David C. Lamb - Publications, H-index & Citations

David C. Lamb

Swansea University

52H指数

169论文数

1.3W被引数

收录论文 78

发表时间

New Generation Modified Azole Antifungals against Multidrug-Resistant Candida auris 新一代改良唑类抗真菌剂对抗耐多药耳念珠菌

Journal of Medicinal Chemistry

IF6.8

2025-06-23

OAAI

Yiyuan Chen; Yunxiao Li; Kazi S. Nahar; Md. Mahbub Hasan; Caleb Marsh; Melanie Clifford; Godwin A. Aleku; Steven L. Kelly; David C. Lamb; Chengetai Diana Mpamhanga; Ilias Kounatidis; Ajit J. Shah; Charlotte K. Hind; J. Mark Sutton; Khondaker Miraz Rahman

Crystal structure of cytochrome P450 NysL and the structural basis for stereo- and regio-selective oxidation of antifungal macrolides

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2025-03-01

OAAI

Murarka, Vidhi C.; Kim, Jenny S.; Lamb, David C.; Kelly, Steven L.; Poulos, Thomas L.; Follmer, Alec H.

Vertebrate endocrine disruptors induce sex-reversal in blue mussels

SCIENTIFIC REPORTS

IF3.9

2024-10-12

OAAI

Evensen, K. Garrett; Rusin, Emily; Robinson, William E.; Price, Claire L.; Kelly, Steven L.; Lamb, David C.; Goldstone, Jared V.; Poynton, Helen C.

Identification of Potent and Selective Inhibitors of Acanthamoeba: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-04-29

OAAI

Hargrove, Tatiana Y.; Lamb, David C.; Wawrzak, Zdzislaw; Hull, Marcus; Kelly, Steven L.; Guengerich, F. Peter; Lepesheva, Galina I.

Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2023-08-01

OAAI

Goldstone, Jared, V; Lamb, David C.; Kelly, Steven L.; Lepesheva, Galina I.; Stegeman, John J.

Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics

SCIENTIFIC REPORTS

IF3.9

2022-09-28

OAAI

Hargrove, Tatiana Y.; Lamb, David C.; Smith, Jarrod A.; Wawrzak, Zdzislaw; Kelly, Steven L.; Lepesheva, Galina, I

Metabolic arsenal of giant viruses: Host hijack or self-use?巨型病毒的代谢武器库: 宿主劫持还是自我使用？

ELIFE

IF0

2022-07-08

OAAI

Belhaouari, Djamal Brahim; De Souza, Gabriel Augusto Pires; Lamb, David C.; Kelly, Steven L.; Goldstone, Jared, V; Stegeman, John J.; Colson, Philippe; La Scola, Bernard; Aherfi, Sarah

Structural analysis of P450 AmphL from Streptomyces nodosus provides insights into substrate selectivity of polyene macrolide antibiotic biosynthetic P450s

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-04-01

OAAI

Amaya, Jose A.; Lamb, David C.; Kelly, Steven L.; Caffrey, Patrick; Murarka, Vidhi C.; Poulos, Thomas L.

Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish

SCIENTIFIC REPORTS

IF3.9

2021-12-13

OAAI

Brun, Nadja R.; Salanga, Matthew C.; Mora-Zamorano, Francisco X.; Lamb, David C.; Goldstone, Jared, V; Stegeman, John J.

Incomplete tricarboxylic acid cycle and proton gradient in Pandoravirus massiliensis: is it still a virus?

ISME JOURNAL

IF10

2021-09-23

OAAI

Aherfi, Sarah; Belhaouari, Djamal Brahim; Pinault, Lucile; Baudoin, Jean-Pierre; Decloquement, Philippe; Abrahao, Jonatas; Colson, Philippe; Levasseur, Anthony; Lamb, David C.; Chabriere, Eric; Raoult, Didier; La Scola, Bernard

Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2020-10-08

OAAI

Lamb, David C.; Hargrove, Tatiana Y.; Zhao, Bin; Wawrzak, Zdzislaw; Goldstone, Jared, V; Nes, William David; Kelly, Steven L.; Waterman, Michael R.; Stegeman, John J.; Lepesheva, Galina, I

On the occurrence of cytochrome P450 in viruses 关于病毒中细胞色素P450的发生

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-06-05

OAAI

Lamb, David C.; Follmer, Alec H.; Goldstone, Jared V.; Nelson, David R.; Warrilow, Andrew G.; Price, Claire L.; True, Marie Y.; Kelly, Steven L.; Poulos, Thomas L.; Stegeman, John J.

Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders 斑马鱼中的细胞色素P450 20A1: 克隆，调控和多动症的潜在参与

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2016-04-01

OAAI

Lemaire, Benjamin; Kubota, Akira; O'Meara, Conor M.; Lamb, David C.; Tanguay, Robert L.; Goldstone, Jared V.; Stegeman, John J.

Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution 性激素生物合成中细胞色素P450羟化酶的遗传和结构分析: 顺序起源和随后的进化

MOLECULAR PHYLOGENETICS AND EVOLUTION

IF3.6

2016-01-01

OAAI

Goldstone, Jared V.; Sundaramoorthy, Munirathinam; Zhao, Bin; Waterman, Michael R.; Stegeman, John J.; Lamb, David C.

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-09-01

135

OAAI

Hargrove, Tatiana Y.; Wawrzak, Zdzislaw; Lamb, David C.; Guengerich, F. Peter; Lepesheva, Galina I.

Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51)

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2015-08-01

OAAI

Lamb, David C.; Warrilow, Andrew G. S.; Rolley, Nicola J.; Parker, Josie E.; Nes, W. David; Smith, Stephen N.; Kelly, Diane E.; Kelly, Steven L.

Functional and structural characterisation of a viral cytochrome b5

FEBS LETTERS

IF3

2013-10-04

PREAI

Reid, Emma L.; Weynberg, Karen D.; Love, John; Isupov, Michail N.; Littlechild, Jennifer A.; Wilson, William H.; Kelly, Steven L.; Lamb, David C.; Allen, Michael J.

Streptomyces cytochromes P450: applications in drug metabolism 链霉菌细胞色素P450: 在药物代谢中的应用

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2013-06-06

PREAI

Lamb, David C.; Waterman, Michael R.; Zhao, Bin

Unusual properties of the cytochrome P450 superfamily 细胞色素P450超家族的异常性质

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2013-02-19

OAAI

Lamb, David C.; Waterman, Michael R.