

MOLECULAR PSYCHIATRY

IF10.1

2018-11-06

OAAI

Johnstone, Mandy; Vasistha, Navneet A.; Barbu, Miruna C.; Dando, Owen; Burr, Karen; Christopher, Edward; Glen, Sophie; Robert, Christelle; Fetit, Rana; Macleod, Kenneth G.; Livesey, Matthew R.; St Clair, David; Blackwood, Douglas H. R.; Millar, Kirsty; Carragher, Neil O.; Hardingham, Giles E.; Wyllie, David J. A.; Johnstone, Eve C.; Whalley, Heather C.; McIntosh, Andrew M.; Lawrie, Stephen M.; Chandran, Siddharthan

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences NMDA受体组成的发育转变独立于GluN2亚基特异性GluN2 C端序列进行

Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism (vol 8, 15132, 2017)

IF6.9

2018-10-01

OAAI

McKay, Sean; Ryan, Tomas J.; McQueen, Jamie; Indersmitten, Tim; Marwick, Katie F. M.; Hasel, Philip; Kopanitsa, Maksym, V; Baxter, Paul S.; Martel, Marc-Andre; Kind, Peter C.; Wyllie, David J. A.; O'Dell, Thomas J.; Grant, Seth G. N.; Hardingham, Giles E.; Komiyama, Noboru H.

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity C9ORF72重复扩增导致运动神经元对Ca2可渗透的AMPA受体介导的兴奋性毒性的脆弱性

IF15.7

2018-02-06

OAAI

Hasel, Philip; Dando, Owen; Jiwaji, Zoeb; Baxter, Paul; Todd, Alison C.; Heron, Samuel; Markus, Nora M.; McQueen, Jamie; Hampton, David W.; Torvell, Megan; Tiwari, Sachin S.; Mckay, Sean; Eraso-Pichot, Abel; Zorzano, Antonio; Masgrau, Roser; Galea, Elena; Chandran, Siddharthan; Wyllie, David J. A.; Simpson, T. Ian; Hardingham, Giles E.