Holger Flechsig

Kanazawa University

H指数:14

被引数:755

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Coiled-Coil Domain Kinking Controls Laminin-332 Cleavage by Elastase

卷曲螺旋结构域的弯曲控制弹性蛋白酶对层粘连蛋白-332的切割

Journal of Molecular Biology

IF4.5

2026-08-140

OAAI

Structural Dynamics of the Afamin/Wnt3a Complex Mediated by the Afamin Hydrophobic Pocket

Afamin疏水口袋介导的Afamin/Wnt3a复合物的结构动力学

Nano Letters

IF9.1

2026-04-010

PRE

High-Speed Atomic Force Microscopy Reveals Disordered Region-Mediated Structural Plasticity of Anaplastic Lymphoma Kinase Fusion Proteins Induced by Inhibitors

ACS Nano

IF16

2026-01-200

OAAI

Structural dynamics of mixed-subunit CaMKIIα/β heterododecamers filmed by high-speed AFM

混合亚基CaMKIIα/β异十二聚体的结构动力学，通过高速AFM成像技术进行观察

Nature Communications

IF15.7

2025-12-240

OAAI

Ligand Binding to the Membrane-Distal Domain of the Met Receptor Induces Dimerization at the Membrane-Proximal Domain

配体与Met受体的膜远端结构域结合，诱导膜近端结构域发生二聚化。

ACS Nano

IF16

2025-11-260

PRE

MET Enhances Amivantamab Binding to EGFR and Antibody-Dependent Cellular Toxicity

MET增强Amivantamab与EGFR的结合及抗体依赖性细胞毒性

Cancer Science

IF4.3

2025-11-090

OAAI

Flexible Fitting to Infer Atomistic-Precision Models of Large-Amplitude Conformational Dynamics in Biomolecules from High-Speed Atomic Force Microscopy Imaging

ACS NANO

IF16

2025-09-011

PRE

High-Speed Atomic Force Microscopy Reveals Fluctuations and Dimer Splitting of the N-Terminal Domain of GluA2 Ionotropic Glutamate Receptor-Auxiliary Subunit Complex

ACS NANO

IF16

2024-08-240

PRE

Structural heterogeneity of the ion and lipid channel TMEM16F

离子和脂质通道TMEM16F的结构异质性

NATURE COMMUNICATIONS

IF15.7

2024-01-024

OAAI

Structural Dynamics of E6AP E3 Ligase HECT Domain and Involvement of a Flexible Hinge Loop in the Ubiquitin Chain Synthesis Mechanism

NANO LETTERS

IF9.1

2023-12-061

OAAI

Predicting the placement of biomolecular structures on AFM substrates based on electrostatic interactions

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-11-282

OAAI

Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy

通过高速原子力显微镜对工作中的单个CaMKII全酶进行成像

SCIENCE ADVANCES

IF12.5

2023-06-307

OAAI

Protein dynamics by the combination of high-speed AFM and computational modeling

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-06-0117

OAAI

Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy

通过高速原子力显微镜揭示的金黄色葡萄球菌Cas9的靶DNA结合和切割的动力学

ACS NANO

IF16

2023-02-273

PRE

BioAFMviewer software for simulation atomic force microscopy of molecular structures and conformational dynamics

JOURNAL OF STRUCTURAL BIOLOGY-X

IF5.1

2023-01-018

OAAI

Novel DNA Aptamer for CYP24A1 Inhibition with Enhanced Antiproliferative Activity in Cancer Cells

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2022-04-1815

PRE

An ultra-wide scanner for large-area high-speed atomic force microscopy with megapixel resolution

SCIENTIFIC REPORTS

IF3.9

2021-06-2130

OAAI

Simple mechanics of protein machines

JOURNAL OF THE ROYAL SOCIETY INTERFACE

IF3.5

2019-06-1926

OAAI

Deciphering Intrinsic Inter-subunit Couplings that Lead to Sequential Hydrolysis of F1-ATPase Ring

BIOPHYSICAL JOURNAL

IF3.1

2017-10-018

OAAI

Design of Elastic Networks with Evolutionary Optimized Long-Range Communication as Mechanical Models of Allosteric Proteins

BIOPHYSICAL JOURNAL

IF3.1

2017-08-0140

OAAI

Holger Flechsig

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