未登录 In Vivo PET Imaging of [18F]CHDI-385, a Radioligand for Mutant Huntingtin Aggregates in a Mouse Model of Huntington DiseaseDisease [18F]CHDI-385的体内PET成像,该放射性配体用于亨廷顿病小鼠模型中突变亨廷顿蛋白聚集物的检测 Zajicek, Franziska; Elvas, Filipe; Miranda, Alan; Akkermans, Jordy; Verhaeghe, Jeroen; Dominguez, Celia; Doot, Robert; Khetarpal, Vinod; Bard, Jonathan; Liu, Longbin; Staelens, Steven; Bertoglio, Daniele 分享 收藏
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Pharmacodynamic biomarkers responsive to mutant huntingtin lowering in a Huntington's disease mouse model 对降低亨廷顿病小鼠模型中突变亨廷顿蛋白反应的药效学生物标志物 Marchionini, Deanna M.; De Lombaerde, Stef; van Rijswijk, Joelle; Zajicek, Franziska; Everix, Liesbeth; Miranda, Alan; Aaltonen, Mari J.; Kluger, Carleen M.; Wild, Thomas; Kakoulidou, Aglaia; Gundelach, Jannis; Fieblinger, Tim; Fentz, Joachim; Rosinski, Jim; Obenauer, John; Greene, Jonathan R.; Liu, Longbin; Munoz-Sanjuan, Ignacio; Verhoye, Marleen; Verhaeghe, Jeroen; Bard, Jonathan; Staelens, Steven; Bertoglio, Daniele 分享 收藏
The Cerebrospinal Fluid Aβ1-42/Aβ1-40 Ratio Improves Concordance with Amyloid-PET for Diagnosing Alzheimer's Disease in a Clinical Setting 脑脊液Aβ1-42/Aβ1-40比率可改善与淀粉样蛋白-PET的一致性,以在临床环境中诊断阿尔茨海默氏病 Niemantsverdriet, Ellis; Ottoy, Julie; Somers, Charisse; De Roeck, Ellen; Struyfs, Hanne; Soetewey, Femke; Verhaeghe, Jeroen; Van den Bossche, Tobi; Van Mossevelde, Sara; Goeman, Johan; De Deyn, Peter Paul; Marien, Peter; Versijpt, Jan; Sleegers, Kristel; Van Broeckhoven, Christine; Wyffels, Leonie; Albert, Adrien; Ceyssens, Sarah; Stroobants, Sigrid; Staelens, Steven; Bjerke, Maria; Engelborghs, Sebastiaan 分享 收藏
Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates Akkermans, Jordy; Miranda, Alan; Verhaeghe, Jeroen; Elvas, Filipe; Zajicek, Franziska; Bard, Jonathan; Liu, Longbin; Khetarpal, Vinod; Doot, Robert; Staelens, Steven; Bertoglio, Daniele 分享 收藏
Preclinical evaluation of the novel [18F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease Zajicek, Franziska; Verhaeghe, Jeroen; De Lombaerde, Stef; Van Eetveldt, Annemie; Miranda, Alan; Munoz-Sanjuan, Ignacio; Dominguez, Celia; Khetarpal, Vinod; Bard, Jonathan; Liu, Longbin; Staelens, Steven; Bertoglio, Daniele 分享 收藏
Dynamic neuroreceptor positron emission tomography in non-anesthetized rats using point source based motion correction: A feasibility study with [11C]ABP688 Kroll, Tina; Miranda, Alan; Drechsel, Alexandra; Beer, Simone; Lang, Markus; Drzezga, Alexander; Rosa-Neto, Pedro; Verhaeghe, Jeroen; Elmenhorst, David; Bauer, Andreas 分享 收藏
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In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using 11C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease Bertoglio, Daniele; Weiss, Alison R.; Liguore, William; Martin, Lauren Drew; Hobbs, Theodore; Templon, John; Srinivasan, Sathya; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Khetarpal, Vinod; Verhaeghe, Jeroen; Staelens, Steven; Link, Jeanne; Liu, Longbin; Bard, Jonathan A.; McBride, Jodi L. 分享 收藏
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Validation, kinetic modeling, and test-retest reproducibility of [18F]SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2A in mice Bertoglio, Daniele; Zajicek, Franziska; De Lombaerde, Stef; Miranda, Alan; Stroobants, Sigrid; Wang, Yuchuan; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Bard, Jonathan; Liu, Longbin; Verhaeghe, Jeroen; Staelens, Steven 分享 收藏
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Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease Bertoglio, Daniele; Bard, Jonathan; Hessmann, Manuela; Liu, Longbin; Gaertner, Annette; De Lombaerde, Stef; Huscher, Britta; Zajicek, Franziska; Miranda, Alan; Peters, Finn; Herrmann, Frank; Schaertl, Sabine; Vasilkovska, Tamara; Brown, Christopher J.; Johnson, Peter D.; Prime, Michael E.; Mills, Matthew R.; Van der Linden, Annemie; Mrzljak, Ladislav; Khetarpal, Vinod; Wang, Yuchuan; Marchionini, Deanna M.; Skinbjerg, Mette; Verhaeghe, Jeroen; Dominguez, Celia; Staelens, Steven; Munoz-Sanjuan, Ignacio 分享 收藏
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Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease Bertoglio, Daniele; Verhaeghe, Jeroen; Miranda, Alan; Wyffels, Leonie; Stroobants, Sigrid; Mrzljak, Ladislav; Khetarpal, Vinod; Skinbjerg, Mette; Liu, Longbin; Dominguez, Celia; Munoz-Sanjuan, Ignacio; Bard, Jonathan; Staelens, Steven 分享 收藏