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K

Keiichi Motoyama

kumamoto university
H指数:36
被引数:4,391

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荣誉奖项

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A water-soluble β-cyclodextrin polymer reduces cholesterol accumulation and autophagy dysfunction in vitro and in Niemann-Pick type C disease model mice

一种水溶性β-环糊精聚合物可减少体外胆固醇积累和自噬功能障碍，以及在尼曼-皮克C型疾病模型小鼠中的表现

Carbohydrate Polymers
IF12.5
2025-11-140
OAAI
Yuto Kubohira; Nanami Okano; Toru Taharabaru; Arina Ishimatsu; Takumi Era; Kazunori Yanagihara; Kandai Ishikura; Yoshinori Nakagawa; Taishi Higashi; Keiichi Motoyama
Inability of α-cyclodextrins to accommodate cholesterol potentially underlies their lack of efficacy and ototoxicity in Niemann-Pick disease type C treatment

α-环糊精无法容纳胆固醇，这可能是其治疗尼曼-匹克C型病缺乏疗效和具有耳毒性的潜在原因。

Scientific Reports
IF3.9
2025-08-220
OAAI
Yusei Yamada; Mayuko Tanaka; Yusei Ikeda; Yuki Kondo; Toru Takeo; Naomi Nakagata; Toru Miwa; Hiroki Takeda; Yorihisa Orita; Keiichi Motoyama; Taishi Higashi; Hidetoshi Arima; Takahiro Seki; Yuki Kurauchi; Hiroshi Katsuki; Katsumi Higaki; Kotaro Matsusaka; Kentaro Minami; Naoki Yoshikawa; Ryuji Ikeda; Muneaki Matsuo; Tetsumi Irie; Yoichi Ishitsuka
Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment
CLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
2023-08-246
OAAI
Yamada, Yusei; Fukaura-Nishizawa, Madoka; Nishiyama, Asami; Ishii, Akira; Kawata, Tatsuya; Shirakawa, Aina; Tanaka, Mayuko; Kondo, Yuki; Takeo, Toru; Nakagata, Naomi; Miwa, Toru; Takeda, Hiroki; Orita, Yorihisa; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Seki, Takahiro; Kurauchi, Yuki; Katsuki, Hiroshi; Higaki, Katsumi; Minami, Kentaro; Yoshikawa, Naoki; Ikeda, Ryuji; Matsuo, Muneaki; Irie, Tetsumi; Ishitsuka, Yoichi
Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss
BIOMEDICINE & PHARMACOTHERAPY
IF7.5
2022-11-015
OAAI
Yamada, Yusei; Miwa, Toru; Nakashima, Masaki; Shirakawa, Aina; Ishii, Akira; Namba, Nanami; Kondo, Yuki; Takeo, Toru; Nakagata, Naomi; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Kurauchi, Yuki; Seki, Takahiro; Katsuki, Hiroshi; Okada, Yasuyo; Ichikawa, Atsushi; Higaki, Katsumi; Hayashi, Ken; Minami, Kentaro; Yoshikawa, Naoki; Ikeda, Ryuji; Ishikawa, Yoshihide; Kajii, Tomohito; Tachii, Kyoko; Takeda, Hiroki; Orita, Yorihisa; Matsuo, Muneaki; Irie, Tetsumi; Ishitsuka, Yoichi
Multifunctional Therapeutic Cyclodextrin-Appended Dendrimer Complex for Treatment of Systemic and Localized Amyloidosis

多功能治疗性环糊精-附加树状聚合物复合物，用于治疗系统性和局部性淀粉样变性

ACS APPLIED MATERIALS & INTERFACES
IF8.2
2022-09-022
PRE
Inoue, Masamichi; Higashi, Taishi; Hayashi, Yuya; Onodera, Risako; Fujisawa, Kazuya; Taharabaru, Toru; Yokoyama, Ryoma; Ouchi, Kenta; Misumi, Yohei; Ueda, Mitsuharu; Inoue, Yasuteru; Mizuguchi, Mineyuki; Saito, Takashi; Saido, Takaomi C.; Ando, Yukio; Arima, Hidetoshi; Motoyama, Keiichi; Jono, Hirofumi

研究方向

暂未获取到该数据
H
Hidetoshi Arima
H 指数:49论文数:333被引数:8,758
T
Taishi Higashi
H 指数:34论文数:217被引数:3,607
R
Risako Onodera
H 指数:22论文数:106被引数:1,301
F
Fumitoshi Hirayama
H 指数:48论文数:324被引数:1.0万
K
Kaneto Uekama
H 指数:55论文数:533被引数:1.6万
T
Toru Taharabaru
H 指数:8论文数:38被引数:176
T
Tetsumi Irie
H 指数:44论文数:383被引数:1.0万
T
Takayuki Anno
H 指数:11论文数:40被引数:287
Y
Yukio Ando
H 指数:119论文数:5,114被引数:8.1万
H
Hirofumi Jono
H 指数:44论文数:241被引数:5,836