未登录 Antagonizing Il10 and Il4 signaling via intracerebral decoy receptor expression attenuates Aβ accumulation Koller, Emily J.; Mcfarland, Karen N.; Angelle, Conner; Howard, John; Ryu, Danny; Dillon, Kristy D.; Erquizi, Aya; Beheray, Mihir; de la Cruz, Elsa Gonzalez; Cruz, Pedro E.; Lewis, Jada; Golde, Todd E.; Levites, Yona; Chakrabarty, Paramita 分享 收藏
Integrative proteomics identifies a conserved Aβ amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease Levites, Yona; Dammer, Eric B.; Ran, Yong; Tsering, Wangchen; Duong, Duc; Abreha, Measho; Gadhavi, Joshna; Lolo, Kiara; Trejo-Lopez, Jorge; Phillips, Jennifer; Iturbe, Andrea; Erquizi, Aya; Moore, Brenda D.; Ryu, Danny; Natu, Aditya; Dillon, Kristy; Torrellas, Jose; Moran, Corey; Ladd, Thomas; Afroz, Farhana; Islam, Tariful; Jagirdar, Jaishree; Funk, Cory C.; Robinson, Max; Rangaraju, Srikant; Borchelt, David R.; Ertekin-Taner, Nilufer; Kelly, Jeffrey W.; Heppner, Frank L.; Johnson, Erik C. B.; McFarland, Karen; Levey, Allan I.; Prokop, Stefan; Seyfried, Nicholas T.; Golde, Todd E. 分享 收藏
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid Wojtas, Aleksandra M.; Dammer, Eric B.; Guo, Qi; Ping, Lingyan; Shantaraman, Ananth; Duong, Duc M.; Yin, Luming; Fox, Edward J.; Seifar, Fatemeh; Lee, Edward B.; Johnson, Erik C. B.; Lah, James J.; Levey, Allan I.; Levites, Yona; Rangaraju, Srikant; Golde, Todd E.; Seyfried, Nicholas T. 分享 收藏
AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model AAV介导的anti-BACE1 VHH递送减轻阿尔茨海默病模型的病理 Marino, Marika; Zhou, Lujia; Rincon, Melvin Y.; Callaerts-Vegh, Zsuzsanna; Verhaert, Jens; Wahis, Jerome; Creemers, Eline; Yshii, Lidia; Wierda, Keimpe; Saito, Takashi; Marneffe, Catherine; Voytyuk, Iryna; Wouters, Yessica; Dewilde, Maarten; Duque, Sandra, I; Vincke, Cecile; Levites, Yona; Golde, Todd E.; Saido, Takaomi C.; Muyldermans, Serge; Liston, Adrian; De Strooper, Bart; Holt, Matthew G. 分享 收藏
Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy Levites, Yona; Funk, Cory; Wang, Xue; Chakrabarty, Paramita; McFarland, Karen N.; Bramblett, Baxter; O'Neal, Veronica; Liu, Xufei; Ladd, Thomas; Robinson, Max; Allen, Mariet; Carrasquillo, Minerva M.; Dickson, Dennis; Cruz, Pedro; Ryu, Danny; Li, Hong-Dong; Price, Nathan D.; Ertekin-Taner, NIlufer; Golde, Todd E. 分享 收藏
Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia 可溶性 α-突触核蛋白-抗体复合物激活hiPSC衍生的小胶质细胞中的NLRP3炎性体 Trudler, Dorit; Nazor, Kristopher L.; Eisele, Yvonne S.; Grabauskas, Titas; Dolatabadi, Nima; Parker, James; Sultan, Abdullah; Zhong, Zhenyu; Goodwin, Marshall S.; Levites, Yona; Golde, Todd E.; Kelly, Jeffery W.; Sierks, Michael R.; Schork, Nicholas J.; Karin, Michael; Ambasudhan, Rajesh; Lipton, Stuart A. 分享 收藏
Il-10 signaling reduces survival in mouse models of synucleinopathy Cockey, Samuel G.; McFarland, Karen N.; Koller, Emily J.; Brooks, Mieu M. T.; De La Cruz, Elsa Gonzalez; Cruz, Pedro E.; Ceballos-Diaz, Carolina; Rosario, Awilda M.; Levites, Yona R.; Borchelt, David R.; Golde, Todd E.; Giasson, Benoit, I; Chakrabarty, Paramita 分享 收藏
Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes Goodwin, Marshall S.; Sinyavskaya, Olga; Burg, Franklin; O'Neal, Veronica; Ceballos-Diaz, Carolina; Cruz, Pedro E.; Lewis, Jada; Giasson, Benoit, I; Davies, Peter; Golde, Todd E.; Levites, Yona 分享 收藏
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Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease Li, Hong-Dong; Funk, Cory C.; McFarland, Karen; Dammer, Eric B.; Allen, Mariet; Carrasquillo, Minerva M.; Levites, Yona; Chakrabarty, Paramita; Burgess, Jeremy D.; Wang, Xue; Dickson, Dennis; Seyfried, Nicholas T.; Duong, Duc M.; Lah, James J.; Younkin, Steven G.; Levey, Allan, I; Omenn, Gilbert S.; Ertekin-Taner, Nilufer; Golde, Todd E.; Price, Nathan D. 分享 收藏
Ass40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Ass42 toxicity inDrosophila De Mena, Lorena; Smith, Michael A.; Martin, Jason; Dunton, Katie L.; Ceballos-Diaz, Carolina; Jansen-West, Karen R.; Cruz, Pedro E.; Dillon, Kristy D.; Rincon-Limas, Diego E.; Golde, Todd E.; Moore, Brenda D.; Levites, Yona 分享 收藏
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Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models 阿尔茨海默病小鼠模型人脑转录组和功能解剖的Meta分析 Wan, Ying-Wooi; Al-Ouran, Rami; Mangleburg, Carl G.; Perumal, Thanneer M.; Lee, Tom, V; Allison, Katherine; Swarup, Vivek; Funk, Cory C.; Gaiteri, Chris; Allen, Mariet; Wang, Minghui; Neuner, Sarah M.; Kaczorowski, Catherine C.; Philip, Vivek M.; Howell, Gareth R.; Martini-Stoica, Heidi; Zheng, Hui; Mei, Hongkang; Zhong, Xiaoyan; Kim, Jungwoo Wren; Dawson, Valina L.; Dawson, Ted M.; Pao, Ping-Chieh; Tsai, Li-Huei; Haure-Mirande, Jean-Vianney; Ehrlich, Michelle E.; Chakrabarty, Paramita; Levites, Yona; Wang, Xue; Dammer, Eric B.; Srivastava, Gyan; Mukherjee, Sumit; Sieberts, Solveig K.; Omberg, Larsson; Dang, Kristen D.; Eddy, James A.; Snyder, Phil; Chae, Yooree; Amberkar, Sandeep; Wei, Wenbin; Hide, Winston; Preuss, Christoph; Ergun, Ayla; Ebert, Phillip J.; Airey, David C.; Mostafavi, Sara; Yu, Lei; Klein, Hans-Ulrich; Carter, Gregory W.; Collier, David A.; Golde, Todd E.; Levey, Allan, I; Bennett, David A.; Estrada, Karol; Townsend, T. Matthew; Zhang, Bin; Schadt, Eric; De Jager, Philip L.; Price, Nathan D.; Ertekin-Taner, Nilufer; Liu, Zhandong; Shulman, Joshua M.; Mangravite, Lara M.; Logsdon, Benjamin A. 分享 收藏
Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis Xu, Guilian; Fromholt, Susan E.; Chakrabarty, Paramita; Zhu, Fanchao; Liu, Xuefei; Pace, Michael C.; Koh, Jin; Golde, Todd E.; Levites, Yona; Lewis, Jada; Borchelt, David R. 分享 收藏
Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS Goodwin, Marshall S.; Croft, Cara L.; Futch, Hunter S.; Ryu, Daniel; Ceballos-Diaz, Carolina; Liu, Xuefei; Paterno, Giavanna; Mejia, Catalina; Deng, Doris; Menezes, Kimberly; Londono, Laura; Arjona, Kefren; Parianos, Mary; Truong, Van; Rostonics, Eva; Hernandez, Amanda; Boye, Sanford L.; Boye, Shannon E.; Levites, Yona; Cruz, Pedro E.; Golde, Todd E. 分享 收藏
Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus Forner, Stefania; Martini, Alessandra C.; Prieto, G. Aleph; Dang, Cindy T.; Rodriguez-Ortiz, Carlos J.; Reyes-Ruiz, Jorge Mauricio; Trujillo-Estrada, Laura; da Cunha, Celia; Andrews, Elizabeth J.; Phan, Jimmy; Ha, Jordan Vu; Chang, Allissa V. Z. D.; Levites, Yona; Cruz, Pedro E.; Ager, Rahasson; Medeiros, Rodrigo; Kitazawa, Masashi; Glabe, Charles G.; Cotman, Carl W.; Golde, Todd; Baglietto-Vargas, David; LaFerla, Frank M. 分享 收藏
An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes Futch, Hunter S.; McFarland, Karen N.; Moore, Brenda D.; Kuhn, M. Zino; Giasson, Benoit I.; Ladd, Thomas B.; Scott, Karen A.; Shapiro, Melanie R.; Nosacka, Rachel L.; Goodwin, Marshall S.; Ran, Yong; Cruz, Pedro E.; Ryu, Daniel H.; Croft, Cara L.; Levites, Yona; Janus, Christopher; Chakrabarty, Paramita; Judge, Andrew R.; Brusko, Todd M.; de Kloet, Annette D.; Krause, Eric G.; Golde, Todd E. 分享 收藏
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rAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies Croft, Cara L.; Cruz, Pedro E.; Ryu, Daniel H.; Ceballos-Diaz, Carolina; Strang, Kevin H.; Woody, Brittany M.; Lin, Wen-Lang; Deture, Michael; Rodriguez-Lebron, Edgardo; Dickson, Dennis W.; Chakrabarty, Paramita; Levites, Yona; Giasson, Benoit I.; Golde, Todd E. 分享 收藏
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