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Identification of isoAsp7-Aβ as a major Aβ variant in Alzheimer's disease, dementia with Lewy bodies and vascular dementia 鉴定isoasp7-a β 是阿尔茨海默氏病,路易体痴呆和血管性痴呆的主要a β 变体 Schrempel, Sarah; Kottwitz, Anna Katharina; Piechotta, Anke; Gnoth, Kathrin; Bueschgens, Luca; Hartlage-Ruebsamen, Maike; Morawski, Markus; Schenk, Mathias; Kleinschmidt, Martin; Serrano, Geidy E.; Beach, Thomas G.; Rostagno, Agueda; Ghiso, Jorge; Heneka, Michael T.; Walter, Jochen; Wirths, Oliver; Schilling, Stephan; Rossner, Steffen 分享 收藏
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Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells Boudesco, Christophe; Nonneman, Annelies; Cinti, Alessandro; Picardi, Paola; Redaelli, Loredana; Swijsen, Sofie; Roewe, Julian; Reinhardt, Peter; Ibach, Melanie; Walter, Jochen; Pocock, Jennifer M.; Ren, Yi; Driguez, Pierre-Alexandre; Dargazanli, Gihad; Eyquem, Stephanie; Proto, Jonathan; Flores-Morales, Amilcar; Pradier, Laurent 分享 收藏
FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer's disease expressing APOE4 Crivelli, Simone M.; Luo, Qian; van Kruining, Daan; Giovagnoni, Caterina; Mane-Damas, Marina; den Hoedt, Sandra; Berkes, Dusan; De Vries, Helga E.; Mulder, Monique T.; Walter, Jochen; Waelkens, Etienne; Derua, Rita; Swinnen, Johannes V.; Dehairs, Jonas; Wijnands, Erwin P. M.; Bieberich, Erhard; Losen, Mario; Martinez -Martinez, Pilar 分享 收藏
Seeding, maturation and propagation of amyloid β-peptide aggregates in Alzheimer's disease 阿尔茨海默氏病中淀粉样 β-肽聚集体的播种,成熟和繁殖 Li, TXiaohang; Ospitalieri, Simona; Robberechts, Tessa; Hofmann, Linda; Schmid, Christina; Upadhaya, Ajeet Rijal; Koper, Marta J.; von Arnim, Christine A. F.; Kumar, Sathish; Willem, Michael; Gnoth, Kathrin; Ramakers, Meine; Schymkowitz, Joost; Rousseau, Frederic; Walter, Jochen; Ronisz, Alicja; Balakrishnan, Karthikeyan; Thal, Dietmar Rudolf 分享 收藏
Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice den Hoedt, Sandra; Crivelli, Simone M.; Leijten, Frank P. J.; Losen, Mario; Stevens, Jo A. A.; Mane-Damas, Marina; de Vries, Helga E.; Walter, Jochen; Mirzaian, Mina; Sijbrands, Eric J. G.; Aerts, Johannes M. F. G.; Verhoeven, Adrie J. M.; Martinez-Martinez, Pilar; Mulder, Monique T. 分享 收藏
TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits Joshi, Pranav; Riffel, Florian; Kumar, Sathish; Villacampa, Nadia; Theil, Sandra; Parhizkar, Samira; Haass, Christian; Colonna, Marco; Heneka, Michael T.; Arzberger, Thomas; Herms, Jochen; Walter, Jochen 分享 收藏
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CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease Crivelli, Simone M.; Luo, Qian; Stevens, Jo A. A.; Giovagnoni, Caterina; van Kruining, Daan; Bode, Gerard; den Hoedt, Sandra; Hobo, Barbara; Scheithauer, Anna-Lena; Walter, Jochen; Mulder, Monique T.; Exley, Christopher; Mold, Matthew; Mielke, Michelle M.; De Vries, Helga E.; Wouters, Kristiaan; van den Hove, Daniel L. A.; Berkes, Dusan; Ledesma, Maria Dolores; Verhaagen, Joost; Losen, Mario; Bieberich, Erhard; Martinez-Martinez, Pilar 分享 收藏
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Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation Vilalta, Anna; Zhou, Ye; Sevalle, Jean; Griffin, Jennifer K.; Satoh, Kanayo; Allendorf, David H.; De, Suman; Puigdellivol, Mar; Bruzas, Arturas; Burguillos, Miguel A.; Dodd, Roger B.; Chen, Fusheng; Zhang, Yalun; Flagmeier, Patrick; Needham, Lisa-Maria; Enomoto, Masahiro; Qamar, Seema; Henderson, James; Walter, Jochen; Fraser, Paul E.; Klenerman, David; Lee, Steven F.; St George-Hyslop, Peter; Brown, Guy C. 分享 收藏
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Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe Crivelli, Simone M.; van Kruining, Daan; Luo, Qian; Stevens, Jo A. A.; Giovagnoni, Caterina; Paulus, Andreas; Bauwens, Matthias; Berkes, Dusan; de Vries, Helga E.; Mulder, Monique T.; Walter, Jochen; Waelkens, Etienne; Derua, Rita; Swinnen, Johannes, V; Dehairs, Jonas; Mottaghy, Felix M.; Losen, Mario; Bieberich, Erhard; Martinez-Martinez, Pilar 分享 收藏