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Tim Luetkens

university of maryland school of medicine

29H指数
120论文数
2.1K被引数
收录论文 55
发表时间
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Targeting PI3K decreases trogocytosis-mediated CAR T cell fratricide靶向PI3K可降低吞噬胞吐介导的CAR T细胞自相残杀
errLeukemia
IF13.4
err2026-09-04
err0
errOAAI
errTarang Sharma; Maday Galeana Figueroa; Kishan Kumar Nyati; Ravi K. Shah; Meera Mohan; Parameswaran Hari; Tim Luetkens; Sabarinath Venniyil Radhakrishnan
err分享
err收藏
Preventing trogocytosis by cathepsin B inhibition augments CAR T-cell function通过抑制组织蛋白酶B防止吞噬作用增强了CAR T细胞功能
errSignal Transduction and Targeted Therapy
IF52.7
err2026-04-22
err0
errOAAI
errKenneth A. Dietze; Kiet Nguyen; Aashli Pathni; Frank Fazekas; Wenxiang Sun; Ethan Rosati; Jillian M. Baker; Maday Galeana Figueroa; Etse Gebru; Daniel Yamoah; Rediet Mulatu; Alexander Wang; Aaron P. Rapoport; David H. Lum; Xiaoxuan Fan; Sabarinath V. Radhakrishnan; Djordje Atanackovic; Arpita Upadhyaya; Tim Luetkens
err分享
err收藏
Engineering of a sweeping antibody against IL-16 for the treatment of autoimmune diseases and cancer
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBaker, Jillian; Wang, Alexander; Sun, Wenxiang; Luetkens, Tim
err分享
err收藏
Interleukin-16 preferentially binds naïve, activated T cells and promotes physiological T cell activation
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errBaker, Jillian; Gorga, Katrina; Singh, Nevil J.; Luetkens, Tim
err分享
err收藏
Cathepsin B causes trogocytosis-mediated CAR T cell dysfunction
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errDietze, Kenneth A.; Nguyen, Kiet; Pathni, Aashli; Fazekas, Frank; Gebru, Etse; Sun, Wenxiang; Rosati, Ethan; Lum, David; Rapoport, Aaron; Fan, Xiaoxuan; Atanackovic, Djordje; Upadhyaya, Arpita; Luetkens, Tim
err分享
err收藏
Novel cell therapy for the efficient intracellular delivery of genetically encoded payloads
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errWang, Alexander; Martos Esteban, Andrea; Karatt-Vellatt, Aneesh; Luetkens, Tim
err分享
err收藏
Coordinated antiviral immune response in a patient with myeloma and systemic adenovirus infection post-BCMA CAR T cells
errBLOOD ADVANCES
IF7.1
err2024-11-18
err0
errOAAI
errKocoglu, Mehmet H.; Luetkens, Tim; Bork, Jacqueline T.; Baddley, John; Omili, Destiny; Gebru, Etse; Mulatu, Rediet; Yamoah, Daniel; Iraguha, Thierry; Fan, Xiaoxuan; Lesho, Patricia; Yousaf, Mohammad; Baker, Jillian M.; Dietze, Kenneth A.; Hankey, Kim G.; Badros, Ashraf; Yared, Jean A.; Rapoport, Aaron P.; Hardy, Nancy M.; Atanackovic, Djordje
err分享
err收藏
A novel multicolor fluorescent spot assay for the functional assessment of chimeric antigen receptor (CAR) T-cell products
errCYTOTHERAPY
IF3.2
err2024-04-01
err2
PREAI
errAtanackovic, Djordje; Iraguha, Thierry; Omili, Destiny; Avila, Stephanie V.; Fan, Xiaoxuan; Kocoglu, Mehmet; Gebru, Etse; Baker, Jillian M.; Dishanthan, Nishanthini; Dietze, Kenneth A.; Oluwafemi, Ayooluwakiitan; Hardy, Nancy M.; Yared, Jean A.; Hankey, Kim; Dahiya, Saurabh; Rapoport, Aaron P.; Luetkens, Tim
err分享
err收藏
Engineering sweeping antibodies for the clearance of tumor-derived, protumorigenic cytokines
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errBaker, Jillian M.; Singh, Nevil J.; Luetkens, Tim
err分享
err收藏
Targeting trogocytosis through cathepsin B inhibition enhances CAR T cell persistence
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errDietze, Kenneth A.; Olson, Michael L.; Gebru, Etse; Atanackovic, Djordje; Rapoport, Aaron P.; Luetkens, Tim
err分享
err收藏
Immune-mediated facial nerve paralysis in a myeloma patient post B-cell maturation antigen-targeted chimeric T cells
errHAEMATOLOGICA
IF7.9
err2023-09-07
err4
errOAAI
errKathari, Yamini K.; Ahmad, Haroon; Kallen, Michael E.; Koka, Rima; Omili, Destiny; Iraguha, Thierry; Clement, Jean; Pham, Lily; Khalid, Mazhar; Fan, Xiaoxuan; Gebru, Etse; Lesho, Patricia; Park, Esther; Dishanthan, Nishanthini; Baker, Jillian M.; Dietze, Kenneth A.; Hankey, Kim G.; Badros, Ashraf; Yared, Jean A.; Dahiya, Saurabh; Hardy, Nancy M.; Kocoglu, Hakan; Luetkens, Tim; Rapoport, Aaron P.; Atanackovic, Djordje
err分享
err收藏
Bypassing the cytokine sink: IL-2-independent IL-2 receptor signaling
errMOLECULAR THERAPY
IF12
err2023-08-01
err0
errOAAI
errLuetkens, Tim
err分享
err收藏
Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-07-19
err12
PREAI
errVander Mause, Erica R.; Baker, Jillian M.; Dietze, Kenneth A.; Radhakrishnan, Sabarinath V.; Iraguha, Thierry; Omili, Destiny; Davis, Patricia; Chidester, Sadie L.; Modzelewska, Katarzyna; Panse, Jens; Marvin, James E.; Olson, Michael L.; Steinbach, Mary; Ng, David P.; Lim, Carol S.; Atanackovic, Djordje; Luetkens, Tim
err分享
err收藏
Chimeric antigen receptor (CAR) T cells for the treatment of a kidney transplant patient with post-transplant lymphoproliferative disorder (PTLD)
errHUMAN VACCINES & IMMUNOTHERAPEUTICS
IF3.5
err2023-06-06
err4
errOAAI
errKline, Kathryn; Chen, Wengen; Kallen, Michael E.; Koka, Rima; Omili, Destiny; Fan, Xiaoxuan; Iraguha, Thierry; Gebru, Etse; Dishanthan, Nishanthini; Baker, Jillian M.; Dietze, Kenneth A.; Yared, Jean A.; Hankey, Kim; Dahiya, Saurabh; Niederhaus, Silke V.; Dunleavy, Kieron; Hardy, Nancy M.; Luetkens, Tim; Rapoport, Aaron P.; Atanackovic, Djordje
err分享
err收藏
A Novel Multicolor Enzyme-linked Immunosorbent Spot Assay for the Functional Assessment of CAR T Cell Products
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errIraguha, Thierry; Omili, Destiny; Gebru, Etse; Hardy, Nancy M.; Luetkens, Tim; Rapoport, Aaron P.; Atanackovic, Djordje
err分享
err收藏
Roadmap to affinity-tuned antibodies for enhanced chimeric antigen receptor T cell function and selectivity增强嵌合抗原受体T细胞功能和选择性的亲和力调节抗体路线图
errTRENDS IN BIOTECHNOLOGY
IF14.9
err2022-07-01
err21
PREAI
errMause, Erica R. Vander; Atanackovic, Djordje; Lim, Carol S.; Luetkens, Tim
err分享
err收藏
Engineering anti-CD229 CAR T cell selectivity for multiple myeloma
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-05-01
err0
PREAI
errBaker, Jillian; Radhakrishnan, Sabarinath Venniyil; Olson, Michael; Atanackovic, Djordje; Luetkens, Tim; Vander Mause, Erica
err分享
err收藏
ITGA4 knockout prevents blood-brainbarrier migration of chimeric antigen receptor T cells
errJOURNAL OF IMMUNOLOGY
IF3.4
err2022-05-01
err0
PREAI
errDietze, Kenneth A.; Morales, Erin; Luetkens, Tim
err分享
err收藏
Low-affinity CAR T cells exhibit reduced trogocytosis, preventing rapid antigen loss, and increasing CAR T cell expansion
errLEUKEMIA
IF13.4
err2022-04-30
err58
errOAAI
errOlson, Michael L.; Mause, Erica R. Vander; Radhakrishnan, Sabarinath V.; Brody, Joshua D.; Rapoport, Aaron P.; Welm, Alana L.; Atanackovic, Djordje; Luetkens, Tim
err分享
err收藏
Impaired immune response to COVID-19 vaccination in patients with B-cell malignancies after CD19 CAR T-cell therapy
errBLOOD ADVANCES
IF7.1
err2022-01-24
err22
errOAAI
errDahiya, Saurabh; Luetkens, Tim; Lutfi, Forat; Avila, Stephanie; Iraguha, Thierry; Margiotta, Philip; Hankey, Kim G.; Lesho, Patricia; Law, Jennie Y.; Lee, Seung T.; Baddley, John; Kocoglu, Mehmet; Yared, Jean A.; Hardy, Nancy M.; Rapoport, Aaron P.; Atanackovic, Djordje
err分享
err收藏

研究方向

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