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Z

Zachary A. Bornholdt

Scripps Research Institute
H指数:34
被引数:3,580

个人简介

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教育背景

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工作经历

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荣誉奖项

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Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus

亲合力与可变域间距显著影响针对克里米亚-刚果出血热病毒的双特异性抗体的治疗效力

MBIO
IF4.7
2025-05-140
OA
Wang, Albert; Monticelli, Stephanie R.; Wirchnianski, Ariel S.; Abelson, Dafna M.; Kuehne, Ana I.; Bakken, Russell R.; Middlecamp, Marissa; Weingart, Michael; Vergnolle, Olivia; Bornholdt, Zachary A.; Moyer, Crystal L.; Berrigan, Jacob L.; West, Brandyn R.; Fels, J. Maximilian; Zeitlin, Larry; Herbert, Andrew S.; Chandran, Kartik; Bikash, Chowdhury Raihan
Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies
PLOS PATHOGENS
IF4.9
2024-04-113
OAAI
Wirchnianski, Ariel S.; Nyakatura, Elisabeth K.; Herbert, Andrew S.; Kuehne, Ana I.; Abbasi, Shawn A.; Florez, Catalina; Storm, Nadia; Mckay, Lindsay G. A.; Dailey, Leandrew; Kuang, Erin; Abelson, Dafna M.; Wec, Anna Z.; Chakraborti, Srinjoy; Holtsberg, Frederick W.; Shulenin, Sergey; Bornholdt, Zachary A.; Aman, M. Javad; Honko, Anna N.; Griffiths, Anthony; Dye, John M.; Chandran, Kartik; Lai, Jonathan R.
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease

与remdesivir和单克隆抗体联合治疗可保护非人灵长类动物免受晚期苏丹病毒病的侵害

JCI INSIGHT
IF6.1
2022-05-2325
OA
Cross, Robert W.; Bornholdt, Zachary A.; Prasad, Abhishek N.; Woolsey, Courtney; Borisevich, Viktoriya; Agans, Krystle N.; Deer, Daniel J.; Abelson, Dafna M.; Kim, Do H.; Shestowsky, William S.; Campbell, Lioudmila A.; Bunyan, Elaine; Geisbert, Joan B.; Dobias, Natalie S.; Fenton, Karla A.; Porter, Danielle P.; Zeitlin, Larry; Geisbert, Thomas W.
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-03-1619
OA
Mittler, Eva; Wec, Anna Z.; Tynell, Janne; Guardado-Calvo, Pablo; Wigren-Bystrom, Julia; Polanco, Laura C.; O'Brien, Cecilia M.; Slough, Megan M.; Abelson, Dafna M.; Serris, Alexandra; Sakharkar, Mrunal; Pehau-Arnaudet, Gerard; Bakken, Russell R.; Geoghegan, James C.; Jangra, Rohit K.; Keller, Markus; Zeitlin, Larry; Vapalahti, Olli; Ulrich, Rainer G.; Bornholdt, Zachary A.; Ahlm, Clas; Rey, Felix A.; Dye, John M.; Bradfute, Steven B.; Strandin, Tomas; Herbert, Andrew S.; Forsell, Mattias N. E.; Walker, Laura M.; Chandran, Kartik
Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
CELL REPORTS
IF6.9
2021-08-0125
OAAI
Doyle, Michael P.; Kose, Nurgun; Borisevich, Viktoriya; Binshtein, Elad; Amaya, Moushimi; Nagel, Marcus; Annand, Edward J.; Armstrong, Erica; Bombardi, Robin; Dong, Jinhui; Schey, Kevin L.; Broder, Christopher C.; Zeitlin, Larry; Kuang, Erin A.; Bornholdt, Zachary A.; West, Brandyn R.; Geisbert, Thomas W.; Cross, Robert W.; Crowe, James E., Jr.
Therapy for Argentine hemorrhagic fever in nonhuman primates with a humanized monoclonal antibody

用人源化单克隆抗体治疗非人灵长类动物的阿根廷出血性发热

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-03-0810
OAAI
Zeitlin, Larry; Cross, Robert W.; Geisbert, Joan B.; Borisevich, Viktoriya; Agans, Krystle N.; Prasad, Abhishek N.; Enterlein, Sven; Aman, M. Javad; Bornholdt, Zachary A.; Brennan, Miles B.; Campbell, Lioudmila; Kim, Do; Mlakar, Neil; Moyer, Crystal L.; Pauly, Michael H.; Shestowsky, William; Whaley, Kevin J.; Fenton, Karla A.; Geisbert, Thomas W.
Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine

人b细胞对黄色发热17D疫苗反应的纵向动力学

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-03-0966
OAAI
Wec, Anna Z.; Haslwanter, Denise; Abdiche, Yasmina N.; Shehata, Laila; Pedreno-Lopez, Nuria; Moyer, Crystal L.; Bornholdt, Zachary A.; Lilov, Asparouh; Nett, Juergen H.; Jangra, Rohit K.; Brown, Michael; Watkins, David I.; Ahlm, Clas; Forsell, Mattias N.; Rey, Felix A.; Barba-Spaeth, Giovanna; Chandran, Kartik; Walker, Laura M.
Development of an antibody cocktail for treatment of Sudan virus infection
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-02-0321
OAAI
Herbert, Andrew S.; Froude, Jeffery W.; Ortiz, Ramon A.; Kuehne, Ana I.; Dorosky, Danielle E.; Bakken, Russell R.; Zak, Samantha E.; Josleyn, Nicole M.; Musiychuk, Konstantin; Jones, R. Mark; Green, Brian; Streatfield, Stephen J.; Wec, Anna Z.; Bohorova, Natasha; Bohorov, Ognian; Kim, Do H.; Pauly, Michael H.; Velasco, Jesus; Whaley, Kevin J.; Stonier, Spencer W.; Bornholdt, Zachary A.; Chandran, Kartik; Zeitlin, Larry; Sampey, Darryl; Yusibov, Vidadi; Dye, John M.
Analytical Validation of the ReEBOV Antigen Rapid Test for Point-of-Care Diagnosis of Ebola Virus Infection
JOURNAL OF INFECTIOUS DISEASES
IF4.5
2016-08-3128
OAAI
Cross, Robert W.; Boisen, Matthew L.; Millett, Molly M.; Nelson, Diana S.; Oottamasathien, Darin; Hartnett, Jessica N.; Jones, Abigal B.; Goba, Augustine; Momoh, Mambu; Fullah, Mohamed; Bornholdt, Zachary A.; Fusco, Marnie L.; Abelson, Dafna M.; Oda, Shunichiro; Brown, Bethany L.; Ha Pham; Rowland, Megan M.; Agans, Krystle N.; Geisbert, Joan B.; Heinrich, Megan L.; Kulakosky, Peter C.; Shaffer, Jeffrey G.; Schieffelin, John S.; Kargbo, Brima; Gbetuwa, Momoh; Gevao, Sahr M.; Wilson, Russell B.; Saphire, Erica Ollmann; Pitts, Kelly R.; Khan, Sheik Humarr; Grant, Donald S.; Geisbert, Thomas W.; Branco, Luis M.; Garry, Robert F.

研究方向

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D
Dafna M. Abelson
H 指数:25论文数:51被引数:2,220
E
Erica Ollmann Saphire
H 指数:63论文数:357被引数:2.1万
L
Larry Zeitlin
H 指数:43论文数:138被引数:7,315
T
Thomas W. Geisbert
H 指数:93论文数:346被引数:2.9万
R
Robert W. Cross
H 指数:43论文数:159被引数:6,196
K
Kartik Chandran
H 指数:61论文数:258被引数:1.5万
J
Joan B. Geisbert
H 指数:60论文数:216被引数:1.2万
V
Viktoriya Borisevich
H 指数:36论文数:195被引数:4,888
K
Krystle N. Agans
H 指数:39论文数:114被引数:4,436
C
Crystal L. Moyer
H 指数:21论文数:42被引数:1,752