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H

Hiroyuki Yamakoshi

Tohoku University

24H指数
116论文数
2.7K被引数
收录论文 37
发表时间
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Identification of a novel small-molecule compound that suppresses depolarization-induced CYP11B2 expression and aldosterone production in KCNJ5 mutant adrenocortical cells鉴定一种新型小分子化合物，该化合物可抑制KCNJ5突变肾上腺皮质细胞中除极化诱导的CYP11B2表达和醛固酮产生
errBiochemical and Biophysical Research Communications
IF2.2
err2026-09-12
err0
errOAAI
errYuri Otsubo; Hiroki Shimada; Keita Hoshi; Ryo Ito; Thanh Phuong Nguyen; Hiroyuki Yamakoshi; Kosuke Ohsawa; Hirofumi Ueda; Hidetoshi Tokuyama; Yoshiro Saito; Yoshiharu Iwabuchi; Takayuki Doi; Yasuhiro Nakamura; Akira Sugawara; Atsushi Yokoyama
err分享
err收藏
Nrf2 activation by the monocarbonyl curcumin derivative GO-Y015 confers cellular protection against arsenite toxicity by reducing intracellular arsenic levels单羰基姜黄素衍生物GO-Y015通过降低细胞内砷水平激活Nrf2，赋予细胞对抗亚砷酸盐毒性的保护作用
errScientific Reports
IF3.9
err2026-04-18
err0
errOAAI
errMd. Tanvir Islam; Hiroki Taguchi; Hiroyuki Yamakoshi; Wang Yinuo; Hiroyuki Shibata; Yoshiharu Iwabuchi; Takashi Toyama; Yoshiro Saito
err分享
err收藏
Alkyne Two-Phase Strategy: Rapid Generation of TK-285-Derived PROTACs as BRD4 Degraders炔烃两相策略：TK-285衍生的PROTACs作为BRD4降解剂的快速生成
errJournal of Medicinal Chemistry
IF6.8
err2026-03-19
err0
errOAAI
errHiroyuki Yamakoshi; Ryo Watanabe; Ryosuke Segawa; Ryosuke Ishihara; Ryo Tachibana; Genki Kudo; Shota Nagasawa; Satoshi Yamanaka; Ayano Ito; Hiroyuki Takeda; Tatsuya Sawasaki; Ryunosuke Yoshino; Takatsugu Hirokawa; Takayuki Doi; Noriyasu Hirasawa; Yoshiharu Iwabuchi
err分享
err收藏
Oxidative Generation of Isobenzofurans for Intermolecular Cycloadditions异苯并呋喃的氧化生成及其分子间环加成反应
errThe Journal of Organic Chemistry
IF3.6
err2025-11-18
err0
PREAI
errEmi Nakatsugawa; Keigetsu Higashiyama; Hiroyuki Yamakoshi; Eisaku Ohashi; Seiichi Nakamura
err分享
err收藏
Visualizing Thiol Stress Responses in Cells with a Water-Soluble Raman Sensor利用水溶性拉曼传感器可视化细胞中的硫醇应激反应
errANALYTICAL CHEMISTRY
IF6.7
err2025-11-01
err0
PREAI
errYamakoshi, Hiroyuki; Wang, Meichen; Koga, Keisuke; Kajimoto, Shinji; Kuriyama, Yuse; Sasano, Yusuke; Akaike, Takaaki; Iwabuchi, Yoshiharu; Nakabayashi, Takakazu
err分享
err收藏
In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID基于AirID的异双功能分子在细胞内邻近靶向验证方法（适用于CRBN或VHL结合剂）
errCommunications Biology
IF5.1
err2025-08-30
err0
errOAAI
errKohdai Yamada; Satoshi Yamanaka; Hiroyuki Yamakoshi; Aki Kohyama; Yoshiharu Iwabuchi; Hidetaka Kosako; Tatsuya Sawasaki
err分享
err收藏
Alkyne-tag Raman imaging and sensing of bioactive compounds炔烃标记拉曼成像与生物活性化合物传感
errNATURE REVIEWS METHODS PRIMERS
IF56
err2025-03-27
err0
PREAI
errDodo, Kosuke; Tipping, William J.; Yamakoshi, Hiroyuki; Egoshi, Syusuke; Kubo, Toshiki; Kumamoto, Yasuaki; Faulds, Karen; Graham, Duncan; Sodeoka, Mikiko
err分享
err收藏
Development of a fluorous trapping reagent for rapid detection of electrophilic reactive metabolites (vol 16, pg 3810, 2024)一种用于快速检测亲电活性代谢物的全氟化捕获试剂的开发（卷16，页3810，2024）
errANALYTICAL METHODS
IF2.6
err2025-01-01
err0
errOAAI
errAkagi, Yusuke; Yamakoshi, Hiroyuki; Iwabuchi, Yoshiharu
err分享
err收藏
Oxidative generation of isobenzofurans from phthalans: application to the formal synthesis of (±)-morphine
errCHEMICAL SCIENCE
IF7.4
err2024-01-01
err0
errOAAI
errKage, Mirai; Yamakoshi, Hiroyuki; Tabata, Manami; Ohashi, Eisaku; Noguchi, Kimihiro; Watanabe, Takeshi; Uchida, Manato; Takada, Minetatsu; Ikeuchi, Kazutada; Nakamura, Seiichi
err分享
err收藏
LiHMDS-Mediated Deprotonative Coupling of Toluenes with KetonesLiHMDS介导的甲苯与酮的去质子偶联
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2023-02-13
err4
PREAI
errShigeno, Masanori; Kajima, Akihisa; Toyama, Eito; Korenaga, Toshinobu; Yamakoshi, Hiroyuki; Nozawa-Kumada, Kanako; Kondo, Yoshinori
err分享
err收藏
Ratiometric analysis of reversible thia-Michael reactions using nitrile-tagged molecules by Raman microscopy
errCHEMICAL COMMUNICATIONS
IF4.2
err2023-01-01
err4
PREAI
errYamakoshi, Hiroyuki; Shibata, Daiki; Bando, Kazuki; Kajimoto, Shinji; Kohyama, Aki; Egoshi, Syusuke; Dodo, Kosuke; Iwabuchi, Yoshiharu; Sodeoka, Mikiko; Fujita, Katsumasa; Nakabayashi, Takakazu
err分享
err收藏
Multiple deuteration of triphenylphosphine and live-cell Raman imaging of deuterium-incorporated Mito-Q
errCHEMICAL COMMUNICATIONS
IF4.2
err2023-01-01
err7
PREAI
errMoriyama, Shogo; Mae, Miyu; Shibata, Daiki; Yamakoshi, Hiroyuki; Kajimoto, Shinji; Nakabayashi, Takakazu; Ishimoto, Takayoshi; Mogi, Kaiki; Sajiki, Hironao; Akai, Shuji; Sawama, Yoshinari
err分享
err收藏
Direct C-H Carboxylation Forming Polyfunctionalized Aromatic Carboxylic Acids by Combined Bronsted Bases
errORGANIC LETTERS
IF5
err2022-01-20
err15
PREAI
errShigeno, Masanori; Hanasaka, Kazuya; Tohara, Itsuki; Izumi, Koki; Yamakoshi, Hiroyuki; Kwon, Eunsang; Nozawa-Kumada, Kanako; Kondo, Yoshinori
err分享
err收藏
Quantitative Drug Dynamics Visualized by Alkyne-Tagged Plasmonic-Enhanced Raman Microscopy
errACS NANO
IF16
err2020-10-20
err50
PREAI
errKoike, Kota; Bando, Kazuki; Ando, Jun; Yamakoshi, Hiroyuki; Terayama, Naoki; Dodo, Kosuke; Smith, Nicholas Isaac; Sodeoka, Mikiko; Fujita, Katsumasa
err分享
err收藏
Total Syntheses of Marrubiin and Related Labdane Diterpene Lactones
errMOLECULES
IF4.6
err2020-04-01
err6
errOAAI
errSakagami, Yukari; Kondo, Naoki; Sawayama, Yuki; Yamakoshi, Hiroyuki; Nakamura, Seiichi
err分享
err收藏
A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model
errNATURE COMMUNICATIONS
IF15.7
err2018-07-10
err23
errOAAI
errTsuburaya, Naomi; Homma, Kengo; Higuchi, Tsunehiko; Balia, Andrii; Yamakoshi, Hiroyuki; Shibata, Norio; Nakamura, Seiichi; Nakagawa, Hidehiko; Ikeda, Shin-ichi; Umezawa, Naoki; Kato, Nobuki; Yokoshima, Satoshi; Shibuya, Masatoshi; Shimonishi, Manabu; Kojima, Hirotatsu; Okabe, Takayoshi; Nagano, Tetsuo; Naguro, Isao; Imamura, Keiko; Inoue, Haruhisa; Fujisawa, Takao; Ichijo, Hidenori
err分享
err收藏
Noncanonical Function of a Small-Molecular Virulence Factor Coronatine against Plant Immunity: An In Vivo Raman Imaging Approach
errACS CENTRAL SCIENCE
IF10.4
err2017-05-04
err18
errOAAI
errUeda, Minoru; Egoshi, Syusuke; Dodo, Kosuke; Ishimaru, Yasuhiro; Yamakoshi, Hiroyuki; Nakano, Takeshi; Takaoka, Yousuke; Tsukiji, Shinya; Sodeoka, Mikiko
err分享
err收藏
Alkyne-Tag SERS Screening and Identification of Small-Molecule-Binding Sites in Protein
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2016-10-14
err81
PREAI
errAndo, Jun; Asanuma, Miwako; Dodo, Kosuke; Yamakoshi, Hiroyuki; Kawata, Satoshi; Fujita, Katsumasa; Sodeoka, Mikiko
err分享
err收藏
Total Syntheses of (+)-Marrubiin and (-)-Marrulibacetal
errORGANIC LETTERS
IF5
err2016-06-24
err16
errOAAI
errYamakoshi, Hiroyuki; Sawayama, Yuki; Akahori, Yoshihiro; Kato, Marie; Nakamura, Seiichi
err分享
err收藏
Construction of Bridged Polycyclic Systems by Polyene Cyclization
errCHEMISTRY-A EUROPEAN JOURNAL
IF3.7
err2015-10-22
err16
errOAAI
errSuzuki, Keisuke; Yamakoshi, Hiroyuki; Nakamura, Seiichi
err分享
err收藏

研究方向

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